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B0JQ22 (B0JQ22_MICAN) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase 1 HAMAP MF_01840
Short name=Mg-protoporphyrin IX monomethyl ester oxidative cyclase 1 HAMAP MF_01840
EC=1.14.13.81 HAMAP MF_01840
Gene names
Name:acsF1 HAMAP MF_01840
Ordered Locus Names:MAE_39240
OrganismMicrocystis aeruginosa (strain NIES-843) [Complete proteome] [HAMAP]
Taxonomic identifier449447 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Microcystis

Protein attributes

Sequence length358 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) By similarity. HAMAP MF_01840

Catalytic activity

131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O. HAMAP MF_01840

131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = divinylprotochlorophyllide + NADP+ + 2 H2O. HAMAP MF_01840

Magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O. HAMAP MF_01840

Cofactor

Iron By similarity. HAMAP MF_01840

Pathway

Porphyrin biosynthesis; chlorophyll biosynthesis (light-independent). HAMAP MF_01840

Sequence similarities

Belongs to the AcsF family. HAMAP MF_01840

Sequences

Sequence LengthMass (Da)Tools
B0JQ22 [UniParc].

Last modified March 18, 2008. Version 1.
Checksum: 04D3CDDBC0117B23

FASTA35842,467
        10         20         30         40         50         60 
MVSTIQKPEF EEIRPGIKVP AKETILTPRF YTTDFEAMAE MSIAANEEEL KAILEEFRTD 

        70         80         90        100        110        120 
YNRHHFVRNQ EFDRSWEHID GETRRLFVEF LERSCTAEFS GFLLYKELGR RLKNRNPVLA 

       130        140        150        160        170        180 
ECFNLMSRDE ARHAGFLNKA LSDFNLSLDL GFLTKSRNYT FFKPKFIFYA TYLSEKIGYW 

       190        200        210        220        230        240 
RYITIYRHLE QHPEDRVYPI FNFFENWCQD ENRHGDFFDA IMRAQPDILN DWRARLWCRF 

       250        260        270        280        290        300 
FLLSVFATMY LNDTQRSGFY AILGLDAREY DKYVIEKTNE TAGRVFPIVL DVDSPEFYDR 

       310        320        330        340        350 
LEICVGNNEG LRAIDSENSP APVKFLKKLP IFASNAWQFL KLYLMKPIRV DKLAGSVR

« Hide

References

[1]"Complete genomic structure of the bloom-forming toxic cyanobacterium Microcystis aeruginosa NIES-843."
Kaneko T., Nakajima N., Okamoto S., Suzuki I., Tanabe Y., Tamaoki M., Nakamura Y., Kasai F., Watanabe A., Kawashima K., Kishida Y., Ono A., Shimizu Y., Takahashi C., Minami C., Fujishiro T., Kohara M., Katoh M. expand/collapse author list , Nakazaki N., Nakayama S., Yamada M., Tabata S., Watanabe M.M.
DNA Res. 14:247-256(2007) [PubMed: 18192279] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009552 Genomic DNA. Translation: BAG03746.1.
RefSeqYP_001658938.1. NC_010296.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB0JQ22.

Proteomic databases

PRIDEB0JQ22.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5864752.
GenomeReviewsGene locus MAE_39240 in contig AP009552_GR.
KEGGmar:MAE_39240.
PATRIC22632479. VBIMicAer59304_3552.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG284843.
OMAHGDFFDA.
PhylomeDBB0JQ22.
ProtClustDBPRK13654.

Family and domain databases

HAMAPMF_01840. AcsF.
[Tree]
InterProIPR008434. AcsF.
IPR012347. Ferritin-rel.
IPR009078. Ferritin/RR-like.
IPR003251. Rubrerythrin.
[Graphical view]
Gene3DG3DSA:1.20.1260.10. Ferritin_rel. 1 hit.
KOK04035.
PfamPF02915. Rubrerythrin. 1 hit.
[Graphical view]
SUPFAMSSF47240. Ferritin/RR_like. 1 hit.
TIGRFAMsTIGR02029. AcsF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB0JQ22_MICAN
AccessionPrimary (citable) accession number: B0JQ22
Entry history
Integrated into UniProtKB/TrEMBL: March 18, 2008
Last sequence update: March 18, 2008
Last modified: December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info