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B0I1T2

- MYO1G_HUMAN

UniProt

B0I1T2 - MYO1G_HUMAN

Protein

Unconventional myosin-Ig

Gene

MYO1G

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 2 (11 Jan 2011)
      Previous versions | rss
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    Functioni

    Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments By similarity.By similarity
    Precursor of the minor histocompatibility antigen HA-2. More generally, minor histocompatibility antigens (mHags) refer to immunogenic peptide which, when complexed with MHC, can generate an immune response after recognition by specific T-cells. The peptides are derived from polymorphic intracellular proteins, which are cleaved by normal pathways of antigen processing. The binding of these peptides to MHC class I or class II molecules and their expression on the cell surface can stimulate T-cell responses and thereby trigger graft rejection or graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation from HLA-identical sibling donor. GVHD is a frequent complication after bone marrow transplantation (BMT), due to mismatch of minor histocompatibility antigen in HLA-matched sibling marrow transplants. HA-2 is restricted to MHC class I HLA-A*0201.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi102 – 1098ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. motor activity Source: InterPro

    Keywords - Molecular functioni

    Motor protein, Myosin

    Keywords - Ligandi

    Actin-binding, ATP-binding, Calmodulin-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Unconventional myosin-Ig
    Cleaved into the following chain:
    Gene namesi
    Name:MYO1G
    Synonyms:HA2
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 7

    Organism-specific databases

    HGNCiHGNC:13880. MYO1G.

    Subcellular locationi

    Cell membrane 1 Publication; Peripheral membrane protein 1 Publication
    Note: Localization at the membrane is not highly dependent on phosphatidylinositol 4,5-bisphosphate levels. Released from the membrane in the presence of ATP. May be enriched in peripheral processes, such as microvilli or ruffles.

    GO - Cellular componenti

    1. extracellular vesicular exosome Source: UniProt
    2. membrane Source: UniProtKB
    3. myosin complex Source: UniProtKB-KW
    4. plasma membrane Source: MGI

    Keywords - Cellular componenti

    Cell membrane, Membrane

    Pathology & Biotechi

    Mutagenesis

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Mutagenesisi815 – 8151K → A: Reduced membrane association. 1 Publication
    Mutagenesisi826 – 8261R → A: Reduced membrane association. 1 Publication
    Mutagenesisi876 – 8761R → A: No effect on membrane localization. 1 Publication
    Mutagenesisi880 – 8801R → A: No effect on membrane localization. 1 Publication
    Mutagenesisi883 – 8831K → A: No effect on membrane localization; when associated with R-885.
    Mutagenesisi885 – 8851R → A: No effect on membrane localization; when associated with K-883. 1 Publication
    Mutagenesisi898 – 8981K → A: Reduced membrane association. 1 Publication
    Mutagenesisi903 – 9031R → A: No effect on membrane localization; when associated with R-906. 1 Publication
    Mutagenesisi906 – 9061R → A: No effect on membrane localization; when associated with R-903. 1 Publication
    Mutagenesisi909 – 9091R → A: No effect on membrane localization. 1 Publication
    Mutagenesisi934 – 9341R → A: No effect on membrane localization. 1 Publication
    Mutagenesisi945 – 9451R → A: No effect on membrane localization. 1 Publication
    Mutagenesisi947 – 9471R → A: No effect on membrane localization. 1 Publication
    Mutagenesisi953 – 9531R → A: No effect on membrane localization. 1 Publication

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 10181018Unconventional myosin-IgPRO_0000340316Add
    BLAST
    Peptidei41 – 499Minor histocompatibility antigen HA-2PRO_0000340317

    Proteomic databases

    MaxQBiB0I1T2.
    PaxDbiB0I1T2.
    PRIDEiB0I1T2.

    PTM databases

    PhosphoSiteiB0I1T2.

