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B0KHX8

- IF2_PSEPG

UniProt

B0KHX8 - IF2_PSEPG

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Protein

Translation initiation factor IF-2

Gene

infB

Organism
Pseudomonas putida (strain GB-1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi351 – 3588GTPUniRule annotation
Nucleotide bindingi397 – 4015GTPUniRule annotation
Nucleotide bindingi451 – 4544GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: UniProtKB-HAMAP
  2. GTP binding Source: UniProtKB-KW
  3. translation initiation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPPUT76869:GIXB-4793-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-2UniRule annotation
Gene namesi
Name:infBUniRule annotation
Ordered Locus Names:PputGB1_4712
OrganismiPseudomonas putida (strain GB-1)
Taxonomic identifieri76869 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002157: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 842842Translation initiation factor IF-2PRO_1000075614Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi76869.PputGB1_4712.

Structurei

3D structure databases

ProteinModelPortaliB0KHX8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini342 – 509168tr-type GAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni351 – 3588G1By similarity
Regioni376 – 3805G2By similarity
Regioni397 – 4004G3By similarity
Regioni451 – 4544G4By similarity
Regioni487 – 4893G5By similarity

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0532.
HOGENOMiHOG000076907.
KOiK02519.
OMAiNFECGLS.
OrthoDBiEOG67HJSV.

Family and domain databases

Gene3Di3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00100_B. IF_2_B.
InterProiIPR009061. DNA-bd_dom_put.
IPR000795. EF_GTP-bd_dom.
IPR013575. IF2_assoc_dom_bac.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PANTHERiPTHR23115:SF41. PTHR23115:SF41. 1 hit.
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF11987. IF-2. 1 hit.
PF08364. IF2_assoc. 1 hit.
PF04760. IF2_N. 2 hits.
[Graphical view]
SUPFAMiSSF46955. SSF46955. 1 hit.
SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0KHX8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTQVTVKELA QEVEAPVERL LQQMREAGLP HTDAGQVVTD NEKQTLLTHL
60 70 80 90 100
KSSHKSKAEE PRKITLQRKT TSTLRVAGSK SISVEVRKKK VFVQRSPEEI
110 120 130 140 150
QAEQKRELDE RRAAENAARD KVEAEVRQRN EEQARRQAAD SAVAAPAPAA
160 170 180 190 200
KPEPAPAAAP APVVADAPAS EDAAARAAER KKDETRRNES RTRDDDRRRG
210 220 230 240 250
EAPRVSIKVK VKEKEKAPTP RAAPRTTDEE SDGARRGRGG KGKLKKRNQH
260 270 280 290 300
GFQNPTGPVI RDVTIGETIT VSELANQMSV KGAEVVKFMF KMGTPVTINQ
310 320 330 340 350
VLDQETAQLI AEELGHKVTL VSDTALEDSL AESLKFEGQT ESRAPVVTVM
360 370 380 390 400
GHVDHGKTSL LDYIRRAKVA AGEAGGITQH IGAYHVETDR GMVTFLDTPG
410 420 430 440 450
HAAFTQMRAR GAKATDIVIL VVAADDGVMP QTREAVQHAK AAGVPLVVAV
460 470 480 490 500
NKIDKPGADL DRIRNELSVE GVTSEDWGGD TPFVKVSAKM GTGVDELLEA
510 520 530 540 550
VLLQAEILEL TATPTAPGRG VVVESRLDKG RGPVATILVQ DGTLRQGDMV
560 570 580 590 600
LCGSNYGRVR AMLDENGKPV KEAGPSIPVE ILGLDGTPEA GDELSVVADE
610 620 630 640 650
KKAREVALFR QGKYREVKLA RAHAGKLENI FETMGQEEKK TLNIVLKTDV
660 670 680 690 700
RGSLEALQGS LGGLGNDEVQ VRVIGGGVGG ITESDANLAL ASNAVLFGFN
710 720 730 740 750
VRADAGARKI VEQEGLDMRY YNVIYDIIED VKKALTGMLG SDVRENILGV
760 770 780 790 800
AEVRDVFRSP KFGAIAGCMV IEGTVYRNRP IRVLRDDVVI FEGELESLRR
810 820 830 840
FKDDASEVRS GMECGIGVKS YNDVKVGDKI EVFEKVQVAR TL
Length:842
Mass (Da):91,179
Last modified:March 18, 2008 - v1
Checksum:i22906692EB02EE55
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000926 Genomic DNA. Translation: ABZ00599.1.
RefSeqiWP_012274244.1. NC_010322.1.
YP_001670934.1. NC_010322.1.

Genome annotation databases

EnsemblBacteriaiABZ00599; ABZ00599; PputGB1_4712.
GeneIDi5872523.
KEGGippg:PputGB1_4712.
PATRICi19936515. VBIPsePut76638_4719.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000926 Genomic DNA. Translation: ABZ00599.1 .
RefSeqi WP_012274244.1. NC_010322.1.
YP_001670934.1. NC_010322.1.

3D structure databases

ProteinModelPortali B0KHX8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 76869.PputGB1_4712.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABZ00599 ; ABZ00599 ; PputGB1_4712 .
GeneIDi 5872523.
KEGGi ppg:PputGB1_4712.
PATRICi 19936515. VBIPsePut76638_4719.

Phylogenomic databases

eggNOGi COG0532.
HOGENOMi HOG000076907.
KOi K02519.
OMAi NFECGLS.
OrthoDBi EOG67HJSV.

Enzyme and pathway databases

BioCyci PPUT76869:GIXB-4793-MONOMER.

Family and domain databases

Gene3Di 3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00100_B. IF_2_B.
InterProi IPR009061. DNA-bd_dom_put.
IPR000795. EF_GTP-bd_dom.
IPR013575. IF2_assoc_dom_bac.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view ]
PANTHERi PTHR23115:SF41. PTHR23115:SF41. 1 hit.
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF11987. IF-2. 1 hit.
PF08364. IF2_assoc. 1 hit.
PF04760. IF2_N. 2 hits.
[Graphical view ]
SUPFAMi SSF46955. SSF46955. 1 hit.
SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GB-1.

Entry informationi

Entry nameiIF2_PSEPG
AccessioniPrimary (citable) accession number: B0KHX8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 18, 2008
Last modified: November 26, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3