B0JGW5 (MURI_MICAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamate racemase
EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	MAE_55590

Organism

Microcystis aeruginosa (strain NIES-843) [Complete proteome] [HAMAP]

Taxonomic identifier

449447 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Microcystis

Protein attributes

Sequence length	283 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 283	283	Glutamate racemase HAMAP MF_00258		PRO_1000119189

Sequences

	Sequence		Length	Mass (Da)
	B0JGW5 [UniParc]. Last modified March 18, 2008. Version 1. Checksum: 3706F15772F43769	FASTA	283	31,602
	10 20 30 40 50 60 MRESQLSPIG VFDSGVGGLT VLRELYRQLP QESILYFADT ARLPYGTRSK GEIIEFVLEI 70 80 90 100 110 120 LTWMSERRVK MVIMACNTSS ALALEEVQAE FKDLPILGVI LPGAKTAVQK GKRIGVISTP 130 140 150 160 170 180 ATAKSNAYKQ AIQEIDPTAQ VWQIPCPEFV PLIEANRIFD PYTTQVAREY LQPLLAENID 190 200 210 220 230 240 TLVYGCTHYR HLSPVLRRLL PSSVRLVDPA ASVVRAAEKE LELLGLKNPE TPLPTNFAVS 250 260 270 280 GDPDTFARLS RQWLGFSPRV EKVYLQCRVK TLGFTDGMKQ RPV

References

[1]

"Complete genomic structure of the bloom-forming toxic cyanobacterium Microcystis aeruginosa NIES-843." Kaneko T., Nakajima N., Okamoto S., Suzuki I., Tanabe Y., Tamaoki M., Nakamura Y., Kasai F., Watanabe A., Kawashima K., Kishida Y., Ono A., Shimizu Y., Takahashi C., Minami C., Fujishiro T., Kohara M., Katoh M. , Nakazaki N., Nakayama S., Yamada M., Tabata S., Watanabe M.M. DNA Res. 14:247-256(2007) [PubMed: 18192279] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NIES-843.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009552 Genomic DNA. Translation: BAG05381.1.
RefSeq	YP_001660573.1. NC_010296.1.
3D structure databases
ProteinModelPortal	B0JGW5.
ModBase	Search...
Protein-protein interaction databases
STRING	B0JGW5.
Proteomic databases
PRIDE	B0JGW5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5866401.
GenomeReviews	Gene locus MAE_55590 in contig AP009552_GR.
KEGG	mar:MAE_55590.
PATRIC	22635545. VBIMicAer59304_5072.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG645102.
OMA	PQEDTIY.
PhylomeDB	B0JGW5.
ProtClustDB	PRK00865.
Enzyme and pathway databases
BioCyc	MAER449447:MAE_55590-MONOMER.
Family and domain databases
HAMAP	MF_00258. Glu_racemase. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
KO	K01776.
PANTHER	PTHR21198. PTHR21198. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
SUPFAM	SSF53681. Asp/Glu_race. 2 hits.
TIGRFAMs	TIGR00067. Glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. 1 hit. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_MICAN

Accession

Primary (citable) accession number: B0JGW5

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	March 18, 2008
Last modified:	January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program