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B0KN18 (BETB_PSEPG) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Betaine aldehyde dehydrogenase
Short name=BADH
EC=1.2.1.8
Gene names
Name:betB
Ordered Locus Names:PputGB1_5114
OrganismPseudomonas putida (strain GB-1) [Complete proteome] [HAMAP]
Taxonomic identifier76869 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length490 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Betaine aldehyde + NAD+ + H2O = betaine + NADH. HAMAP MF_00804

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1. HAMAP MF_00804

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processbetaine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionbetaine-aldehyde dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 490490Betaine aldehyde dehydrogenase HAMAP MF_00804
PRO_1000083710

Regions

Nucleotide binding229 – 2346NAD By similarity

Sites

Active site2521 By similarity
Active site2861 By similarity

Sequences

Sequence LengthMass (Da)Tools
B0KN18 [UniParc].

Last modified March 18, 2008. Version 1.
Checksum: 90281237A7E278D9

FASTA49053,041
        10         20         30         40         50         60 
MARFGTQKLY IDGAYVDAGS DATFEAINPA TGEVLAHVQR ATEADVEKAV ESAERGQKVW 

        70         80         90        100        110        120 
AAMTAMQRSR ILRRAVDILR ERNDELAQLE TLDTGKSYSE TRYVDIVTGA DVLEYYAGLV 

       130        140        150        160        170        180 
PAIEGEQIPL RESSFVYTRR EPLGVTVGIG AWNYPIQIAL WKSAPALAAG NAMIFKPSEV 

       190        200        210        220        230        240 
TSLTTLKLAE IYTEAGLPNG VFNVLTGSGR EVGTWLTEHP RIEKVSFTGG TTTGKKVMAS 

       250        260        270        280        290        300 
ASSSSLKEVT MELGGKSPLI ICADADLDKA ADIAMMANFY SSGQVCTNGT RVFIPAEMKA 

       310        320        330        340        350        360 
AFEAKIAERV ARIRVGNPED ENTNFGPLVS FAHMENVLSY IAKGKEEGAR VLCGGERLTE 

       370        380        390        400        410        420 
GEFAKGAFVA PTVFTDCSDD MTIVKEEIFG PVMSILSYET EEEVIRRAND TEYGLAAGVC 

       430        440        450        460        470        480 
TNDITRAHRI IHKLEAGICW INAWGESPAE MPVGGYKQSG VGRENGVSSL AQYTRIKSVQ 

       490 
VELGGYNSVF

« Hide

References

[1]"Complete sequence of Pseudomonas putida GB-1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Bruce D., Goodwin L., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., McCarthy J.K., Richardson P.
Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: GB-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000926 Genomic DNA. Translation: ABZ00999.1.
RefSeqYP_001671334.1. NC_010322.1.

3D structure databases

ProteinModelPortalB0KN18.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0KN18.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5872929.
GenomeReviewsGene locus PputGB1_5114 in contig CP000926_GR.
KEGGppg:PputGB1_5114.
PATRIC19937307. VBIPsePut76638_5113.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG752218.
OMAGRENGLM.
ProtClustDBPRK13252.

Enzyme and pathway databases

BioCycPPUT76869:PPUTGB1_5114-MONOMER.

Family and domain databases

HAMAPMF_00804. BADH.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR011264. Betaine_Ald_DH.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK00130.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR01804. BADH. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBETB_PSEPG
AccessionPrimary (citable) accession number: B0KN18
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 18, 2008
Last modified: January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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