ID   BETB_PSEPG              Reviewed;         490 AA.
AC   B0KN18;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   18-MAR-2008, sequence version 1.
DT   16-JUN-2009, entry version 9.
DE   RecName: Full=Betaine aldehyde dehydrogenase;
DE            Short=BADH;
DE            EC=1.2.1.8;
GN   Name=betB; OrderedLocusNames=PputGB1_5114;
OS   Pseudomonas putida (strain GB-1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=76869;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA   Dalin E., Tice H., Pitluck S., Bruce D., Goodwin L., Chertkov O.,
RA   Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F.,
RA   Land M., Hauser L., Kyrpides N., Kim E., McCarthy J.K., Richardson P.;
RT   "Complete sequence of Pseudomonas putida GB-1.";
RL   Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Betaine aldehyde + NAD(+) + H(2)O = betaine +
CC       NADH.
CC   -!- PATHWAY: Amine and polyamine biosynthesis; betaine biosynthesis
CC       via choline pathway; betaine from betaine aldehyde: step 1/1.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
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DR   EMBL; CP000926; ABZ00999.1; -; Genomic_DNA.
DR   RefSeq; YP_001671334.1; -.
DR   GeneID; 5872929; -.
DR   GenomeReviews; CP000926_GR; PputGB1_5114.
DR   KEGG; ppg:PputGB1_5114; -.
DR   OMA; B0KN18; TLKEVTM.
DR   GO; GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:HAMAP.
DR   GO; GO:0019285; P:glycine betaine biosynthetic process from c...; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   HAMAP; MF_00804; -; 1.
DR   InterPro; IPR016160; Ald_DH_CS.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH.
DR   InterPro; IPR011264; Betaine_Ald_DH.
DR   Gene3D; G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
DR   PANTHER; PTHR11699; Aldehyde_dehyd; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   TIGRFAMs; TIGR01804; BADH; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Complete proteome; NAD; Oxidoreductase.
FT   CHAIN         1    490       Betaine aldehyde dehydrogenase.
FT                                /FTId=PRO_1000083710.
FT   NP_BIND     229    234       NAD (By similarity).
FT   ACT_SITE    252    252       By similarity.
FT   ACT_SITE    286    286       By similarity.
SQ   SEQUENCE   490 AA;  53041 MW;  90281237A7E278D9 CRC64;
     MARFGTQKLY IDGAYVDAGS DATFEAINPA TGEVLAHVQR ATEADVEKAV ESAERGQKVW
     AAMTAMQRSR ILRRAVDILR ERNDELAQLE TLDTGKSYSE TRYVDIVTGA DVLEYYAGLV
     PAIEGEQIPL RESSFVYTRR EPLGVTVGIG AWNYPIQIAL WKSAPALAAG NAMIFKPSEV
     TSLTTLKLAE IYTEAGLPNG VFNVLTGSGR EVGTWLTEHP RIEKVSFTGG TTTGKKVMAS
     ASSSSLKEVT MELGGKSPLI ICADADLDKA ADIAMMANFY SSGQVCTNGT RVFIPAEMKA
     AFEAKIAERV ARIRVGNPED ENTNFGPLVS FAHMENVLSY IAKGKEEGAR VLCGGERLTE
     GEFAKGAFVA PTVFTDCSDD MTIVKEEIFG PVMSILSYET EEEVIRRAND TEYGLAAGVC
     TNDITRAHRI IHKLEAGICW INAWGESPAE MPVGGYKQSG VGRENGVSSL AQYTRIKSVQ
     VELGGYNSVF
//