    Expressioni

    Tissue specificityi

    Specifically expressed in hematopoietic cells.2 Publications

    Gene expression databases

    ArrayExpressiB0I1T2.
    BgeeiB0I1T2.
    CleanExiHS_MYO1G.
    GenevestigatoriB0I1T2.

    Organism-specific databases

    HPAiHPA021252.

    Interactioni

    Subunit structurei

    Binds calmodulin through its IQ motifs.By similarity

    Protein-protein interaction databases

    BioGridi122031. 6 interactions.
    IntActiB0I1T2. 4 interactions.
    MINTiMINT-7307233.
    STRINGi9606.ENSP00000258787.

    Structurei

    3D structure databases

    ProteinModelPortaliB0I1T2.
    SMRiB0I1T2. Positions 8-733.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini9 – 707699Myosin motorAdd
    BLAST
    Domaini710 – 73930IQAdd
    BLAST

    Sequence similaritiesi

    Contains 1 IQ domain.Curated
    Contains 1 myosin motor domain.Curated

    Phylogenomic databases

    eggNOGiCOG5022.
    HOGENOMiHOG000260264.
    HOVERGENiHBG062373.
    InParanoidiB0I1T2.
    KOiK10356.
    OMAiEQHGLQG.
    OrthoDBiEOG7V49XQ.
    PhylomeDBiB0I1T2.
    TreeFamiTF312960.

    Family and domain databases

    InterProiIPR000048. IQ_motif_EF-hand-BS.
    IPR001609. Myosin_head_motor_dom.
    IPR010926. Myosin_tail_2.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF00063. Myosin_head. 1 hit.
    PF06017. Myosin_TH1. 1 hit.
    [Graphical view]
    PRINTSiPR00193. MYOSINHEAVY.
    SMARTiSM00015. IQ. 1 hit.
    SM00242. MYSc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS51456. MYOSIN_MOTOR. 1 hit.
    [Graphical view]

