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Protein
Submitted name:

SUMO-conjugating enzyme UBC9

Gene

UBE2I

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei93Glycyl thioester intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Biological processUbl conjugation pathwayUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiB0QYN7.

Names & Taxonomyi

Protein namesi
Submitted name:
SUMO-conjugating enzyme UBC9Imported
Gene namesi
Name:UBE2IImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000103275.18.
HGNCiHGNC:12485. UBE2I.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000103275.

PTM / Processingi

Proteomic databases

MaxQBiB0QYN7.
PaxDbiB0QYN7.
PRIDEiB0QYN7.

Expressioni

Gene expression databases

BgeeiENSG00000103275.
ExpressionAtlasiB0QYN7. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliB0QYN7.
SMRiB0QYN7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 137UBIQUITIN_CONJUGAT_2InterPro annotationAdd BLAST131

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0424. Eukaryota.
COG5078. LUCA.
GeneTreeiENSGT00550000075088.
HOGENOMiHOG000233454.
HOVERGENiHBG063308.
OrthoDBiEOG091G0NAK.
PhylomeDBiB0QYN7.

Family and domain databases

CDDicd00195. UBCc. 1 hit.
Gene3Di3.10.110.10. 1 hit.
InterProiView protein in InterPro
IPR027230. Ubc9.
IPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
PANTHERiPTHR43927. PTHR43927. 1 hit.
PfamiView protein in Pfam
PF00179. UQ_con. 1 hit.
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiView protein in PROSITE
PS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B0QYN7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGIALSRLA QERKAWRKDH PFGFVAVPTK NPDGTMNLMN WECAIPGKKG
60 70 80 90 100
TPWEGGLFKL RMLFKDDYPS SPPKCKFEPP LFHPNVYPSG TVCLSILEED
110 120 130 140 150
KDWRPAITIK QILLGIQELL NEPNIQDPAQ AEAYTIYWLV AALAPLVAAP
160 170 180
PRPSQGRLAG REWRTQAHPT DSQGPRLCGE GRGA
Length:184
Mass (Da):20,458
Last modified:April 8, 2008 - v1
Checksum:iAD786FF443DC3A26
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC120498 Genomic DNA. No translation available.
AL031714 Genomic DNA. No translation available.
RefSeqiXP_005255597.1. XM_005255540.2.
XP_005255598.1. XM_005255541.4.
XP_011520946.1. XM_011522644.2.
XP_011520947.1. XM_011522645.1.
UniGeneiHs.302903.

Genome annotation databases

EnsembliENST00000402301; ENSP00000384361; ENSG00000103275.
GeneIDi7329.
UCSCiuc002clh.2. human.

Similar proteinsi

Entry informationi

Entry nameiB0QYN7_HUMAN
AccessioniPrimary (citable) accession number: B0QYN7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: October 25, 2017
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported