ID   CYSC_MICAN              Reviewed;         181 AA.
AC   B0JL16;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   18-MAR-2008, sequence version 1.
DT   16-JUN-2009, entry version 8.
DE   RecName: Full=Adenylyl-sulfate kinase;
DE            EC=2.7.1.25;
DE   AltName: Full=APS kinase;
DE   AltName: Full=Adenosine-5'-phosphosulfate kinase;
DE   AltName: Full=ATP adenosine-5'-phosphosulfate 3'-phosphotransferase;
GN   Name=cysC; OrderedLocusNames=MAE_31330;
OS   Microcystis aeruginosa (strain NIES-843).
OC   Bacteria; Cyanobacteria; Chroococcales; Microcystis.
OX   NCBI_TaxID=449447;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=18192279; DOI=10.1093/dnares/dsm026;
RA   Kaneko T., Nakajima N., Okamoto S., Suzuki I., Tanabe Y., Tamaoki M.,
RA   Nakamura Y., Kasai F., Watanabe A., Kawashima K., Kishida Y., Ono A.,
RA   Shimizu Y., Takahashi C., Minami C., Fujishiro T., Kohara M.,
RA   Katoh M., Nakazaki N., Nakayama S., Yamada M., Tabata S.,
RA   Watanabe M.M.;
RT   "Complete genomic structure of the bloom-forming toxic cyanobacterium
RT   Microcystis aeruginosa NIES-843.";
RL   DNA Res. 14:247-256(2007).
CC   -!- FUNCTION: Catalyzes the synthesis of activated sulfate (By
CC       similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + adenylyl sulfate = ADP + 3'-
CC       phosphoadenylyl sulfate.
CC   -!- PATHWAY: Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite
CC       from sulfate: step 2/3.
CC   -!- SIMILARITY: Belongs to the APS kinase family.
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DR   EMBL; AP009552; BAG02955.1; -; Genomic_DNA.
DR   RefSeq; YP_001658147.1; -.
DR   GeneID; 5863950; -.
DR   GenomeReviews; AP009552_GR; MAE_31330.
DR   KEGG; mar:MAE_31330; -.
DR   OMA; B0JL16; IITITAF.
DR   GO; GO:0004020; F:adenylylsulfate kinase activity; IEA:HAMAP.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0000103; P:sulfate assimilation; IEA:HAMAP.
DR   HAMAP; MF_00065; -; 1.
DR   InterPro; IPR002891; APS_kinase_C.
DR   Pfam; PF01583; APS_kinase; 1.
DR   ProDom; PD002350; APS_kinase; 1.
DR   TIGRFAMs; TIGR00455; apsK; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Kinase; Nucleotide-binding;
KW   Phosphoprotein; Transferase.
FT   CHAIN         1    181       Adenylyl-sulfate kinase.
FT                                /FTId=PRO_1000075086.
FT   NP_BIND      12     19       ATP (By similarity).
FT   ACT_SITE     86     86       Phosphoserine intermediate (By
FT                                similarity).
SQ   SEQUENCE   181 AA;  20110 MW;  F577C482D0D63DC2 CRC64;
     MKQRGVTVWL TGLSGAGKST ITEALQAKLI AEGYSIEVLD GDIVRTNLTK GLGFSKEDRD
     ENIRRIGFVS NLLTRHGVIV LVSAISPYRE IREEVRGKIG NFVEVFVNAP LSVCEDRDVK
     GLYKRARAGE IKSFTGIDDP YEPPFNPEVE CRTDLETLEE SVAKVWNKLT ELGYIHQAVA
     V
//