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Protein
Submitted name:

SUMO-conjugating enzyme UBC9

Gene

UBE2I

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionTransferaseSAAS annotation
Biological processUbl conjugation pathwayUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiB0QYN7

Names & Taxonomyi

Protein namesi
Submitted name:
SUMO-conjugating enzyme UBC9Imported
Gene namesi
Name:UBE2IImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000103275.18
HGNCiHGNC:12485 UBE2I

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000103275

PTM / Processingi

Proteomic databases

MaxQBiB0QYN7
PeptideAtlasiB0QYN7
PRIDEiB0QYN7

Expressioni

Gene expression databases

BgeeiENSG00000103275
ExpressionAtlasiB0QYN7 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliB0QYN7
SMRiB0QYN7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 137UBIQUITIN_CONJUGAT_2InterPro annotationAdd BLAST131

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0424 Eukaryota
COG5078 LUCA
GeneTreeiENSGT00550000075088
HOGENOMiHOG000233454
HOVERGENiHBG063308
OrthoDBiEOG091G0NAK
PhylomeDBiB0QYN7

Family and domain databases

CDDicd00195 UBCc, 1 hit
Gene3Di3.10.110.10, 1 hit
InterProiView protein in InterPro
IPR027230 Ubc9
IPR000608 UBQ-conjugat_E2
IPR023313 UBQ-conjugating_AS
IPR016135 UBQ-conjugating_enzyme/RWD
PANTHERiPTHR43927 PTHR43927, 1 hit
PfamiView protein in Pfam
PF00179 UQ_con, 1 hit
SUPFAMiSSF54495 SSF54495, 1 hit
PROSITEiView protein in PROSITE
PS00183 UBIQUITIN_CONJUGAT_1, 1 hit
PS50127 UBIQUITIN_CONJUGAT_2, 1 hit

Sequencei

Sequence statusi: Complete.

B0QYN7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGIALSRLA QERKAWRKDH PFGFVAVPTK NPDGTMNLMN WECAIPGKKG
60 70 80 90 100
TPWEGGLFKL RMLFKDDYPS SPPKCKFEPP LFHPNVYPSG TVCLSILEED
110 120 130 140 150
KDWRPAITIK QILLGIQELL NEPNIQDPAQ AEAYTIYWLV AALAPLVAAP
160 170 180
PRPSQGRLAG REWRTQAHPT DSQGPRLCGE GRGA
Length:184
Mass (Da):20,458
Last modified:April 8, 2008 - v1
Checksum:iAD786FF443DC3A26
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC120498 Genomic DNA No translation available.
AL031714 Genomic DNA No translation available.
RefSeqiXP_005255597.1, XM_005255540.2
XP_005255598.1, XM_005255541.4
XP_011520946.1, XM_011522644.2
XP_011520947.1, XM_011522645.1
UniGeneiHs.302903

Genome annotation databases

EnsembliENST00000402301; ENSP00000384361; ENSG00000103275
GeneIDi7329
UCSCiuc002clh.2 human

Similar proteinsi

Entry informationi

Entry nameiB0QYN7_HUMAN
AccessioniPrimary (citable) accession number: B0QYN7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: June 20, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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