B0KHW6 (G6PI_PSEPG) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glucose-6-phosphate isomerase
Short name=GPI
EC=5.3.1.9

Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI

Gene names

Name:	pgi
Ordered Locus Names:	PputGB1_4700

Organism

Pseudomonas putida (strain GB-1) [Complete proteome] [HAMAP]

Taxonomic identifier

76869 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › Pseudomonas putida group › Pseudomonas putida

Protein attributes

Sequence length	554 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473
Pathway	Carbohydrate biosynthesis; gluconeogenesis. HAMAP-Rule MF_00473 Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00473.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	gluconeogenesis Inferred from electronic annotation. Source: UniProtKB-HAMAP glycolytic process Inferred from electronic annotation. Source: UniProtKB-HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: UniProtKB-HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 554	554	Glucose-6-phosphate isomerase HAMAP-Rule MF_00473		PRO_1000081245
Sites
	Active site	359	1	Proton donor By similarity
	Active site	390	1	By similarity
	Active site	518	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	B0KHW6 [UniParc]. Last modified March 18, 2008. Version 1. Checksum: 07D99624F3460D66	FASTA	554	61,383
	10 20 30 40 50 60 MAYYRTPHDV TALPAWQALQ QHRDAMQGFS MREAFAADAQ RFDQFSLSCC GLFLDYSKNL 70 80 90 100 110 120 ITEQSRDLLV NLANEVGLQD AIKSMFAGEI INASEGRPVL HTALRRPVGD KLSVNGVNVM 130 140 150 160 170 180 PEVHKVLNQI TELVGRIHDG LWRGYSEKPI TDVVNIGIGG SFLGPELVSE ALLPYAQRGV 190 200 210 220 230 240 RCHYLANIDG SEFHELSANL RAETTLFIVS SKSFNTLETL KNAMAARTWY LAQGGSEAEL 250 260 270 280 290 300 YRHFIAVSSN KAAAVAFGIR EENIFPMWDW VGGRYSLWSA IGLPIALAIG TANFKELLSG 310 320 330 340 350 360 AYTMDQHFQT APFDKNMPVL LALLGVWYGN FWGANSHAIL PYDHYLRNIT KHLQQLDMES 370 380 390 400 410 420 NGKSVLQDGT PVKTDTGPVI WGGVGCNGQH AYHQLLHQGT QLIPADFIVP VVSFNPVADH 430 440 450 460 470 480 HQWLYANCLS QSQALMLGKT REEAEAELRG KGLNEADIEK LAPHKVIPGN RPSNTLVVER 490 500 510 520 530 540 ISPRRLGALV AMYEHKVFVQ SVIWGINAFD QWGVELGKEL GKGVYQRLVG SLEESAEDGS 550 TQGLINYFRG RHRG

References

[1]

"Complete sequence of Pseudomonas putida GB-1." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Bruce D., Goodwin L., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., McCarthy J.K., Richardson P. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GB-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000926 Genomic DNA. Translation: ABZ00587.1.
RefSeq	YP_001670922.1. NC_010322.1.
3D structure databases
ProteinModelPortal	B0KHW6.
ModBase	Search...
MobiDB	Search...
Protein-protein interaction databases
STRING	76869.PputGB1_4700.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABZ00587; ABZ00587; PputGB1_4700.
GeneID	5872511.
KEGG	ppg:PputGB1_4700.
PATRIC	19936493. VBIPsePut76638_4708.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0166.
HOGENOM	HOG000261370.
KO	K01810.
OMA	NCHFVAN.
OrthoDB	EOG64R61J.
Enzyme and pathway databases
BioCyc	PPUT76869:GIXB-4781-MONOMER.
UniPathway	UPA00109; UER00181. UPA00138.
Family and domain databases
Gene3D	1.10.1390.10. 1 hit.
HAMAP	MF_00473. G6P_isomerase.
InterPro	IPR001672. G6P_Isomerase. IPR023096. G6P_Isomerase_C. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
PANTHER	PTHR11469. PTHR11469. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI_PSEPG

Accession

Primary (citable) accession number: B0KHW6

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	March 18, 2008
Last modified:	June 11, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program