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B0QZV3

- B0QZV3_MOUSE

UniProt

B0QZV3 - B0QZV3_MOUSE

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Protein
Sodium/hydrogen exchanger
Gene
Slc9a6
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. sodium:proton antiporter activity Source: InterPro

GO - Biological processi

  1. axon extension Source: MGI
  2. brain-derived neurotrophic factor receptor signaling pathway Source: MGI
  3. dendrite extension Source: MGI
  4. dendritic spine development Source: MGI
  5. neuron projection morphogenesis Source: MGI
  6. proton transport Source: MGI
  7. regulation of neurotrophin TRK receptor signaling pathway Source: MGI
  8. regulation of pH Source: InterPro
  9. synapse organization Source: MGI
Complete GO annotation...

Keywords - Biological processi

AntiportUniRule annotationSAAS annotations, Ion transport, Sodium transportUniRule annotation, Transport

Keywords - Ligandi

Sodium

Names & Taxonomyi

Protein namesi
Recommended name:
Sodium/hydrogen exchangerUniRule annotation
Gene namesi
Name:Slc9a6Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome X

Organism-specific databases

MGIiMGI:2443511. Slc9a6.

Subcellular locationi

GO - Cellular componenti

  1. axon terminus Source: MGI
  2. axonal spine Source: MGI
  3. cytoplasmic vesicle Source: MGI
  4. dendrite Source: MGI
  5. early endosome Source: MGI
  6. endosome Source: MGI
  7. integral component of membrane Source: UniProtKB-KW
  8. late endosome Source: MGI
  9. mitochondrion Source: MGI
  10. plasma membrane Source: MGI
  11. recycling endosome Source: MGI
  12. synapse Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliB0QZV3.
SMRiB0QZV3. Positions 219-247, 338-365.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

TransmembraneUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00560000076802.
HOGENOMiHOG000172307.
HOVERGENiHBG055575.

Family and domain databases

InterProiIPR006153. Cation/H_exchanger.
IPR018422. Cation/H_exchanger_CPA1.
IPR002090. Na/H_exchanger_6.
IPR004709. NaH_exchanger.
[Graphical view]
PANTHERiPTHR10110. PTHR10110. 1 hit.
PfamiPF00999. Na_H_Exchanger. 1 hit.
[Graphical view]
PRINTSiPR01084. NAHEXCHNGR.
PR01088. NAHEXCHNGR6.
TIGRFAMsiTIGR00840. b_cpa1. 1 hit.

Sequencei

Sequence statusi: Complete.

B0QZV3-1 [UniParc]FASTAAdd to Basket

« Hide

MAGARRGWRL APVRRGVCGP RARPLMRPLW LLFAVSFFGW TGALDGSGGT    50
TRAMDEEIVS EKQAEESHRQ DSANLLIFIL LLTLTILTIW LFKHRRARFL 100
HETGLAMIYG LLVGLVLRYG IHVPSDVNNV TLSCEVQSSP TTLLVTFDPE 150
VFFNILLPPI IFYAGYSLKR RHFFRNLGSI LAYAFLGTAI SCFVIGSIMY 200
GCVTLMKVTG QLAGDFYFTD CLLFGAIVSA TDPVTVLAIF HELQVDVELY 250
ALLFGESVLN DAVAIVLSSS IVAYQPAGDN SHTFDVTAMF KSIGIFLGIF 300
SGSFAMGAAT GVVTALVTKF TKLREFQLLE TGLFFLMSWS TFLLAEAWGF 350
TGVVAVLFCG ITQAHYTYNN LSTESQHRTK QLFELLNFLA ENFIFSYMGL 400
TLFTFQNHVF NPTFVVGAFI AIFLGRAANI YPLSLLLNLG RRSKIGSNFQ 450
HMMMFAGLRG AMAFALAIRD TATYARQMMF STTLLIVFFT VWVFGGGTTA 500
MLSCLHIRVG VDSDQEHLGV PDNERRTTKA ESAWLFRMWY NFDHNYLKPL 550
LTHSGPPLTT TLPACCGPIA RCLTSPQAYE NQEQLKDDDS DLILNDGDIS 600
LTYGDSTVNT ESATASAPRR FMGNSSEDAL DRELTFGDHE LVIRGTRLVL 650
PMDDSEPALN SLDDTRHSPA 670
Length:670
Mass (Da):74,228
Last modified:April 8, 2008 - v1
Checksum:iF58983DFE9792463
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC048362 Genomic DNA. No translation available.
AL672085 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000114784; ENSMUSP00000110432; ENSMUSG00000060681.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC048362 Genomic DNA. No translation available.
AL672085 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali B0QZV3.
SMRi B0QZV3. Positions 219-247, 338-365.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000114784 ; ENSMUSP00000110432 ; ENSMUSG00000060681 .

Organism-specific databases

MGIi MGI:2443511. Slc9a6.

Phylogenomic databases

GeneTreei ENSGT00560000076802.
HOGENOMi HOG000172307.
HOVERGENi HBG055575.

Miscellaneous databases

NextBioi 35545469.
SOURCEi Search...

Family and domain databases

InterProi IPR006153. Cation/H_exchanger.
IPR018422. Cation/H_exchanger_CPA1.
IPR002090. Na/H_exchanger_6.
IPR004709. NaH_exchanger.
[Graphical view ]
PANTHERi PTHR10110. PTHR10110. 1 hit.
Pfami PF00999. Na_H_Exchanger. 1 hit.
[Graphical view ]
PRINTSi PR01084. NAHEXCHNGR.
PR01088. NAHEXCHNGR6.
TIGRFAMsi TIGR00840. b_cpa1. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The phagosomal proteome in interferon-gamma-activated macrophages."
    Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
    Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB0QZV3_MOUSE
AccessioniPrimary (citable) accession number: B0QZV3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: July 9, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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