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B0JTF5

- PUR5_MICAN

UniProt

B0JTF5 - PUR5_MICAN

Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Microcystis aeruginosa (strain NIES-843)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (18 Mar 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Ligase

    Keywords - Biological processi

    Purine biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMAER449447:GHO8-4470-MONOMER.
    UniPathwayiUPA00074; UER00129.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
    Alternative name(s):
    AIR synthaseUniRule annotation
    AIRSUniRule annotation
    Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
    Gene namesi
    Name:purMUniRule annotation
    Ordered Locus Names:MAE_44360
    OrganismiMicrocystis aeruginosa (strain NIES-843)
    Taxonomic identifieri449447 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesMicrocystis
    ProteomesiUP000001510: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 341341Phosphoribosylformylglycinamidine cyclo-ligasePRO_1000083461Add
    BLAST

    Proteomic databases

    PaxDbiB0JTF5.
    PRIDEiB0JTF5.

    Interactioni

    Protein-protein interaction databases

    STRINGi449447.MAE_44360.

    Structurei

    3D structure databases

    ProteinModelPortaliB0JTF5.
    SMRiB0JTF5. Positions 1-338.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the AIR synthase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0150.
    HOGENOMiHOG000229090.
    KOiK01933.
    OMAiEFEMYRT.
    OrthoDBiEOG61CM1V.

    Family and domain databases

    Gene3Di3.30.1330.10. 1 hit.
    3.90.650.10. 1 hit.
    HAMAPiMF_00741_B. AIRS_B.
    InterProiIPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR004733. PurM_cligase.
    IPR016188. PurM_N-like.
    [Graphical view]
    PfamiPF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF55326. SSF55326. 1 hit.
    SSF56042. SSF56042. 1 hit.
    TIGRFAMsiTIGR00878. purM. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B0JTF5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDYKEAGVDV EAGRAFVEKI RQNVESTFRP EVIGGLGGFG GYFQLPSGYR    50
    QPVLVSGTDG VGTKLKIAHS LNCHDTVGID LVAMCVNDVL TSGAEPLFFL 100
    DYLATGKLEA SQLAAVVSGI ARACRDSGCT LLGGETAEMP GFYSAGEYDL 150
    AGFCVGIVEK SQLLDGSKVQ IGDVAIGLAS SGVHSNGFSL VRKIIDTQGL 200
    NWQDCPEILA GSSLGEVLLT PTRLYVKPVL ELLRSGLDIH AMAHITGGGI 250
    PENLPRCLGK GHSVQIYCES WPVLPIFHWL AQMGSVNAEA MFNTFNMGIG 300
    FVIIVPSDLA RSTINQLQSS GINAYQIGEV IAGKGEIVGL D 341
    Length:341
    Mass (Da):36,039
    Last modified:March 18, 2008 - v1
    Checksum:iE11BBE0DCE09F2FF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP009552 Genomic DNA. Translation: BAG04258.1.
    RefSeqiYP_001659450.1. NC_010296.1.

    Genome annotation databases

    EnsemblBacteriaiBAG04258; BAG04258; MAE_44360.
    GeneIDi5865266.
    KEGGimar:MAE_44360.
    PATRICi22633421. VBIMicAer59304_4021.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP009552 Genomic DNA. Translation: BAG04258.1 .
    RefSeqi YP_001659450.1. NC_010296.1.

    3D structure databases

    ProteinModelPortali B0JTF5.
    SMRi B0JTF5. Positions 1-338.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 449447.MAE_44360.

    Proteomic databases

    PaxDbi B0JTF5.
    PRIDEi B0JTF5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAG04258 ; BAG04258 ; MAE_44360 .
    GeneIDi 5865266.
    KEGGi mar:MAE_44360.
    PATRICi 22633421. VBIMicAer59304_4021.

    Phylogenomic databases

    eggNOGi COG0150.
    HOGENOMi HOG000229090.
    KOi K01933.
    OMAi EFEMYRT.
    OrthoDBi EOG61CM1V.

    Enzyme and pathway databases

    UniPathwayi UPA00074 ; UER00129 .
    BioCyci MAER449447:GHO8-4470-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1330.10. 1 hit.
    3.90.650.10. 1 hit.
    HAMAPi MF_00741_B. AIRS_B.
    InterProi IPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR004733. PurM_cligase.
    IPR016188. PurM_N-like.
    [Graphical view ]
    Pfami PF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55326. SSF55326. 1 hit.
    SSF56042. SSF56042. 1 hit.
    TIGRFAMsi TIGR00878. purM. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NIES-843.

    Entry informationi

    Entry nameiPUR5_MICAN
    AccessioniPrimary (citable) accession number: B0JTF5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: March 18, 2008
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3