B0JPZ9 (B0JPZ9_MICAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid A disaccharide synthase EMBL BAG03723.1

Gene names

Ordered Locus Names:

MAE_39010

Organism

Microcystis aeruginosa (strain NIES-843) [Complete proteome] [HAMAP]

Taxonomic identifier

449447 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Microcystis

Protein attributes

Sequence length	409 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0JPZ9 [UniParc]. Last modified March 18, 2008. Version 1. Checksum: CE96E7D940DC352F	FASTA	409	45,791
	10 20 30 40 50 60 MRIFISTGEV SGDLQAAMLI ESLFKLAKTQ AIELEIFALG GDRMELAGAK MLGKTTRLAA 70 80 90 100 110 120 MGLIESIPFI WPTLQLQKRA KEFFKDHPPD LIILIDYVGA NVAIGQSAKK IIPQVPIIYY 130 140 150 160 170 180 IAPQVWIWSE ENIPSAKLRA TAEKLFNTEK LIAVTDKLLA IFPAEARFFE TKGLPVTWVG 190 200 210 220 230 240 HPLVDRMANA PNRQEMRQKW AIKPEETVIA LLPASRQQEF KYLVPTVCAA AKKLQEKIPD 250 260 270 280 290 300 IKFLIPVPLA LYEPKMRELV KEYGLNAVIM ERDQTLEAIA AADLAVAKSG TVNLEIALLN 310 320 330 340 350 360 VPQVVVYRLS VVTAWIARNI MKLSVPFVSP VNLVLMREIV PELLQEEANP ERIMQECLDL 370 380 390 400 LLNQQRRQKM LNEYAETKAG LGTVGSCERV AQEVLNFTDQ VPKNQKKAG

References

[1]

"Complete genomic structure of the bloom-forming toxic cyanobacterium Microcystis aeruginosa NIES-843." Kaneko T., Nakajima N., Okamoto S., Suzuki I., Tanabe Y., Tamaoki M., Nakamura Y., Kasai F., Watanabe A., Kawashima K., Kishida Y., Ono A., Shimizu Y., Takahashi C., Minami C., Fujishiro T., Kohara M., Katoh M. , Nakazaki N., Nakayama S., Yamada M., Tabata S., Watanabe M.M. DNA Res. 14:247-256(2007) [PubMed: 18192279] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009552 Genomic DNA. Translation: BAG03723.1.
RefSeq	YP_001658915.1. NC_010296.1.
3D structure databases
ProteinModelPortal	B0JPZ9.
ModBase	Search...
Protein-protein interaction databases
STRING	B0JPZ9.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5864725.
GenomeReviews	Gene locus MAE_39010 in contig AP009552_GR.
KEGG	mar:MAE_39010.
PATRIC	22632433. VBIMicAer59304_3533.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG584837.
OMA	IGLANIM.
PhylomeDB	B0JPZ9.
ProtClustDB	PRK00025.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B0JPZ9_MICAN

Accession

Primary (citable) accession number: B0JPZ9

Entry history

Integrated into UniProtKB/TrEMBL:	March 18, 2008
Last sequence update:	March 18, 2008
Last modified:	December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)