Skip Header

Contribute Send feedback
Read comments (?) or add your own

B0KN19 (BETA_PSEPG) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Choline dehydrogenase
Short name=CDH
Short name=CHD
EC=1.1.99.1
Gene names
Name:betA
Ordered Locus Names:PputGB1_5115
OrganismPseudomonas putida (strain GB-1) [Complete proteome] [HAMAP]
Taxonomic identifier76869 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length565 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity. HAMAP MF_00750

Catalytic activity

Choline + acceptor = betaine aldehyde + reduced acceptor. HAMAP MF_00750

Cofactor

FAD By similarity. HAMAP MF_00750

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. HAMAP MF_00750

Sequence similarities

Belongs to the GMC oxidoreductase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 565565Choline dehydrogenase HAMAP MF_00750
PRO_1000083495

Regions

Nucleotide binding6 – 3530FAD Potential

Sites

Active site4751 By similarity

Sequences

Sequence LengthMass (Da)Tools
B0KN19 [UniParc].

Last modified March 18, 2008. Version 1.
Checksum: 4687D70667F89C98

FASTA56562,446
        10         20         30         40         50         60 
MSQEFDYIIV GAGSAGNTLA TRLTEDAGVT VLLLEAGGPD YRFDFRTQMP AALAFPLQGR 

        70         80         90        100        110        120 
RYNWAYETDP EPHMDGRRME CGRGKGLGGS SLINGMCYIR GNAMDFDGWA ELPGLQDWTY 

       130        140        150        160        170        180 
LDCLPYFRKA ETRDIGPNDY HGGEGPVSVA TPKAGNNPLF HAMVEAGVQA GYPRTEDLNG 

       190        200        210        220        230        240 
YQQEGFGPMD RSVTKNGRRS STARGYLDQA KKRPNLTIVT HALSDRVLFD GKRAVGVTYL 

       250        260        270        280        290        300 
VGDSEERVEA RARKEVIVSS GAIASPQLLQ RSGVGPRALL ESLDIPVVHD LPGVGENLQD 

       310        320        330        340        350        360 
HLELYLQYAC TQPVSLYPSL LWWNQPAIGA EWMFKGTGIG ASNQFEAGGF IRTRPEFKWP 

       370        380        390        400        410        420 
NIQYHFLPVA INYNGSNGVK EHGFQAHMGS MRSPARGRIQ AKSKDPRQHP SILFNYMSTE 

       430        440        450        460        470        480 
QDWQEFRDGI RLTREIMAQP ALDPYRGREI SPGADVQTDE QLDKFIREHA ETAFHPSCSC 

       490        500        510        520        530        540 
KMGTDDMAVV DGEGRVHGMK GLRVVDASIM PLIITGNLNA TTIMIAEKIS DKIRGRKPLP 

       550        560 
RSTAKYYVAG DAPVKGKPMR EVKQA

« Hide

References

[1]"Complete sequence of Pseudomonas putida GB-1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Bruce D., Goodwin L., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., McCarthy J.K., Richardson P.
Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: GB-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000926 Genomic DNA. Translation: ABZ01000.1.
RefSeqYP_001671335.1. NC_010322.1.

3D structure databases

ProteinModelPortalB0KN19.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0KN19.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5872930.
GenomeReviewsGene locus PputGB1_5115 in contig CP000926_GR.
KEGGppg:PputGB1_5115.
PATRIC19937309. VBIPsePut76638_5114.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG734713.
OMAKPLERAN.
ProtClustDBPRK02106.

Enzyme and pathway databases

BioCycPPUT76869:PPUTGB1_5115-MONOMER.

Family and domain databases

HAMAPMF_00750. Choline_dehydrogen.
[Tree]
InterProIPR011533. Choline_dehydrogenase.
IPR012132. GMC_OxRdtase.
IPR000172. GMC_OxRdtase_N.
IPR007867. GMC_OxRtase_C.
[Graphical view]
KOK00108.
PfamPF05199. GMC_oxred_C. 1 hit.
PF00732. GMC_oxred_N. 1 hit.
[Graphical view]
PIRSFPIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMsTIGR01810. BetA. 1 hit.
PROSITEPS00623. GMC_OXRED_1. 1 hit.
PS00624. GMC_OXRED_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBETA_PSEPG
AccessionPrimary (citable) accession number: B0KN19
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 18, 2008
Last modified: January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents