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B0KHX8

- IF2_PSEPG

UniProt

B0KHX8 - IF2_PSEPG

Protein

Translation initiation factor IF-2

Gene

infB

Organism
Pseudomonas putida (strain GB-1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (18 Mar 2008)
      Previous versions | rss
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    Functioni

    One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi351 – 3588GTPUniRule annotation
    Nucleotide bindingi397 – 4015GTPUniRule annotation
    Nucleotide bindingi451 – 4544GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: UniProtKB-HAMAP
    2. GTP binding Source: UniProtKB-KW
    3. translation initiation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Initiation factor

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciPPUT76869:GIXB-4793-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Translation initiation factor IF-2UniRule annotation
    Gene namesi
    Name:infBUniRule annotation
    Ordered Locus Names:PputGB1_4712
    OrganismiPseudomonas putida (strain GB-1)
    Taxonomic identifieri76869 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000002157: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 842842Translation initiation factor IF-2PRO_1000075614Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi76869.PputGB1_4712.

    Structurei

    3D structure databases

    ProteinModelPortaliB0KHX8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini342 – 509168tr-type GAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni351 – 3588G1By similarity
    Regioni376 – 3805G2By similarity
    Regioni397 – 4004G3By similarity
    Regioni451 – 4544G4By similarity
    Regioni487 – 4893G5By similarity

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0532.
    HOGENOMiHOG000076907.
    KOiK02519.
    OMAiNFECGLS.
    OrthoDBiEOG67HJSV.

    Family and domain databases

    Gene3Di3.40.50.10050. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_00100_B. IF_2_B.
    InterProiIPR009061. DNA-bd_dom_put.
    IPR000795. EF_GTP-bd_dom.
    IPR013575. IF2_assoc_dom_bac.
    IPR006847. IF2_N.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR000178. TF_IF2_bacterial-like.
    IPR015760. TIF_IF2.
    IPR023115. TIF_IF2_dom3.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view]
    PANTHERiPTHR23115:SF41. PTHR23115:SF41. 1 hit.
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF11987. IF-2. 1 hit.
    PF08364. IF2_assoc. 1 hit.
    PF04760. IF2_N. 2 hits.
    [Graphical view]
    SUPFAMiSSF46955. SSF46955. 1 hit.
    SSF50447. SSF50447. 2 hits.
    SSF52156. SSF52156. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00487. IF-2. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS51722. G_TR_2. 1 hit.
    PS01176. IF2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B0KHX8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTQVTVKELA QEVEAPVERL LQQMREAGLP HTDAGQVVTD NEKQTLLTHL    50
    KSSHKSKAEE PRKITLQRKT TSTLRVAGSK SISVEVRKKK VFVQRSPEEI 100
    QAEQKRELDE RRAAENAARD KVEAEVRQRN EEQARRQAAD SAVAAPAPAA 150
    KPEPAPAAAP APVVADAPAS EDAAARAAER KKDETRRNES RTRDDDRRRG 200
    EAPRVSIKVK VKEKEKAPTP RAAPRTTDEE SDGARRGRGG KGKLKKRNQH 250
    GFQNPTGPVI RDVTIGETIT VSELANQMSV KGAEVVKFMF KMGTPVTINQ 300
    VLDQETAQLI AEELGHKVTL VSDTALEDSL AESLKFEGQT ESRAPVVTVM 350
    GHVDHGKTSL LDYIRRAKVA AGEAGGITQH IGAYHVETDR GMVTFLDTPG 400
    HAAFTQMRAR GAKATDIVIL VVAADDGVMP QTREAVQHAK AAGVPLVVAV 450
    NKIDKPGADL DRIRNELSVE GVTSEDWGGD TPFVKVSAKM GTGVDELLEA 500
    VLLQAEILEL TATPTAPGRG VVVESRLDKG RGPVATILVQ DGTLRQGDMV 550
    LCGSNYGRVR AMLDENGKPV KEAGPSIPVE ILGLDGTPEA GDELSVVADE 600
    KKAREVALFR QGKYREVKLA RAHAGKLENI FETMGQEEKK TLNIVLKTDV 650
    RGSLEALQGS LGGLGNDEVQ VRVIGGGVGG ITESDANLAL ASNAVLFGFN 700
    VRADAGARKI VEQEGLDMRY YNVIYDIIED VKKALTGMLG SDVRENILGV 750
    AEVRDVFRSP KFGAIAGCMV IEGTVYRNRP IRVLRDDVVI FEGELESLRR 800
    FKDDASEVRS GMECGIGVKS YNDVKVGDKI EVFEKVQVAR TL 842
    Length:842
    Mass (Da):91,179
    Last modified:March 18, 2008 - v1
    Checksum:i22906692EB02EE55
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000926 Genomic DNA. Translation: ABZ00599.1.
    RefSeqiYP_001670934.1. NC_010322.1.

    Genome annotation databases

    EnsemblBacteriaiABZ00599; ABZ00599; PputGB1_4712.
    GeneIDi5872523.
    KEGGippg:PputGB1_4712.
    PATRICi19936515. VBIPsePut76638_4719.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000926 Genomic DNA. Translation: ABZ00599.1 .
    RefSeqi YP_001670934.1. NC_010322.1.

    3D structure databases

    ProteinModelPortali B0KHX8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 76869.PputGB1_4712.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABZ00599 ; ABZ00599 ; PputGB1_4712 .
    GeneIDi 5872523.
    KEGGi ppg:PputGB1_4712.
    PATRICi 19936515. VBIPsePut76638_4719.

    Phylogenomic databases

    eggNOGi COG0532.
    HOGENOMi HOG000076907.
    KOi K02519.
    OMAi NFECGLS.
    OrthoDBi EOG67HJSV.

    Enzyme and pathway databases

    BioCyci PPUT76869:GIXB-4793-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.10050. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_00100_B. IF_2_B.
    InterProi IPR009061. DNA-bd_dom_put.
    IPR000795. EF_GTP-bd_dom.
    IPR013575. IF2_assoc_dom_bac.
    IPR006847. IF2_N.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR000178. TF_IF2_bacterial-like.
    IPR015760. TIF_IF2.
    IPR023115. TIF_IF2_dom3.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view ]
    PANTHERi PTHR23115:SF41. PTHR23115:SF41. 1 hit.
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF11987. IF-2. 1 hit.
    PF08364. IF2_assoc. 1 hit.
    PF04760. IF2_N. 2 hits.
    [Graphical view ]
    SUPFAMi SSF46955. SSF46955. 1 hit.
    SSF50447. SSF50447. 2 hits.
    SSF52156. SSF52156. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00487. IF-2. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS51722. G_TR_2. 1 hit.
    PS01176. IF2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: GB-1.

    Entry informationi

    Entry nameiIF2_PSEPG
    AccessioniPrimary (citable) accession number: B0KHX8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: March 18, 2008
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3