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B0QZV3 (B0QZV3_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length670 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. [View classification] RuleBase RU003722

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000110432

Ontologies

Keywords
   Biological processAntiport SAAS SAAS006153 RuleBase RU003722
Ion transport
Sodium transport RuleBase RU003722
Transport
   Cellular componentMembrane
   DomainTransmembrane RuleBase RU003721
   LigandSodium
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processaxon extension

Inferred from sequence orthology PubMed 24035762. Source: MGI

brain-derived neurotrophic factor receptor signaling pathway

Inferred from mutant phenotype PubMed 24035762. Source: MGI

dendrite extension

Inferred from sequence orthology PubMed 24035762. Source: MGI

dendritic spine development

Inferred from mutant phenotype PubMed 24035762. Source: MGI

neuron projection morphogenesis

Inferred from sequence orthology PubMed 24035762. Source: MGI

proton transport

Inferred from mutant phenotype PubMed 24035762. Source: MGI

regulation of neurotrophin TRK receptor signaling pathway

Inferred from mutant phenotype PubMed 24035762. Source: MGI

regulation of pH

Inferred from electronic annotation. Source: InterPro

synapse organization

Inferred from mutant phenotype PubMed 24035762. Source: MGI

   Cellular_componentaxon terminus

Inferred from direct assay PubMed 23303939. Source: MGI

axonal spine

Inferred from direct assay PubMed 23303939. Source: MGI

cytoplasmic vesicle

Inferred from direct assay PubMed 23303939. Source: MGI

dendrite

Inferred from direct assay PubMed 23303939. Source: MGI

early endosome

Inferred from direct assay PubMed 24035762. Source: MGI

endosome

Inferred from direct assay PubMed 24035762. Source: MGI

integral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

late endosome

Inferred from direct assay PubMed 24035762. Source: MGI

mitochondrion

Inferred from direct assay PubMed 14651853. Source: MGI

plasma membrane

Inferred from direct assay PubMed 23303939. Source: MGI

recycling endosome

Inferred from direct assay PubMed 23303939PubMed 24035762. Source: MGI

synapse

Inferred from direct assay PubMed 24035762. Source: MGI

   Molecular_functionsodium:proton antiporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
B0QZV3 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: F58983DFE9792463

FASTA67074,228
        10         20         30         40         50         60 
MAGARRGWRL APVRRGVCGP RARPLMRPLW LLFAVSFFGW TGALDGSGGT TRAMDEEIVS 

        70         80         90        100        110        120 
EKQAEESHRQ DSANLLIFIL LLTLTILTIW LFKHRRARFL HETGLAMIYG LLVGLVLRYG 

       130        140        150        160        170        180 
IHVPSDVNNV TLSCEVQSSP TTLLVTFDPE VFFNILLPPI IFYAGYSLKR RHFFRNLGSI 

       190        200        210        220        230        240 
LAYAFLGTAI SCFVIGSIMY GCVTLMKVTG QLAGDFYFTD CLLFGAIVSA TDPVTVLAIF 

       250        260        270        280        290        300 
HELQVDVELY ALLFGESVLN DAVAIVLSSS IVAYQPAGDN SHTFDVTAMF KSIGIFLGIF 

       310        320        330        340        350        360 
SGSFAMGAAT GVVTALVTKF TKLREFQLLE TGLFFLMSWS TFLLAEAWGF TGVVAVLFCG 

       370        380        390        400        410        420 
ITQAHYTYNN LSTESQHRTK QLFELLNFLA ENFIFSYMGL TLFTFQNHVF NPTFVVGAFI 

       430        440        450        460        470        480 
AIFLGRAANI YPLSLLLNLG RRSKIGSNFQ HMMMFAGLRG AMAFALAIRD TATYARQMMF 

       490        500        510        520        530        540 
STTLLIVFFT VWVFGGGTTA MLSCLHIRVG VDSDQEHLGV PDNERRTTKA ESAWLFRMWY 

       550        560        570        580        590        600 
NFDHNYLKPL LTHSGPPLTT TLPACCGPIA RCLTSPQAYE NQEQLKDDDS DLILNDGDIS 

       610        620        630        640        650        660 
LTYGDSTVNT ESATASAPRR FMGNSSEDAL DRELTFGDHE LVIRGTRLVL PMDDSEPALN 

       670 
SLDDTRHSPA 

« Hide

References

« Hide 'large scale' references
[1]"The phagosomal proteome in interferon-gamma-activated macrophages."
Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[2]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J Ensembl ENSMUSP00000110432.
[3]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
Strain: C57BL/6J Ensembl ENSMUSP00000110432.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC048362 Genomic DNA. No translation available.
AL672085 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalB0QZV3.
SMRB0QZV3. Positions 219-247, 338-365.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000114784; ENSMUSP00000110432; ENSMUSG00000060681.

Organism-specific databases

MGIMGI:2443511. Slc9a6.

Phylogenomic databases

GeneTreeENSGT00560000076802.
HOGENOMHOG000172307.
HOVERGENHBG055575.

Family and domain databases

InterProIPR006153. Cation/H_exchanger.
IPR018422. Cation/H_exchanger_CPA1.
IPR002090. Na/H_exchanger_6.
IPR004709. NaH_exchanger.
[Graphical view]
PANTHERPTHR10110. PTHR10110. 1 hit.
PfamPF00999. Na_H_Exchanger. 1 hit.
[Graphical view]
PRINTSPR01084. NAHEXCHNGR.
PR01088. NAHEXCHNGR6.
TIGRFAMsTIGR00840. b_cpa1. 1 hit.
ProtoNetSearch...

Other

NextBio35545469.
SOURCESearch...

Entry information

Entry nameB0QZV3_MOUSE
AccessionPrimary (citable) accession number: B0QZV3
Entry history
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: July 9, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)