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B0JUK5

- TRMB_MICAN

UniProt

B0JUK5 - TRMB_MICAN

Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene

trmB

Organism
Microcystis aeruginosa (strain NIES-843)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 1 (18 Mar 2008)
      Previous versions | rss
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    • Comment

    Functioni

    Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.UniRule annotation

    Catalytic activityi

    S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei40 – 401S-adenosyl-L-methionineUniRule annotation
    Binding sitei65 – 651S-adenosyl-L-methionineUniRule annotation
    Binding sitei92 – 921S-adenosyl-L-methionineUniRule annotation
    Active sitei118 – 1181By similarity
    Binding sitei118 – 1181S-adenosyl-L-methionineUniRule annotation
    Binding sitei122 – 1221SubstrateUniRule annotation
    Binding sitei154 – 1541SubstrateUniRule annotation

    GO - Molecular functioni

    1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    S-adenosyl-L-methionine

    Enzyme and pathway databases

    BioCyciMAER449447:GHO8-4665-MONOMER.
    UniPathwayiUPA00989.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation (EC:2.1.1.33UniRule annotation)
    Alternative name(s):
    tRNA (guanine(46)-N(7))-methyltransferaseUniRule annotation
    tRNA(m7G46)-methyltransferaseUniRule annotation
    Gene namesi
    Name:trmBUniRule annotation
    Ordered Locus Names:MAE_46310
    OrganismiMicrocystis aeruginosa (strain NIES-843)
    Taxonomic identifieri449447 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesMicrocystis
    ProteomesiUP000001510: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 211211tRNA (guanine-N(7)-)-methyltransferasePRO_1000084444Add
    BLAST

    Proteomic databases

    PRIDEiB0JUK5.

    Interactioni

    Protein-protein interaction databases

    STRINGi449447.MAE_46310.

    Structurei

    3D structure databases

    ProteinModelPortaliB0JUK5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0220.
    HOGENOMiHOG000237936.
    KOiK03439.
    OMAiRVTIQFP.
    OrthoDBiEOG6K6VBC.

    Family and domain databases

    Gene3Di3.40.50.150. 1 hit.
    HAMAPiMF_01057. tRNA_methyltr_TrmB.
    InterProiIPR029063. SAM-dependent_MTases-like.
    IPR003358. tRNA_(Gua-N-7)_MeTrfase.
    [Graphical view]
    PfamiPF02390. Methyltransf_4. 1 hit.
    [Graphical view]
    SUPFAMiSSF53335. SSF53335. 1 hit.
    TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
    PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B0JUK5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKVRVRQHV NPLSHKYRHP IAPPDWNQVY QDMTQPLHLD IGCARGKFLL    50
    QMAQVEPEIN FLGIEIRQPL VIEANQERER LGLSNLAFVF GNMNVAPEIL 100
    LQSLPADKLF WVSIQFPDPW FKQRHSKRRV VQPELVIALA KYMVAGGWVF 150
    LQSDVESIAL EMTERFQAHP HFVRQHQTPW LEENIFPVPT EREKSTYNKG 200
    QPVYRSLFRV R 211
    Length:211
    Mass (Da):24,716
    Last modified:March 18, 2008 - v1
    Checksum:i2AD780A755F725F2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP009552 Genomic DNA. Translation: BAG04453.1.
    RefSeqiWP_012267192.1. NC_010296.1.
    YP_001659645.1. NC_010296.1.

    Genome annotation databases

    EnsemblBacteriaiBAG04453; BAG04453; MAE_46310.
    GeneIDi5865461.
    KEGGimar:MAE_46310.
    PATRICi22633797. VBIMicAer59304_4209.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP009552 Genomic DNA. Translation: BAG04453.1 .
    RefSeqi WP_012267192.1. NC_010296.1.
    YP_001659645.1. NC_010296.1.

    3D structure databases

    ProteinModelPortali B0JUK5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 449447.MAE_46310.

    Proteomic databases

    PRIDEi B0JUK5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAG04453 ; BAG04453 ; MAE_46310 .
    GeneIDi 5865461.
    KEGGi mar:MAE_46310.
    PATRICi 22633797. VBIMicAer59304_4209.

    Phylogenomic databases

    eggNOGi COG0220.
    HOGENOMi HOG000237936.
    KOi K03439.
    OMAi RVTIQFP.
    OrthoDBi EOG6K6VBC.

    Enzyme and pathway databases

    UniPathwayi UPA00989 .
    BioCyci MAER449447:GHO8-4665-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.150. 1 hit.
    HAMAPi MF_01057. tRNA_methyltr_TrmB.
    InterProi IPR029063. SAM-dependent_MTases-like.
    IPR003358. tRNA_(Gua-N-7)_MeTrfase.
    [Graphical view ]
    Pfami PF02390. Methyltransf_4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53335. SSF53335. 1 hit.
    TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
    PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NIES-843.

    Entry informationi

    Entry nameiTRMB_MICAN
    AccessioniPrimary (citable) accession number: B0JUK5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: March 18, 2008
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3