B0JW73 (B0JW73_MICAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA 1 HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase 1 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 1 HAMAP MF_01401

Gene names

Name:	msrA1 HAMAP MF_01401
Ordered Locus Names:	MAE_17310

Organism

Microcystis aeruginosa (strain NIES-843) [Complete proteome] [HAMAP]

Taxonomic identifier

449447 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Microcystis

Protein attributes

Sequence length	220 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 SAAS SAAS002569
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	56	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	B0JW73 [UniParc]. Last modified March 18, 2008. Version 1. Checksum: 8D31C91F9E964712	FASTA	220	24,439
	10 20 30 40 50 60 MVLFGFGKKL TLPTAREALP GRSEKMPVPS THYVNGHPLQ PPFPGGMESA MFGLGCFWGA 70 80 90 100 110 120 ERKFWQLEGV YTTAVGYAAG ITPNPTYQEV CTGMTGHNEV VLVVYDPSVI SYEQLLKVFW 130 140 150 160 170 180 ESHNPTQGMR QGNDTGTQYR SGIYTYSPQQ KQLAEKSRSI YQEALNKANY GQITTEILDA 190 200 210 220 PEFYYAEVYH QQYLAKNPGG YCGLGGTKVE CPLALDLKLN

References

[1]

"Complete genomic structure of the bloom-forming toxic cyanobacterium Microcystis aeruginosa NIES-843." Kaneko T., Nakajima N., Okamoto S., Suzuki I., Tanabe Y., Tamaoki M., Nakamura Y., Kasai F., Watanabe A., Kawashima K., Kishida Y., Ono A., Shimizu Y., Takahashi C., Minami C., Fujishiro T., Kohara M., Katoh M. , Nakazaki N., Nakayama S., Yamada M., Tabata S., Watanabe M.M. DNA Res. 14:247-256(2007) [PubMed: 18192279] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009552 Genomic DNA. Translation: BAG01553.1.
RefSeq	YP_001656745.1. NC_010296.1.
3D structure databases
ProteinModelPortal	B0JW73.
SMR	B0JW73. Positions 14-212.
ModBase	Search...
Protein-protein interaction databases
STRING	B0JW73.
Proteomic databases
PRIDE	B0JW73.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5862532.
GenomeReviews	Gene locus MAE_17310 in contig AP009552_GR.
KEGG	mar:MAE_17310.
PATRIC	22628499. VBIMicAer59304_1586.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG748152.
OMA	QETSFEQ.
PhylomeDB	B0JW73.
ProtClustDB	PRK00058.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B0JW73_MICAN

Accession

Primary (citable) accession number: B0JW73

Entry history

Integrated into UniProtKB/TrEMBL:	March 18, 2008
Last sequence update:	March 18, 2008
Last modified:	December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)