ID   ADD_PSEPG               Reviewed;         315 AA.
AC   B0KLE3;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   18-MAR-2008, sequence version 1.
DT   16-JUN-2009, entry version 9.
DE   RecName: Full=Adenosine deaminase;
DE            EC=3.5.4.4;
DE   AltName: Full=Adenosine aminohydrolase;
GN   Name=add; OrderedLocusNames=PputGB1_0636;
OS   Pseudomonas putida (strain GB-1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=76869;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA   Dalin E., Tice H., Pitluck S., Bruce D., Goodwin L., Chertkov O.,
RA   Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F.,
RA   Land M., Hauser L., Kyrpides N., Kim E., McCarthy J.K., Richardson P.;
RT   "Complete sequence of Pseudomonas putida GB-1.";
RL   Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Adenosine + H(2)O = inosine + NH(3).
CC   -!- SIMILARITY: Belongs to the adenosine and AMP deaminases family.
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DR   EMBL; CP000926; ABY96547.1; -; Genomic_DNA.
DR   RefSeq; YP_001666883.1; -.
DR   GeneID; 5868382; -.
DR   GenomeReviews; CP000926_GR; PputGB1_0636.
DR   KEGG; ppg:PputGB1_0636; -.
DR   OMA; B0KLE3; LAQNSLD.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:HAMAP.
DR   GO; GO:0009168; P:purine ribonucleoside monophosphate biosynt...; IEA:HAMAP.
DR   HAMAP; MF_00540; -; 1.
DR   InterPro; IPR006650; A/AMP_deam_AS.
DR   InterPro; IPR001365; A/AMP_deaminase.
DR   InterPro; IPR006330; A_deaminase.
DR   PANTHER; PTHR11409; A/AMP_deaminase; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   TIGRFAMs; TIGR01430; aden_deam; 1.
DR   PROSITE; PS00485; A_DEAMINASE; FALSE_NEG.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase; Nucleotide metabolism.
FT   CHAIN         1    315       Adenosine deaminase.
FT                                /FTId=PRO_1000081928.
FT   ACT_SITE    194    194       Potential.
FT   ACT_SITE    242    242       Potential.
FT   ACT_SITE    275    275       Potential.
FT   ACT_SITE    276    276       Potential.
SQ   SEQUENCE   315 AA;  35981 MW;  4990D8817B557500 CRC64;
     MYDWLNALPK AELHLHLEGS LEPELLFALA ERNKIALPWN DVETLRGAYA FNNLQEFLDL
     YYQGADVLRT EQDFYDLTWA YLQRCKAQNV VHTEPFFDPQ THTDRGIAFE VVLNGISQAL
     KDGREQLGIS SGLILSFLRH LSEDEAHKTL DQALPFRDAF IAVGLDSSEM GHPPRKFQRV
     FDRARSEGFV AVAHAGEEGP PEYIWEALDL LKIKRIDHGV RAIEDERLMQ RIIEEQIPLT
     VCPLSNTKLC VFDHMSQHNI LDMLERGVKV TVNSDDPAYF GGYVTENFHA LHTHLGMTED
     QARRLAQNSL DARLI
//