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B0K2U0 (TRPF_THEPX) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-(5'-phosphoribosyl)anthranilate isomerase

Short name=PRAI
EC=5.3.1.24
Gene names
Name:trpF
Ordered Locus Names:Teth514_1865
OrganismThermoanaerobacter sp. (strain X514) [Complete proteome] [HAMAP]
Taxonomic identifier399726 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeThermoanaerobacter

Protein attributes

Sequence length203 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135

Sequence similarities

Belongs to the TrpF family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
Tryptophan biosynthesis
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtryptophan biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionphosphoribosylanthranilate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 203203N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135
PRO_1000095946

Sequences

Sequence LengthMass (Da)Tools
B0K2U0 [UniParc].

Last modified March 18, 2008. Version 1.
Checksum: CA3E8CAA83791AE6

FASTA20323,294
        10         20         30         40         50         60 
MVKVKICGLR RKEDIEYANE LKPDYVGFVF AKSKRQIEVE QALDLISLLD KEIKTVGVFV 

        70         80         90        100        110        120 
NEPVENALKI AQTLNLDVLQ FHGDETQDYI DNFKNFTVWK AIRIKDKEDL EKTKEFKVNS 

       130        140        150        160        170        180 
FVFDTLTKNE YGGTGKTFNW EVLKGFELNV PIILAGGLNE NNVEEAIRIV NPYAVDVSSG 

       190        200 
VETEGYKDFK KMKSFIEKVR GIR 

« Hide

References

[1]"Complete sequence of Thermoanaerobacter sp. X514."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Bruce D., Goodwin L., Saunders E., Brettin T., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Kim E., Hemme C., Fields M.W., He Z., Zhou J., Richardson P.
Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: X514.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000923 Genomic DNA. Translation: ABY93145.1.
RefSeqYP_001663481.1. NC_010320.1.

3D structure databases

ProteinModelPortalB0K2U0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING399726.Teth514_1865.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABY93145; ABY93145; Teth514_1865.
GeneID5877756.
KEGGtex:Teth514_1865.
PATRIC23893414. VBITheSp86957_1931.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0135.
HOGENOMHOG000161598.
KOK01817.
OMAFVNASRC.
OrthoDBEOG6N94DF.
ProtClustDBCLSK883395.

Enzyme and pathway databases

BioCycTSP399726:GHCK-1911-MONOMER.
UniPathwayUPA00035; UER00042.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00135. PRAI.
InterProIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRPF_THEPX
AccessionPrimary (citable) accession number: B0K2U0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: March 18, 2008
Last modified: February 19, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways