Reviewed, UniProtKB/Swiss-Prot B0KLE3 (ADD_PSEPG)

Names and origin

Protein names

Recommended name:
    Adenosine deaminase
    EC=3.5.4.4
Alternative name(s):
    Adenosine aminohydrolase

Gene names

Name:	add
Ordered Locus Names:	PputGB1_0636

Organism

Pseudomonas putida (strain GB-1) [Complete proteome] [HAMAP]

Taxonomic identifier

76869 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	315 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Adenosine + H2O = inosine + NH3. HAMAP MF_00540
Sequence similarities	Belongs to the adenosine and AMP deaminases family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	purine ribonucleoside monophosphate biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	adenosine deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 315	315	Adenosine deaminase HAMAP MF_00540		PRO_1000081928
Sites
	Active site	194	1	Potential
	Active site	242	1	Potential
	Active site	275	1	Potential
	Active site	276	1	Potential

Sequences

	Sequence		Length	Mass (Da)
	B0KLE3-1 [UniParc]. Last modified March 18, 2008. Version 1. Checksum: 4990D8817B557500	FASTA	315	35,981
	10 20 30 40 50 60 MYDWLNALPK AELHLHLEGS LEPELLFALA ERNKIALPWN DVETLRGAYA FNNLQEFLDL 70 80 90 100 110 120 YYQGADVLRT EQDFYDLTWA YLQRCKAQNV VHTEPFFDPQ THTDRGIAFE VVLNGISQAL 130 140 150 160 170 180 KDGREQLGIS SGLILSFLRH LSEDEAHKTL DQALPFRDAF IAVGLDSSEM GHPPRKFQRV 190 200 210 220 230 240 FDRARSEGFV AVAHAGEEGP PEYIWEALDL LKIKRIDHGV RAIEDERLMQ RIIEEQIPLT 250 260 270 280 290 300 VCPLSNTKLC VFDHMSQHNI LDMLERGVKV TVNSDDPAYF GGYVTENFHA LHTHLGMTED 310 QARRLAQNSL DARLI

References

[1]

"Complete sequence of Pseudomonas putida GB-1." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Bruce D., Goodwin L., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., McCarthy J.K., Richardson P. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000926 Genomic DNA. Translation: ABY96547.1.
RefSeq	YP_001666883.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5868382.
GenomeReviews	Gene locus PputGB1_0636 in contig CP000926_GR.
KEGG	ppg:PputGB1_0636.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	B0KLE3. LAQNSLD.
Family and domain databases
HAMAP	MF_00540. [Tree]
InterPro	IPR006650. A/AMP_deam_AS. IPR001365. A/AMP_deaminase. IPR006330. A_deaminase. [Graphical view]
PANTHER	PTHR11409. A/AMP_deaminase. 1 hit.
Pfam	PF00962. A_deaminase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01430. aden_deam. 1 hit.
PROSITE	PS00485. A_DEAMINASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ADD_PSEPG

Accession

Primary (citable) accession number: B0KLE3

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	March 18, 2008
Last modified:	June 16, 2009
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)