B0JX00 (SURE_MICAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	MAE_50650

Organism

Microcystis aeruginosa (strain NIES-843) [Complete proteome] [HAMAP]

Taxonomic identifier

449447 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Microcystis

Protein attributes

Sequence length	270 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 270	270	5'-nucleotidase surE HAMAP MF_00060		PRO_1000075032
Sites
	Metal binding	14	1	Divalent metal cation By similarity
	Metal binding	15	1	Divalent metal cation By similarity
	Metal binding	46	1	Divalent metal cation By similarity
	Metal binding	104	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	B0JX00 [UniParc]. Last modified March 18, 2008. Version 1. Checksum: 314F080548AFE699	FASTA	270	29,383
	10 20 30 40 50 60 MTSDRPLKLL ISNDDGISAL GVRTLANTLA TAGHQVTVVC PDGERSATGH GLTLHHPIRA 70 80 90 100 110 120 EQVEGIFHPD VIAWSCSGTP ADSVKFALSA VLKERPDLVL AGINHGSNLG TDILYSGTVS 130 140 150 160 170 180 AALEGLIEGI PSIAFSLASF KACDFQPAAD FALTLVRKVA LNPFPLPTLL NVNVPPVSSG 190 200 210 220 230 240 EIKGVKITRQ GLRHYEETFE KRLDPRGKSY YWLIGEVVED IEQPDYTHLP PEVPTDVRAI 250 260 270 GENFITITPL QYNLTDVQGF QHLHRNSWFD

References

[1]

"Complete genomic structure of the bloom-forming toxic cyanobacterium Microcystis aeruginosa NIES-843." Kaneko T., Nakajima N., Okamoto S., Suzuki I., Tanabe Y., Tamaoki M., Nakamura Y., Kasai F., Watanabe A., Kawashima K., Kishida Y., Ono A., Shimizu Y., Takahashi C., Minami C., Fujishiro T., Kohara M., Katoh M. , Nakazaki N., Nakayama S., Yamada M., Tabata S., Watanabe M.M. DNA Res. 14:247-256(2007) [PubMed: 18192279] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NIES-843.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009552 Genomic DNA. Translation: BAG04887.1.
RefSeq	YP_001660079.1. NC_010296.1.
3D structure databases
ProteinModelPortal	B0JX00.
ModBase	Search...
Protein-protein interaction databases
STRING	B0JX00.
Proteomic databases
PRIDE	B0JX00.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5865901.
GenomeReviews	Gene locus MAE_50650 in contig AP009552_GR.
KEGG	mar:MAE_50650.
PATRIC	22634603. VBIMicAer59304_4606.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG600532.
OMA	DCVKMGI.
PhylomeDB	B0JX00.
ProtClustDB	PRK00346.
Enzyme and pathway databases
BioCyc	MAER449447:MAE_50650-MONOMER.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_MICAN

Accession

Primary (citable) accession number: B0JX00

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	March 18, 2008
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program