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B0JPM4 (GLSA_MICAN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:MAE_37760
OrganismMicrocystis aeruginosa (strain NIES-843) [Complete proteome] [HAMAP]
Taxonomic identifier449447 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesMicrocystis

Protein attributes

Sequence length338 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 338338Glutaminase HAMAP-Rule MF_00313
PRO_0000336031

Sites

Binding site801Substrate By similarity
Binding site1301Substrate By similarity
Binding site1741Substrate By similarity
Binding site1811Substrate By similarity
Binding site2051Substrate By similarity
Binding site2571Substrate By similarity
Binding site2751Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
B0JPM4 [UniParc].

Last modified March 18, 2008. Version 1.
Checksum: 4D83355EA9F0A2D5

FASTA33837,192
        10         20         30         40         50         60 
MASPKDFISP VNSGQKLVYP FRNYLNYLHD KYSDLQTGKI ADYIPELALA APQWFGISVI 

        70         80         90        100        110        120 
TTDGQIFEVG DCQQTFTVQS ISKAFVFGLA LEDHGREYVN SKVGVEPTGE AFNSIILDEK 

       130        140        150        160        170        180 
TNRPYNPMVN AGAIATTDLI TGQNATERLK RILEMFKRYT GRDHEINVPV FLSEKSTGNR 

       190        200        210        220        230        240 
NRAMAYLMLN FGMVSDKIEE TLDLYCQQCA ILVHAHDLAL MAATLANGGV NPITGIRAID 

       250        260        270        280        290        300 
EHYVQDVISV MLTCGMYDAS GEWAYRVGLP AKSGVGGGIT AVVPHQLGIG TFSPLLDEKG 

       310        320        330 
NSIRGVKICQ NISEDFGLHL FNVAKPERDL KTWLEGNS 

« Hide

References

[1]"Complete genomic structure of the bloom-forming toxic cyanobacterium Microcystis aeruginosa NIES-843."
Kaneko T., Nakajima N., Okamoto S., Suzuki I., Tanabe Y., Tamaoki M., Nakamura Y., Kasai F., Watanabe A., Kawashima K., Kishida Y., Ono A., Shimizu Y., Takahashi C., Minami C., Fujishiro T., Kohara M., Katoh M. expand/collapse author list , Nakazaki N., Nakayama S., Yamada M., Tabata S., Watanabe M.M.
DNA Res. 14:247-256(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NIES-843.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP009552 Genomic DNA. Translation: BAG03598.1.
RefSeqYP_001658790.1. NC_010296.1.

3D structure databases

ProteinModelPortalB0JPM4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING449447.MAE_37760.

Proteomic databases

PaxDbB0JPM4.
PRIDEB0JPM4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAG03598; BAG03598; MAE_37760.
GeneID5864600.
KEGGmar:MAE_37760.
PATRIC22632201. VBIMicAer59304_3417.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMAQRARRIN.
OrthoDBEOG6N94BK.

Enzyme and pathway databases

BioCycMAER449447:GHO8-3804-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_MICAN
AccessionPrimary (citable) accession number: B0JPM4
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 18, 2008
Last modified: May 14, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families