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B0JLI8 (SYR_MICAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:MAE_31900
OrganismMicrocystis aeruginosa (strain NIES-843) [Complete proteome] [HAMAP]
Taxonomic identifier449447 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesMicrocystis

Protein attributes

Sequence length585 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 585585Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000076221

Regions

Motif126 – 13611"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
B0JLI8 [UniParc].

Last modified March 18, 2008. Version 1.
Checksum: D38D6794AE298A9C

FASTA58565,637
        10         20         30         40         50         60 
MTAIIQQIKE RFSQSLVKSF GENFADTDPL IVAASNPRFG DYQCNISLSL AKELKQKPRE 

        70         80         90        100        110        120 
VAATLLKNLE IDDLCQTPEI AGPGFINLTL KPSYLETQLK DLITDNRLGV ATANPSQKII 

       130        140        150        160        170        180 
VDFSSPNIAK EMHVGHLRST IIGDCIARIL EFRHHQVIRL NHVGDWGTQF GMLITYLQEA 

       190        200        210        220        230        240 
YPSALTQADA LDLGDLVSFY KKAKIRFDED ENFKETARQA VVKLQSGDPQ SRQAWQLLCQ 

       250        260        270        280        290        300 
QSRREFQKIY DILDIKLTER GESFYNPYLE AVIRELDQQG LLTEDNGALC VFLDGFTNKE 

       310        320        330        340        350        360 
GEPLPLIVKK SDGGYNYATT DLAAICYRVR EDKAERIIYV TDAGQANHFA QVFQVAKKAG 

       370        380        390        400        410        420 
FLPDNVAVVH VAFGLVLGED GKKLKTRSGE TVKLQELLDQ AIACSLADLE KRLASEEREE 

       430        440        450        460        470        480 
TGDFIAKTAE TVGLSAVKYA DLSQNRHSNY VFSYDKMLNL QGNTAPYMLY AYARVQSISR 

       490        500        510        520        530        540 
EGGINFQDLS ANSSLILKDE SELILAKQLL QLPEVISAVE EDLLPNRLCD YLYELSKKYN 

       550        560        570        580 
RFYENCPVLK AAEPIKTSRL FLCDLTARTL KLGLSLLGIP VLERM 

« Hide

References

[1]"Complete genomic structure of the bloom-forming toxic cyanobacterium Microcystis aeruginosa NIES-843."
Kaneko T., Nakajima N., Okamoto S., Suzuki I., Tanabe Y., Tamaoki M., Nakamura Y., Kasai F., Watanabe A., Kawashima K., Kishida Y., Ono A., Shimizu Y., Takahashi C., Minami C., Fujishiro T., Kohara M., Katoh M. expand/collapse author list , Nakazaki N., Nakayama S., Yamada M., Tabata S., Watanabe M.M.
DNA Res. 14:247-256(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NIES-843.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP009552 Genomic DNA. Translation: BAG03012.1.
RefSeqYP_001658204.1. NC_010296.1.

3D structure databases

ProteinModelPortalB0JLI8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING449447.MAE_31900.

Proteomic databases

PaxDbB0JLI8.
PRIDEB0JLI8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAG03012; BAG03012; MAE_31900.
GeneID5864007.
KEGGmar:MAE_31900.
PATRIC22631137. VBIMicAer59304_2891.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycMAER449447:GHO8-3211-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_MICAN
AccessionPrimary (citable) accession number: B0JLI8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 18, 2008
Last modified: April 16, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries