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Protein

Cobalt-precorrin-5B C(1)-methyltransferase

Gene

cbiD

Organism
Pseudomonas putida (strain GB-1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.UniRule annotation

Catalytic activityi

Cobalt-precorrin-5B + S-adenosyl-L-methionine = cobalt-precorrin-6A + S-adenosyl-L-homocysteine.UniRule annotation

Pathwayi: adenosylcobalamin biosynthesis

This protein is involved in step 6 of the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route).UniRule annotation
Proteins known to be involved in the 10 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. no protein annotated in this organism
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. no protein annotated in this organism
  6. Cobalt-precorrin-5B C(1)-methyltransferase (cbiD)
  7. no protein annotated in this organism
  8. no protein annotated in this organism
  9. no protein annotated in this organism
  10. no protein annotated in this organism
This subpathway is part of the pathway adenosylcobalamin biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route), the pathway adenosylcobalamin biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processCobalamin biosynthesis
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciPPUT76869:G1GAZ-5025-MONOMER
UniPathwayiUPA00148; UER00227

Names & Taxonomyi

Protein namesi
Recommended name:
Cobalt-precorrin-5B C(1)-methyltransferaseUniRule annotation (EC:2.1.1.195UniRule annotation)
Alternative name(s):
Cobalt-precorrin-6A synthaseUniRule annotation
Gene namesi
Name:cbiDUniRule annotation
Ordered Locus Names:PputGB1_4887
OrganismiPseudomonas putida (strain GB-1)
Taxonomic identifieri76869 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002157 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000835931 – 364Cobalt-precorrin-5B C(1)-methyltransferaseAdd BLAST364

Interactioni

Protein-protein interaction databases

STRINGi76869.PputGB1_4887

Structurei

3D structure databases

ProteinModelPortaliB0KK08
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CbiD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EE8 Bacteria
COG1903 LUCA
HOGENOMiHOG000009126
KOiK02188
OMAiGGIFHTH

Family and domain databases

Gene3Di3.30.2110.10, 1 hit
HAMAPiMF_00787 CbiD, 1 hit
InterProiView protein in InterPro
IPR002748 CbiD
IPR036074 CbiD_sf
PANTHERiPTHR35863 PTHR35863, 1 hit
PfamiView protein in Pfam
PF01888 CbiD, 1 hit
PIRSFiPIRSF026782 CbiD, 1 hit
SUPFAMiSSF111342 SSF111342, 1 hit
TIGRFAMsiTIGR00312 cbiD, 1 hit

Sequencei

Sequence statusi: Complete.

B0KK08-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MREETREQPA PLRSGLTTGS CATATSLAAA RLLLSGETSD AVSITLPKGK
60 70 80 90 100
VVQMRLEFCR LAGESAEAGT LKDAGDDPDV THGALLYSQV RLLDEPSIRF
110 120 130 140 150
VAGSGVGTVT RPGLVLAVGE PAINPVPRRM ISEHLQRLAD ECGYFGGFEV
160 170 180 190 200
TVNVQGGEQL ALKTMNPRLG ILGGLSILGT SGIVRPFSCA AYIASIHQGI
210 220 230 240 250
DVAHTNGYTH IAACTGNASE DTMRRVYGLP EIALIEMGDF VGAVLKHLRK
260 270 280 290 300
VPVPRLTLCG GFGKISKLAA GHMDLHSRHS SIDLPQLAGW AADIGADAAL
310 320 330 340 350
QAAIIGANTS QQALALAHAA GIALGDAVCA HALAFARSVV PAQVQVEVFA
360
IDRQGGIVGR AGVQ
Length:364
Mass (Da):37,775
Last modified:March 18, 2008 - v1
Checksum:iD38681FDC1E6B8BB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000926 Genomic DNA Translation: ABZ00772.1
RefSeqiWP_012274403.1, NC_010322.1

Genome annotation databases

EnsemblBacteriaiABZ00772; ABZ00772; PputGB1_4887
KEGGippg:PputGB1_4887

Similar proteinsi

Entry informationi

Entry nameiCBID_PSEPG
AccessioniPrimary (citable) accession number: B0KK08
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 18, 2008
Last modified: March 28, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health