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B0KR47 (ASTD_PSEPG) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N-succinylglutamate 5-semialdehyde dehydrogenase
EC=1.2.1.71
Alternative name(s):
Succinylglutamic semialdehyde dehydrogenase
Short name=SGSD
Gene names
Name:astD
Ordered Locus Names:PputGB1_3983
OrganismPseudomonas putida (strain GB-1) [Complete proteome] [HAMAP]
Taxonomic identifier76869 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length487 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate By similarity. HAMAP MF_01174

Catalytic activity

N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N-succinyl-L-glutamate + NADH. HAMAP MF_01174

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 4/5. HAMAP MF_01174

Sequence similarities

Belongs to the aldehyde dehydrogenase family. AstD subfamily.

Ontologies

Keywords
   Biological processArginine metabolism
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processarginine catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionsuccinylglutamate-semialdehyde dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 487487N-succinylglutamate 5-semialdehyde dehydrogenase HAMAP MF_01174
PRO_1000085403

Regions

Nucleotide binding221 – 2266NAD By similarity

Sites

Active site2441 By similarity
Active site2781 By similarity

Sequences

Sequence LengthMass (Da)Tools
B0KR47 [UniParc].

Last modified March 18, 2008. Version 1.
Checksum: FFF2F0F9BFDB7435

FASTA48751,375
        10         20         30         40         50         60 
MTTHYIAGNW QAGQGETLQS LNPVTQAVVW QGQGAVASQV DAAVQAARQA FPAWAQLSLE 

        70         80         90        100        110        120 
ARIDVLEKFA AQLKVHAEAM AQCIGEETGK PLWESATEVT SMINKVAISV QSYRERTGEK 

       130        140        150        160        170        180 
SGPLADATAV LRHKPHGVVA VFGPYNFPGH LPNGHIVPAL LAGNCVVFKP SELTPKVAEL 

       190        200        210        220        230        240 
TVNCWIAAGL PAGVLNLVQG ARETGVALAA NPGIDGLFFT GSSRTGNLLH QQFAGRPDKI 

       250        260        270        280        290        300 
LALEMGGNNP LVVDEVKDLD AAVYTIIQSA FISAGQRCTC ARRLLVPQGS WGDALIARLV 

       310        320        330        340        350        360 
DVCKTITVGA FDEQPAPFMG SVISLQAARA LIAAQAELAA KGGVKLLEMT QPQADAALLT 

       370        380        390        400        410        420 
PGIIDVTAVD ERPDEEFFGP LLQVIRYVDF DAAIDEANNT QYGLAAGLLS DSRARYQYFW 

       430        440        450        460        470        480 
LRSRAGIVNW NKQLTGAASS APFGGVGASG NHRASAYYAA DYCAYPVASL ETASLALPAT 


LTPGVTL

« Hide

References

[1]"Complete sequence of Pseudomonas putida GB-1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Bruce D., Goodwin L., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., McCarthy J.K., Richardson P.
Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: GB-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000926 Genomic DNA. Translation: ABY99873.1.
RefSeqYP_001670209.1. NC_010322.1.

3D structure databases

ProteinModelPortalB0KR47.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0KR47.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5871783.
GenomeReviewsGene locus PputGB1_3983 in contig CP000926_GR.
KEGGppg:PputGB1_3983.
PATRIC19935039. VBIPsePut76638_3993.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG752218.
OMATHYIAGN.
ProtClustDBPRK09457.

Enzyme and pathway databases

BioCycPPUT76869:PPUTGB1_3983-MONOMER.

Family and domain databases

HAMAPMF_01174. Aldedh_AstD.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR017649. SuccinylGlu_semiald_DH_AstD.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK06447.
PANTHERPTHR11699:SF24. PTHR11699:SF24. 1 hit.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR03240. Arg_catab_astD. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameASTD_PSEPG
AccessionPrimary (citable) accession number: B0KR47
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 18, 2008
Last modified: January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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