    Sequences (4)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 4 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: B0I1T2-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MEDEEGPEYG KPDFVLLDQV TMEDFMRNLQ LRFEKGRIYT YIGEVLVSVN     50
    PYQELPLYGP EAIARYQGRE LYERPPHLYA VANAAYKAMK HRSRDTCIVI 100
    SGESGAGKTE ASKHIMQYIA AVTNPSQRAE VERVKDVLLK STCVLEAFGN 150
    ARTNRNHNSS RFGKYMDINF DFKGDPIGGH IHSYLLEKSR VLKQHVGERN 200
    FHAFYQLLRG SEDKQLHELH LERNPAVYNF THQGAGLNMT VHSALDSDEQ 250
    SHQAVTEAMR VIGFSPEEVE SVHRILAAIL HLGNIEFVET EEGGLQKEGL 300
    AVAEEALVDH VAELTATPRD LVLRSLLART VASGGRELIE KGHTAAEASY 350
    ARDACAKAVY QRLFEWVVNR INSVMEPRGR DPRRDGKDTV IGVLDIYGFE 400
    VFPVNSFEQF CINYCNEKLQ QLFIQLILKQ EQEEYEREGI TWQSVEYFNN 450
    ATIVDLVERP HRGILAVLDE ACSSAGTITD RIFLQTLDMH HRHHLHYTSR 500
    QLCPTDKTME FGRDFRIKHY AGDVTYSVEG FIDKNRDFLF QDFKRLLYNS 550
    TDPTLRAMWP DGQQDITEVT KRPLTAGTLF KNSMVALVEN LASKEPFYVR 600
    CIKPNEDKVA GKLDENHCRH QVAYLGLLEN VRVRRAGFAS RQPYSRFLLR 650
    YKMTCEYTWP NHLLGSDKAA VSALLEQHGL QGDVAFGHSK LFIRSPRTLV 700
    TLEQSRARLI PIIVLLLQKA WRGTLARWRC RRLRAIYTIM RWFRRHKVRA 750
    HLAELQRRFQ AARQPPLYGR DLVWPLPPAV LQPFQDTCHA LFCRWRARQL 800
    VKNIPPSDMP QIKAKVAAMG ALQGLRQDWG CRRAWARDYL SSATDNPTAS 850
    SLFAQRLKTL QDKDGFGAVL FSSHVRKVNR FHKIRNRALL LTDQHLYKLD 900
    PDRQYRVMRA VPLEAVTGLS VTSGGDQLVV LHARGQDDLV VCLHRSRPPL 950
    DNRVGELVGV LAAHCQGEGR TLEVRVSDCI PLSHRGVRRL ISVEPRPEQP 1000
    EPDFRCARGS FTLLWPSR 1018
    Length:1,018
    Mass (Da):116,442
    Last modified:January 11, 2011 - v2
    Checksum:i3EB4ACC3D99A86E9
    GO
    Isoform 2 (identifier: B0I1T2-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         207-230: LLRGSEDKQLHELHLERNPAVYNF → VSPEGKGRWKNGVGKGRAASWTSL
         231-1018: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:230
    Mass (Da):26,151
    Checksum:i7A80030FE7FCCE28
    GO
    Isoform 3 (identifier: B0I1T2-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         526-1018: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:525
    Mass (Da):59,815
    Checksum:i1B25EB82195E4993
    GO
    Isoform 4 (identifier: B0I1T2-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         652-722: KMTCEYTWPN...IVLLLQKAWR → WHLTPITPWA...TGGNMGMRAV
         723-1018: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:722
    Mass (Da):82,279
    Checksum:i6275117D9D1751C1
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti369 – 3691N → K in BAB84961. 1 PublicationCurated
    Sequence conflicti377 – 3771P → L in AAK58092. (PubMed:11544309)Curated
    Sequence conflicti377 – 3771P → L in AAK58093. (PubMed:11544309)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti49 – 491V → M in allele HA-2M; the HA-2V allele constitute the HA-2 epitope while HA-2M is not recognized by HA-2 cytotoxic T lymphocytes. 1 Publication
    Corresponds to variant rs61739531 [ dbSNP | Ensembl ].
    VAR_044013
    Natural varianti489 – 4891M → T.3 Publications
    Corresponds to variant rs3735485 [ dbSNP | Ensembl ].
    VAR_044014
    Natural varianti798 – 7981R → Q.
    Corresponds to variant rs2107737 [ dbSNP | Ensembl ].
    VAR_050212
    Natural varianti861 – 8611Q → R.2 Publications
    Corresponds to variant rs7792760 [ dbSNP | Ensembl ].
    VAR_044015

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei207 – 23024LLRGS…AVYNF → VSPEGKGRWKNGVGKGRAAS WTSL in isoform 2. 1 PublicationVSP_034208Add
    BLAST
    Alternative sequencei231 – 1018788Missing in isoform 2. 1 PublicationVSP_034209Add
    BLAST
    Alternative sequencei526 – 1018493Missing in isoform 3. 1 PublicationVSP_034210Add
    BLAST
    Alternative sequencei652 – 72271KMTCE…QKAWR → WHLTPITPWAIVPVWSPRGR SRGSPNSTSQTSIQAGTSTL LASRHQNIWEDMCVSTCMWG HTGGNMGMRAV in isoform 4. 1 PublicationVSP_034211Add
    BLAST
    Alternative sequencei723 – 1018296Missing in isoform 4. 1 PublicationVSP_034212Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK074050 mRNA. Translation: BAB84876.1. Sequence problems.
    AK074135 mRNA. Translation: BAB84961.1.
    AB290179 mRNA. Translation: BAG06733.1.
    AC004847 Genomic DNA. No translation available.
    AF380932 mRNA. Translation: AAK58092.1.
    AF380933 mRNA. Translation: AAK58093.1.
    BC015693 mRNA. Translation: AAH15693.2.
    CCDSiCCDS34629.1. [B0I1T2-1]
    RefSeqiNP_149043.2. NM_033054.2. [B0I1T2-1]
    UniGeneiHs.37617.

