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B0QYL8

- B0QYL8_HUMAN

UniProt

B0QYL8 - B0QYL8_HUMAN

Protein
Submitted name:

DNA-directed RNA polymerases I, II, and III subunit RPABC2

Gene

POLR2F

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. DNA-directed RNA polymerase activity Source: InterPro

    GO - Biological processi

    1. transcription, DNA-templated Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    DNA-directed RNA polymerases I, II, and III subunit RPABC2Imported
    Gene namesi
    Name:POLR2FImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 22

    Organism-specific databases

    HGNCiHGNC:9193. POLR2F.

    Expressioni

    Gene expression databases

    ArrayExpressiB0QYL8.

    Structurei

    3D structure databases

    ProteinModelPortaliB0QYL8.
    SMRiB0QYL8. Positions 1-98.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000225272.
    OMAiVEEFHEL.

    Family and domain databases

    Gene3Di3.90.940.10. 1 hit.
    InterProiIPR020708. DNA-dir_RNA_polK_14-18kDa_CS.
    IPR006110. Pol_omega/K/RPB6.
    IPR012293. RNAP_RPB6_omega.
    IPR006111. RpoK/Rpb6.
    [Graphical view]
    PANTHERiPTHR10773. PTHR10773. 1 hit.
    PfamiPF01192. RNA_pol_Rpb6. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000778. RpoK/RPB6. 1 hit.
    SUPFAMiSSF63562. SSF63562. 1 hit.
    PROSITEiPS01111. RNA_POL_K_14KD. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B0QYL8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSDNEDNFDG DDFDDVEEDE GLDDLENAEE EGQENVEILP SGERPQANQK    50
    RITTPYMTKY ERARVLGTRA LQIAMCAPVM VELEGETDPL LIAMKELKLL 100
    WGLEYTVLRP SYALAHSLGS FSISSR 126
    Length:126
    Mass (Da):14,185
    Last modified:April 8, 2008 - v1
    Checksum:iE01C76FBC7D44CF7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL031587 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000405557; ENSP00000384112; ENSG00000100142.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL031587 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali B0QYL8.
    SMRi B0QYL8. Positions 1-98.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000405557 ; ENSP00000384112 ; ENSG00000100142 .

    Organism-specific databases

    HGNCi HGNC:9193. POLR2F.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000225272.
    OMAi VEEFHEL.

    Miscellaneous databases

    ChiTaRSi POLR2F. human.
    NextBioi 35465776.

    Gene expression databases

    ArrayExpressi B0QYL8.

    Family and domain databases

    Gene3Di 3.90.940.10. 1 hit.
    InterProi IPR020708. DNA-dir_RNA_polK_14-18kDa_CS.
    IPR006110. Pol_omega/K/RPB6.
    IPR012293. RNAP_RPB6_omega.
    IPR006111. RpoK/Rpb6.
    [Graphical view ]
    PANTHERi PTHR10773. PTHR10773. 1 hit.
    Pfami PF01192. RNA_pol_Rpb6. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000778. RpoK/RPB6. 1 hit.
    SUPFAMi SSF63562. SSF63562. 1 hit.
    PROSITEi PS01111. RNA_POL_K_14KD. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence of human chromosome 22."
      Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., Clamp M., Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., Bagguley C., Bailey J., Barlow K.F., Bates K.N., Beasley O.P., Bird C.P., Blakey S.E., Bridgeman A.M.
      , Buck D., Burgess J., Burrill W.D., Burton J., Carder C., Carter N.P., Chen Y., Clark G., Clegg S.M., Cobley V.E., Cole C.G., Collier R.E., Connor R., Conroy D., Corby N.R., Coville G.J., Cox A.V., Davis J., Dawson E., Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M., Ellington A.G., Evans K.L., Fey J.M., Fleming K., French L., Garner A.A., Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C., Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., Hunt S.E., Jones M.C., Kershaw J., Kimberley A.M., King A., Laird G.K., Langford C.F., Leversha M.A., Lloyd C., Lloyd D.M., Martyn I.D., Mashreghi-Mohammadi M., Matthews L.H., Mccann O.T., Mcclay J., Mclaren S., McMurray A.A., Milne S.A., Mortimore B.J., Odell C.N., Pavitt R., Pearce A.V., Pearson D., Phillimore B.J.C.T., Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y., Rogers L., Ross M.T., Scott C.E., Sehra H.K., Skuce C.D., Smalley S., Smith M.L., Soderlund C., Spragon L., Steward C.A., Sulston J.E., Swann R.M., Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L., Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L., Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N., Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., Shintani A., Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., Roe B.A., Chen F., Chu L., Crabtree J., Deschamps S., Do A., Do T., Dorman A., Fang F., Fu Y., Hu P., Hua A., Kenton S., Lai H., Lao H.I., Lewis J., Lewis S., Lin S.-P., Loh P., Malaj E., Nguyen T., Pan H., Phan S., Qi S., Qian Y., Ray L., Ren Q., Shaull S., Sloan D., Song L., Wang Q., Wang Y., Wang Z., White J., Willingham D., Wu H., Yao Z., Zhan M., Zhang G., Chissoe S., Murray J., Miller N., Minx P., Fulton R., Johnson D., Bemis G., Bentley D., Bradshaw H., Bourne S., Cordes M., Du Z., Fulton L., Goela D., Graves T., Hawkins J., Hinds K., Kemp K., Latreille P., Layman D., Ozersky P., Rohlfing T., Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K., Nelson J., Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R., Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., Budarf M.L., McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., Edelmann L., Kim U.J., Shizuya H., Simon M.I., Dumanski J.P., Peyrard M., Kedra D., Seroussi E., Fransson I., Tapia I., Bruder C.E., O'Brien K.P., Wilkinson P., Bodenteich A., Hartman K., Hu X., Khan A.S., Lane L., Tilahun Y., Wright H.
      Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiB0QYL8_HUMAN
    AccessioniPrimary (citable) accession number: B0QYL8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 8, 2008
    Last sequence update: April 8, 2008
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3