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Protein

Pyrroloquinoline-quinone synthase

Gene

pqqC

Organism
Pseudomonas putida (strain GB-1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.UniRule annotation

Catalytic activityi

6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O.UniRule annotation

Pathwayi: pyrroloquinoline quinone biosynthesis

This protein is involved in the pathway pyrroloquinoline quinone biosynthesis, which is part of Cofactor biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pyrroloquinoline quinone biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

PQQ biosynthesis

Enzyme and pathway databases

BioCyciPPUT76869:GIXB-416-MONOMER.
UniPathwayiUPA00539.

Names & Taxonomyi

Protein namesi
Recommended name:
Pyrroloquinoline-quinone synthaseUniRule annotation (EC:1.3.3.11UniRule annotation)
Alternative name(s):
Coenzyme PQQ synthesis protein CUniRule annotation
Pyrroloquinoline quinone biosynthesis protein CUniRule annotation
Gene namesi
Name:pqqCUniRule annotation
Ordered Locus Names:PputGB1_0407
OrganismiPseudomonas putida (strain GB-1)
Taxonomic identifieri76869 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002157 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 251251Pyrroloquinoline-quinone synthasePRO_1000082784Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi76869.PputGB1_0407.

Structurei

3D structure databases

ProteinModelPortaliB0KJ68.
SMRiB0KJ68. Positions 7-246.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PqqC family.UniRule annotation

Phylogenomic databases

eggNOGiENOG41086XE. Bacteria.
COG5424. LUCA.
HOGENOMiHOG000217947.
KOiK06137.
OMAiSRLDTWP.

Family and domain databases

Gene3Di1.20.910.10. 1 hit.
HAMAPiMF_00654. PQQ_syn_PqqC. 1 hit.
InterProiIPR016084. Haem_Oase-like_multi-hlx.
IPR011845. PQQ_synth_PqqC.
IPR004305. Thiaminase-2/PQQC.
[Graphical view]
PfamiPF03070. TENA_THI-4. 1 hit.
[Graphical view]
SUPFAMiSSF48613. SSF48613. 1 hit.
TIGRFAMsiTIGR02111. PQQ_syn_pqqC. 1 hit.

Sequencei

Sequence statusi: Complete.

B0KJ68-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDALPMSPA EFEQALRAKG AYYHIHHPYH VAMYQGRATR EQIQGWVANR
60 70 80 90 100
FYYQVNIPMK DAAILANCPD REVRREWIQR LLDHDGAPGE DGGIEAWLRL
110 120 130 140 150
GQAVGLDPDQ LRSQELVLPG VRFAVDAYVN FARRASWQEA ASSSLTELFA
160 170 180 190 200
PQIHQSRLDS WPQHYPWIDP AGYEYFRTRL GQARRDVEHG LAITLQHYTT
210 220 230 240 250
RAGQERMLEI LQFKLDILWS MLDAMSMAYE LNRPPYHSVT QDRVWHKGIT

L
Length:251
Mass (Da):29,061
Last modified:March 18, 2008 - v1
Checksum:iA9D301FD33C74E58
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000926 Genomic DNA. Translation: ABY96318.1.
RefSeqiWP_012270176.1. NC_010322.1.

Genome annotation databases

EnsemblBacteriaiABY96318; ABY96318; PputGB1_0407.
KEGGippg:PputGB1_0407.
PATRICi19927749. VBIPsePut76638_0416.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000926 Genomic DNA. Translation: ABY96318.1.
RefSeqiWP_012270176.1. NC_010322.1.

3D structure databases

ProteinModelPortaliB0KJ68.
SMRiB0KJ68. Positions 7-246.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi76869.PputGB1_0407.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABY96318; ABY96318; PputGB1_0407.
KEGGippg:PputGB1_0407.
PATRICi19927749. VBIPsePut76638_0416.

Phylogenomic databases

eggNOGiENOG41086XE. Bacteria.
COG5424. LUCA.
HOGENOMiHOG000217947.
KOiK06137.
OMAiSRLDTWP.

Enzyme and pathway databases

UniPathwayiUPA00539.
BioCyciPPUT76869:GIXB-416-MONOMER.

Family and domain databases

Gene3Di1.20.910.10. 1 hit.
HAMAPiMF_00654. PQQ_syn_PqqC. 1 hit.
InterProiIPR016084. Haem_Oase-like_multi-hlx.
IPR011845. PQQ_synth_PqqC.
IPR004305. Thiaminase-2/PQQC.
[Graphical view]
PfamiPF03070. TENA_THI-4. 1 hit.
[Graphical view]
SUPFAMiSSF48613. SSF48613. 1 hit.
TIGRFAMsiTIGR02111. PQQ_syn_pqqC. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPQQC_PSEPG
AccessioniPrimary (citable) accession number: B0KJ68
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 18, 2008
Last modified: September 7, 2016
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.