B0JPG5 (PCYA_MICAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phycocyanobilin:ferredoxin oxidoreductase
EC=1.3.7.5

Gene names

Name:	pcyA
Ordered Locus Names:	MAE_06540

Organism

Microcystis aeruginosa (strain NIES-843) [Complete proteome] [HAMAP]

Taxonomic identifier

449447 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Microcystis

Protein attributes

Sequence length	245 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin By similarity. HAMAP MF_00618
Catalytic activity	(3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IX-alpha + reduced ferredoxin. HAMAP MF_00618
Sequence similarities	Belongs to the HY2 family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phytochromobilin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	cobalt ion binding Inferred from electronic annotation. Source: InterPro phycocyanobilin:ferredoxin oxidoreductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 245	245	Phycocyanobilin:ferredoxin oxidoreductase HAMAP MF_00618		PRO_1000082583

Sequences

	Sequence		Length	Mass (Da)
	B0JPG5 [UniParc]. Last modified March 18, 2008. Version 1. Checksum: 35039FE4DB069EB6	FASTA	245	27,685
	10 20 30 40 50 60 MIAVTTPEIL PLLHPLIGQL ATAILSHWEN YLDLSPFELP EGLGYVEGRL EGEKLIIENR 70 80 90 100 110 120 CYQTPQFRKM HLELAKLGNG LDILHCVMFP RPEYPLPMFG CDIVSGKAGI SAAIVDLSPT 130 140 150 160 170 180 SGDKTLPSAY NQALAALPGA DFAQARDLPP WGHIFSQYCL FIRPETAAEE RQFLQRVTDF 190 200 210 220 230 240 LTIHCKCARE SQPLSGEEAR IYLQGQRDYC SQQQKNDKTR RVLEKAFGWE WAERYMTGVL FDLPD

References

[1]

"Complete genomic structure of the bloom-forming toxic cyanobacterium Microcystis aeruginosa NIES-843." Kaneko T., Nakajima N., Okamoto S., Suzuki I., Tanabe Y., Tamaoki M., Nakamura Y., Kasai F., Watanabe A., Kawashima K., Kishida Y., Ono A., Shimizu Y., Takahashi C., Minami C., Fujishiro T., Kohara M., Katoh M. , Nakazaki N., Nakayama S., Yamada M., Tabata S., Watanabe M.M. DNA Res. 14:247-256(2007) [PubMed: 18192279] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NIES-843.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009552 Genomic DNA. Translation: BAG00476.1.
RefSeq	YP_001655668.1. NC_010296.1.
3D structure databases
ProteinModelPortal	B0JPG5.
SMR	B0JPG5. Positions 5-245.
ModBase	Search...
Protein-protein interaction databases
STRING	B0JPG5.
Proteomic databases
PRIDE	B0JPG5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5861451.
GenomeReviews	Gene locus MAE_06540 in contig AP009552_GR.
KEGG	mar:MAE_06540.
PATRIC	22626515. VBIMicAer59304_0598.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG561233.
OMA	NDKTRRV.
PhylomeDB	B0JPG5.
ProtClustDB	PRK02816.
Enzyme and pathway databases
BioCyc	MAER449447:MAE_06540-MONOMER.
Family and domain databases
HAMAP	MF_00618. Ferredoxin_bilin_red. [Tree]
InterPro	IPR009249. Ferredoxin-dep_bilin_Rdtase. IPR022870. Ferredoxin_bilin_OxRdtase. [Graphical view]
KO	K05371.
Pfam	PF05996. Fe_bilin_red. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PCYA_MICAN

Accession

Primary (citable) accession number: B0JPG5

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	March 18, 2008
Last modified:	January 25, 2012
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program