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B0JGA3 (B0JGA3_MICAN) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
GTP cyclohydrolase 1 1 HAMAP MF_00223
EC=3.5.4.16 HAMAP MF_00223
Alternative name(s):
GTP cyclohydrolase I 1 HAMAP MF_00223
Gene names
Name:folE EMBL BAG02108.1
Synonyms:folE1 HAMAP MF_00223
Ordered Locus Names:MAE_22860
OrganismMicrocystis aeruginosa (strain NIES-843) [Complete proteome] [HAMAP]
Taxonomic identifier449447 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Microcystis

Protein attributes

Sequence length218 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate. HAMAP MF_00223 SAAS SAAS001474

Pathway

Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1. HAMAP MF_00223 SAAS SAAS001474

Subunit structure

Homopolymer By similarity. HAMAP MF_00223

Sequence similarities

Belongs to the GTP cyclohydrolase I family. HAMAP MF_00223

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1041Zinc By similarity HAMAP MF_00223
Metal binding1071Zinc By similarity HAMAP MF_00223
Metal binding1751Zinc By similarity HAMAP MF_00223

Sequences

Sequence LengthMass (Da)Tools
B0JGA3 [UniParc].

Last modified March 18, 2008. Version 1.
Checksum: 33A9CAFCCB5A26BA

FASTA21824,327
        10         20         30         40         50         60 
MTLAKSKAIF DNDDYNHFPE VITEPKSPVS EAEMMQAVRT LLLGLGEDPD REGLRDTPKR 

        70         80         90        100        110        120 
VVKALKFLTS GYQQSLDELL NGAVFHENAN EMVLIRDIDI FSSCEHHILP IIGRAHVAYI 

       130        140        150        160        170        180 
PNGKVIGLSK IARICEMYAR RLQVQERLTA QIADALQGLL QPQGVAVVIE ATHMCMVMRG 

       190        200        210 
VEKPGSWTST SAVRGIFADS AKTRQEFMSL IRHSPDFH

« Hide

References

[1]"Complete genomic structure of the bloom-forming toxic cyanobacterium Microcystis aeruginosa NIES-843."
Kaneko T., Nakajima N., Okamoto S., Suzuki I., Tanabe Y., Tamaoki M., Nakamura Y., Kasai F., Watanabe A., Kawashima K., Kishida Y., Ono A., Shimizu Y., Takahashi C., Minami C., Fujishiro T., Kohara M., Katoh M. expand/collapse author list , Nakazaki N., Nakayama S., Yamada M., Tabata S., Watanabe M.M.
DNA Res. 14:247-256(2007) [PubMed: 18192279] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009552 Genomic DNA. Translation: BAG02108.1.
RefSeqYP_001657300.1. NC_010296.1.

3D structure databases

ProteinModelPortalB0JGA3.
SMRB0JGA3. Positions 30-212.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0JGA3.

Proteomic databases

PRIDEB0JGA3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5863096.
GenomeReviewsGene locus MAE_22860 in contig AP009552_GR.
KEGGmar:MAE_22860.
PATRIC22629523. VBIMicAer59304_2090.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG370191.
OMAEPREYLE.
ProtClustDBPRK09347.

Family and domain databases

HAMAPMF_00223. FolE.
[Tree]
InterProIPR001474. GTP_CycHdrlase_I.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
IPR018234. GTP_CycHdrlase_I_CS.
[Graphical view]
KOK01495.
PANTHERPTHR11109. GTP_cyclohydro_I. 1 hit.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
TIGRFAMsTIGR00063. FolE. 1 hit.
PROSITEPS00859. GTP_CYCLOHYDROL_1_1. 1 hit.
PS00860. GTP_CYCLOHYDROL_1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB0JGA3_MICAN
AccessionPrimary (citable) accession number: B0JGA3
Entry history
Integrated into UniProtKB/TrEMBL: March 18, 2008
Last sequence update: March 18, 2008
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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