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Protein

Phosphoribosylaminoimidazole-succinocarboxamide synthase

Gene

purC

Organism
Microcystis aeruginosa (strain NIES-843)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate.UniRule annotationSAAS annotation

Pathwayi

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationSAAS annotation

Keywords - Biological processi

Purine biosynthesisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciMAER449447:GHO8-3159-MONOMER.
UniPathwayiUPA00074; UER00131.
UPA00074; UER00131.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylaminoimidazole-succinocarboxamide synthaseUniRule annotationSAAS annotation (EC:6.3.2.6UniRule annotationSAAS annotation)
Alternative name(s):
SAICAR synthetaseUniRule annotation
Gene namesi
Name:purCUniRule annotationImported
Ordered Locus Names:MAE_31380Imported
OrganismiMicrocystis aeruginosa (strain NIES-843)Imported
Taxonomic identifieri449447 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesMicrocystis
ProteomesiUP000001510 Componenti: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiB0JLD6.

Interactioni

Protein-protein interaction databases

STRINGi449447.MAE_31380.

Structurei

3D structure databases

ProteinModelPortaliB0JLD6.
SMRiB0JLD6. Positions 2-236.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SAICAR synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0152.
HOGENOMiHOG000082629.
KOiK01923.
OMAiFNAQKRG.
OrthoDBiEOG62C9HN.

Family and domain databases

Gene3Di3.30.470.20. 1 hit.
HAMAPiMF_00137. SAICAR_synth.
InterProiIPR013816. ATP_grasp_subdomain_2.
IPR028923. SAICAR_synt/ADE2_N.
IPR001636. SAICAR_synth.
IPR018236. SAICAR_synthetase_CS.
[Graphical view]
PfamiPF01259. SAICAR_synt. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00081. purC. 1 hit.
PROSITEiPS01057. SAICAR_SYNTHETASE_1. 1 hit.
PS01058. SAICAR_SYNTHETASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0JLD6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKLYEGKAK ILYQTDDPDI LLTYYKDDAT AFNAQKRGQI VGKGEINCTV
60 70 80 90 100
STALFQWLES LGIPTHYIDR PSSREMRVKA IKIIPLEVVV RNIAAGSLCK
110 120 130 140 150
QTGLKEGKVL PFPLVEFYLK DDALGDPLLT PDRIKVIDIA SEEQVNQLRD
160 170 180 190 200
LALQINQYLQ EFFDKCQIIL VDFKLEFGVD KTGKIYLGDE ISPDTCRLWD
210 220 230 240
KTQEDAQARI LDKDRFRRDL GDVETAYQQV QARVLQQIES L
Length:241
Mass (Da):27,562
Last modified:March 18, 2008 - v1
Checksum:iBA9DA872277297EB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009552 Genomic DNA. Translation: BAG02960.1.
RefSeqiWP_002784616.1. NC_010296.1.
YP_001658152.1. NC_010296.1.

Genome annotation databases

EnsemblBacteriaiBAG02960; BAG02960; MAE_31380.
KEGGimar:MAE_31380.
PATRICi22631037. VBIMicAer59304_2841.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009552 Genomic DNA. Translation: BAG02960.1.
RefSeqiWP_002784616.1. NC_010296.1.
YP_001658152.1. NC_010296.1.

3D structure databases

ProteinModelPortaliB0JLD6.
SMRiB0JLD6. Positions 2-236.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi449447.MAE_31380.

Proteomic databases

PRIDEiB0JLD6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAG02960; BAG02960; MAE_31380.
KEGGimar:MAE_31380.
PATRICi22631037. VBIMicAer59304_2841.

Phylogenomic databases

eggNOGiCOG0152.
HOGENOMiHOG000082629.
KOiK01923.
OMAiFNAQKRG.
OrthoDBiEOG62C9HN.

Enzyme and pathway databases

UniPathwayiUPA00074; UER00131.
UPA00074; UER00131.
BioCyciMAER449447:GHO8-3159-MONOMER.

Family and domain databases

Gene3Di3.30.470.20. 1 hit.
HAMAPiMF_00137. SAICAR_synth.
InterProiIPR013816. ATP_grasp_subdomain_2.
IPR028923. SAICAR_synt/ADE2_N.
IPR001636. SAICAR_synth.
IPR018236. SAICAR_synthetase_CS.
[Graphical view]
PfamiPF01259. SAICAR_synt. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00081. purC. 1 hit.
PROSITEiPS01057. SAICAR_SYNTHETASE_1. 1 hit.
PS01058. SAICAR_SYNTHETASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NIES-843Imported.

Entry informationi

Entry nameiB0JLD6_MICAN
AccessioniPrimary (citable) accession number: B0JLD6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 18, 2008
Last sequence update: March 18, 2008
Last modified: May 27, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.