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B0JT86 (PGK_MICAN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:MAE_43670
OrganismMicrocystis aeruginosa (strain NIES-843) [Complete proteome] [HAMAP]
Taxonomic identifier449447 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesMicrocystis

Protein attributes

Sequence length402 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 402402Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000076593

Regions

Nucleotide binding358 – 3614ATP By similarity
Region24 – 263Substrate binding By similarity
Region64 – 674Substrate binding By similarity

Sites

Binding site411Substrate By similarity
Binding site1231Substrate By similarity
Binding site1561Substrate By similarity
Binding site2071ATP By similarity
Binding site2981ATP; via carbonyl oxygen By similarity
Binding site3291ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
B0JT86 [UniParc].

Last modified March 18, 2008. Version 1.
Checksum: C688F8E84E53E4A0

FASTA40242,640
        10         20         30         40         50         60 
MPKKTVANLT EADLAGKRVL VRVDFNVPMD KATGAISDDT RIRAALPTIE DLIKKGAKVI 

        70         80         90        100        110        120 
LCSHMGRPDG QVKENLRLTP VAKRLSELLG QEVIMCPDCI GEGVTAAISQ MSNGQVALLE 

       130        140        150        160        170        180 
NLRFHGEEEA NDPDFAKKLA ANADLYVNDA FGTAHRAHAS TEGVTHYLSP SVAGYLIEKE 

       190        200        210        220        230        240 
LNYLQAAIET PQRPLAAIIG GSKVSSKIGV IETLLEKCDK LLIGGGMIFT FYKARGLSVG 

       250        260        270        280        290        300 
KSLVEEDKLE LAKSLEAKAK EKGVEFLLPT DVVLADKFDK DAESQIVKVE NIPDGWMGLD 

       310        320        330        340        350        360 
IGPESVKVFQ EALSNCKSVL WNGPMGVFEF DKFAAGTDAI AHTLADLTAT GTTTIIGGGD 

       370        380        390        400 
SVAAVEKVGV AEKMSHISTG GGASLELLEG KVLPGIAALD EA 

« Hide

References

[1]"Complete genomic structure of the bloom-forming toxic cyanobacterium Microcystis aeruginosa NIES-843."
Kaneko T., Nakajima N., Okamoto S., Suzuki I., Tanabe Y., Tamaoki M., Nakamura Y., Kasai F., Watanabe A., Kawashima K., Kishida Y., Ono A., Shimizu Y., Takahashi C., Minami C., Fujishiro T., Kohara M., Katoh M. expand/collapse author list , Nakazaki N., Nakayama S., Yamada M., Tabata S., Watanabe M.M.
DNA Res. 14:247-256(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NIES-843.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP009552 Genomic DNA. Translation: BAG04189.1.
RefSeqYP_001659381.1. NC_010296.1.

3D structure databases

ProteinModelPortalB0JT86.
SMRB0JT86. Positions 1-401.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING449447.MAE_43670.

Proteomic databases

PaxDbB0JT86.
PRIDEB0JT86.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAG04189; BAG04189; MAE_43670.
GeneID5865197.
KEGGmar:MAE_43670.
PATRIC22633307. VBIMicAer59304_3964.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OMAGLDCGEK.
OrthoDBEOG64N9Z0.
ProtClustDBPRK00073.

Enzyme and pathway databases

BioCycMAER449447:GHO8-4401-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_MICAN
AccessionPrimary (citable) accession number: B0JT86
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 18, 2008
Last modified: February 19, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways