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B0KHW6 (G6PI_PSEPG) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase
Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:PputGB1_4700
OrganismPseudomonas putida (strain GB-1) [Complete proteome] [HAMAP]
Taxonomic identifier76869 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas ›

Protein attributes

Sequence length554 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP-Rule MF_00473

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 554554Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_1000081245

Sites

Active site3591Proton donor By similarity
Active site3901 By similarity
Active site5181 By similarity

Sequences

Sequence LengthMass (Da)Tools
B0KHW6 [UniParc].

Last modified March 18, 2008. Version 1.
Checksum: 07D99624F3460D66

FASTA55461,383
        10         20         30         40         50         60 
MAYYRTPHDV TALPAWQALQ QHRDAMQGFS MREAFAADAQ RFDQFSLSCC GLFLDYSKNL 

        70         80         90        100        110        120 
ITEQSRDLLV NLANEVGLQD AIKSMFAGEI INASEGRPVL HTALRRPVGD KLSVNGVNVM 

       130        140        150        160        170        180 
PEVHKVLNQI TELVGRIHDG LWRGYSEKPI TDVVNIGIGG SFLGPELVSE ALLPYAQRGV 

       190        200        210        220        230        240 
RCHYLANIDG SEFHELSANL RAETTLFIVS SKSFNTLETL KNAMAARTWY LAQGGSEAEL 

       250        260        270        280        290        300 
YRHFIAVSSN KAAAVAFGIR EENIFPMWDW VGGRYSLWSA IGLPIALAIG TANFKELLSG 

       310        320        330        340        350        360 
AYTMDQHFQT APFDKNMPVL LALLGVWYGN FWGANSHAIL PYDHYLRNIT KHLQQLDMES 

       370        380        390        400        410        420 
NGKSVLQDGT PVKTDTGPVI WGGVGCNGQH AYHQLLHQGT QLIPADFIVP VVSFNPVADH 

       430        440        450        460        470        480 
HQWLYANCLS QSQALMLGKT REEAEAELRG KGLNEADIEK LAPHKVIPGN RPSNTLVVER 

       490        500        510        520        530        540 
ISPRRLGALV AMYEHKVFVQ SVIWGINAFD QWGVELGKEL GKGVYQRLVG SLEESAEDGS 

       550 
TQGLINYFRG RHRG

« Hide

References

[1]"Complete sequence of Pseudomonas putida GB-1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Bruce D., Goodwin L., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., McCarthy J.K., Richardson P.
Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: GB-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000926 Genomic DNA. Translation: ABZ00587.1.
RefSeqYP_001670922.1. NC_010322.1.

3D structure databases

ProteinModelPortalB0KHW6.
ModBaseSearch...

Protein-protein interaction databases

STRING76869.PputGB1_4700.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABZ00587; ABZ00587; PputGB1_4700.
GeneID5872511.
KEGGppg:PputGB1_4700.
PATRIC19936493. VBIPsePut76638_4708.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMALKMHFVS.
OrthoDBEOG64R61J.
ProtClustDBPRK00179.

Enzyme and pathway databases

BioCycPPUT76869:GIXB-4781-MONOMER.
UniPathwayUPA00109; UER00181.
UPA00138.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_PSEPG
AccessionPrimary (citable) accession number: B0KHW6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 18, 2008
Last modified: November 13, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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