B0JV88 (COMB_MICAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable 2-phosphosulfolactate phosphatase
EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	MAE_16000

Organism

Microcystis aeruginosa (strain NIES-843) [Complete proteome] [HAMAP]

Taxonomic identifier

449447 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Microcystis

Protein attributes

Sequence length	241 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity. HAMAP MF_00490
Sequence similarities	Belongs to the ComB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 241	241	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_1000126228

Sequences

	Sequence		Length	Mass (Da)
	B0JV88 [UniParc]. Last modified March 18, 2008. Version 1. Checksum: 6E7DE347F69CC6F3	FASTA	241	26,382
	10 20 30 40 50 60 MQVFIYHTPE LTPVHTLPDC AVVIDVLRAT TTIATALNAG AEAVQTFSDL KTLMQVSDTW 70 80 90 100 110 120 QPEKRLRAGE RGGAKVEGCD LGNSPLDCTP DLMKGRRLFI STTNGTRALQ RVEESPIVIT 130 140 150 160 170 180 AAMINRQAAV NYLLDKQPDT VWIVGSGWEG GYSLEDTACA GAIADALQEQ SGQMAIGNDE 190 200 210 220 230 240 VIASIALYRQ WQNDLLGMFH SCSHGQRLLR LHCQEDLKYC ANIDSLDVLP IQKEPSILVK L

References

[1]

"Complete genomic structure of the bloom-forming toxic cyanobacterium Microcystis aeruginosa NIES-843." Kaneko T., Nakajima N., Okamoto S., Suzuki I., Tanabe Y., Tamaoki M., Nakamura Y., Kasai F., Watanabe A., Kawashima K., Kishida Y., Ono A., Shimizu Y., Takahashi C., Minami C., Fujishiro T., Kohara M., Katoh M. , Nakazaki N., Nakayama S., Yamada M., Tabata S., Watanabe M.M. DNA Res. 14:247-256(2007) [PubMed: 18192279] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NIES-843.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009552 Genomic DNA. Translation: BAG01422.1.
RefSeq	YP_001656614.1. NC_010296.1.
3D structure databases
ProteinModelPortal	B0JV88.
ModBase	Search...
Protein-protein interaction databases
STRING	B0JV88.
Proteomic databases
PRIDE	B0JV88.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5862400.
GenomeReviews	Gene locus MAE_16000 in contig AP009552_GR.
KEGG	mar:MAE_16000.
PATRIC	22628261. VBIMicAer59304_1468.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG633644.
OMA	DFICSGY.
PhylomeDB	B0JV88.
ProtClustDB	PRK00886.
Enzyme and pathway databases
BioCyc	MAER449447:MAE_16000-MONOMER.
Family and domain databases
HAMAP	MF_00490. ComB. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. IPR022995. Pase_ComB. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
KO	K05979.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
SUPFAM	SSF142823. SSF142823. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_MICAN

Accession

Primary (citable) accession number: B0JV88

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	March 18, 2008
Last modified:	January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program