Reviewed, UniProtKB/Swiss-Prot B0KMR5 (NUDC_PSEPG)

Names and origin

Protein names

Recommended name:
    NADH pyrophosphatase
    EC=3.6.1.22

Gene names

Name:	nudC
Ordered Locus Names:	PputGB1_3628

Organism

Pseudomonas putida (strain GB-1) [Complete proteome] [HAMAP]

Taxonomic identifier

76869 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	276 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	NAD+ + H2O = AMP + NMN. HAMAP MF_00297
Cofactor	Divalent ions. Manganese or magnesium By similarity.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the Nudix hydrolase family. NudC subfamily.

Ontologies

Keywords
Ligand	Magnesium Manganese NAD
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	NAD+ diphosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP manganese ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 276	276	NADH pyrophosphatase HAMAP MF_00297		PRO_1000078948
Regions
	Motif	173 – 194	22	Nudix box HAMAP MF_00297

Sequences

	Sequence		Length	Mass (Da)
	B0KMR5-1 [UniParc]. Last modified March 18, 2008. Version 1. Checksum: 6E8BCE0CA8181CEA	FASTA	276	30,867
	10 20 30 40 50 60 MSARWTTAVL DPQITGGLAV ARSPDGFLVD ANGALFPRDW LKRQDLDVLC EHGIGHFDGQ 70 80 90 100 110 120 PVFLLELRSA TDVPGCSWRG LRAFMLEGDF DTYKVLGYAA QIGTWAREHR FCGSCGQAMT 130 140 150 160 170 180 QIRWERAMYC QPCDLRSYPR ISPSMIVLVT RGDEILLARS PRFVTGVYST LAGFAEPGES 190 200 210 220 230 240 AEDCLVREVR EEVAVEVQNI QYVGSQCWPF PHSMMLGFHA EYAGGDIVMQ PDEIEDAQWF 250 260 270 SVHDLPPLPA GRSIARYLID LYVARRLGLP EPVLPR

References

[1]

"Complete sequence of Pseudomonas putida GB-1." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Bruce D., Goodwin L., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., McCarthy J.K., Richardson P. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000926 Genomic DNA. Translation: ABY99519.1.
RefSeq	YP_001669855.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5871420.
GenomeReviews	Gene locus PputGB1_3628 in contig CP000926_GR.
KEGG	ppg:PputGB1_3628.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	B0KMR5. TWAREHR.
Family and domain databases
HAMAP	MF_00297. [Tree]
InterPro	IPR015375. NADH_PPase-like_N. IPR000086. NUDIX_hydrolase_core. IPR015376. Znr_NADH_PPase. [Graphical view]
Gene3D	G3DSA:3.90.79.10. NUDIX_hydrolase. 1 hit.
Pfam	PF00293. NUDIX. 1 hit. PF09296. NUDIX-like. 1 hit. PF09297. zf-NADH-PPase. 1 hit. [Graphical view]
PROSITE	PS00893. NUDIX. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NUDC_PSEPG

Accession

Primary (citable) accession number: B0KMR5

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	March 18, 2008
Last modified:	June 16, 2009
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)