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Protein
Submitted name:

Suppressor of cytokine signaling 8

Gene

SOCS8

Organism
Gasterosteus aculeatus (Three-spined stickleback)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Biological processi

Enzyme and pathway databases

UniPathwayiUPA00143

Names & Taxonomyi

Protein namesi
Submitted name:
Suppressor of cytokine signaling 8Imported
Gene namesi
Name:SOCS8Imported
OrganismiGasterosteus aculeatus (Three-spined stickleback)Imported
Taxonomic identifieri69293 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaPerciformesCottioideiGasterostealesGasterosteidaeGasterosteus

Subcellular locationi

Structurei

3D structure databases

ProteinModelPortaliB0L6U7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 166SH2InterPro annotationAdd BLAST119
Domaini161 – 209SOCS boxInterPro annotationAdd BLAST49

Keywords - Domaini

SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

HOVERGENiHBG002457

Family and domain databases

CDDicd10718 SH2_CIS, 1 hit
Gene3Di3.30.505.10, 1 hit
InterProiView protein in InterPro
IPR028425 CIS
IPR035887 CIS_SH2
IPR000980 SH2
IPR036860 SH2_dom_sf
IPR001496 SOCS_box
IPR036036 SOCS_box-like_dom_sf
PANTHERiPTHR44649 PTHR44649, 1 hit
PfamiView protein in Pfam
PF00017 SH2, 1 hit
PF07525 SOCS_box, 1 hit
PRINTSiPR00401 SH2DOMAIN
SMARTiView protein in SMART
SM00252 SH2, 1 hit
SM00253 SOCS, 1 hit
SM00969 SOCS_box, 1 hit
SUPFAMiSSF158235 SSF158235, 1 hit
SSF55550 SSF55550, 1 hit
PROSITEiView protein in PROSITE
PS50001 SH2, 1 hit
PS50225 SOCS, 1 hit

Sequencei

Sequence statusi: Complete.

B0L6U7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVARALTIFH HNEQGASCRP HPFPPPNDQA EDLRCITTTF QYLQTSGWYW
60 70 80 90 100
HSISASEARE ALFQQSEGTF LVRDSSHPQY MLALSVKTRC GPTSIRINYS
110 120 130 140 150
RGSFWLDSIS PSLPRLQSFP DVVSLIQHYK ASGHSPRDPA SDGIHPQTKP
160 170 180 190 200
EAAKDSVVPL KLSHPLHKPE AFPSLQHVTR LTINRHAHCP DQLPLPKTLL
210
RYLQEYPFTI
Length:210
Mass (Da):23,769
Last modified:March 18, 2008 - v1
Checksum:iCE027F9EB541F51E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF382413 mRNA Translation: ABQ53604.1
RefSeqiNP_001254610.1, NM_001267681.1
UniGeneiGac.15793

Genome annotation databases

GeneIDi100190872

Similar proteinsi

Entry informationi

Entry nameiB0L6U7_GASAC
AccessioniPrimary (citable) accession number: B0L6U7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 18, 2008
Last sequence update: March 18, 2008
Last modified: December 20, 2017
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
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Main funding by: National Institutes of Health