    Genome annotation databases

    EnsembliENST00000258787; ENSP00000258787; ENSG00000136286. [B0I1T2-1]
    GeneIDi64005.
    KEGGihsa:64005.
    UCSCiuc003tmg.2. human. [B0I1T2-1]
    uc003tmi.1. human. [B0I1T2-4]
    uc003tmj.2. human. [B0I1T2-3]

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK074050 mRNA. Translation: BAB84876.1 . Sequence problems.
    AK074135 mRNA. Translation: BAB84961.1 .
    AB290179 mRNA. Translation: BAG06733.1 .
    AC004847 Genomic DNA. No translation available.
    AF380932 mRNA. Translation: AAK58092.1 .
    AF380933 mRNA. Translation: AAK58093.1 .
    BC015693 mRNA. Translation: AAH15693.2 .
    CCDSi CCDS34629.1. [B0I1T2-1 ]
    RefSeqi NP_149043.2. NM_033054.2. [B0I1T2-1 ]
    UniGenei Hs.37617.

    3D structure databases

    ProteinModelPortali B0I1T2.
    SMRi B0I1T2. Positions 8-733.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 122031. 6 interactions.
    IntActi B0I1T2. 4 interactions.
    MINTi MINT-7307233.
    STRINGi 9606.ENSP00000258787.

    PTM databases

    PhosphoSitei B0I1T2.

    Proteomic databases

    MaxQBi B0I1T2.
    PaxDbi B0I1T2.
    PRIDEi B0I1T2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000258787 ; ENSP00000258787 ; ENSG00000136286 . [B0I1T2-1 ]
    GeneIDi 64005.
    KEGGi hsa:64005.
    UCSCi uc003tmg.2. human. [B0I1T2-1 ]
    uc003tmi.1. human. [B0I1T2-4 ]
    uc003tmj.2. human. [B0I1T2-3 ]

    Organism-specific databases

    CTDi 64005.
    GeneCardsi GC07M045003.
    H-InvDB HIX0006659.
    HGNCi HGNC:13880. MYO1G.
    HPAi HPA021252.
    MIMi 613445. gene.
    neXtProti NX_B0I1T2.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG5022.
    HOGENOMi HOG000260264.
    HOVERGENi HBG062373.
    InParanoidi B0I1T2.
    KOi K10356.
    OMAi EQHGLQG.
    OrthoDBi EOG7V49XQ.
    PhylomeDBi B0I1T2.
    TreeFami TF312960.

    Miscellaneous databases

    GenomeRNAii 64005.
    NextBioi 65808.
    PROi B0I1T2.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi B0I1T2.
    Bgeei B0I1T2.
    CleanExi HS_MYO1G.
    Genevestigatori B0I1T2.

    Family and domain databases

    InterProi IPR000048. IQ_motif_EF-hand-BS.
    IPR001609. Myosin_head_motor_dom.
    IPR010926. Myosin_tail_2.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF00063. Myosin_head. 1 hit.
    PF06017. Myosin_TH1. 1 hit.
    [Graphical view ]
    PRINTSi PR00193. MYOSINHEAVY.
    SMARTi SM00015. IQ. 1 hit.
    SM00242. MYSc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS51456. MYOSIN_MOTOR. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The nucleotide sequence of a long cDNA clone isolated from human spleen."
      Jikuya H., Takano J., Nomura N., Kikuno R., Nagase T., Ohara O.
      Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 193-1018 (ISOFORM 3), VARIANT THR-489.
      Tissue: Spleen.
    2. "Multiplex amplification and cloning of 5'-ends of cDNA by ligase-free recombination: preparation of full-length cDNA clones encoding motor proteins."
      Yamakawa H., Kikuno R.F., Nagase T., Ohara O.
      Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANTS THR-489 AND ARG-861.
      Tissue: Spleen.
    3. "The DNA sequence of human chromosome 7."
      Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
      , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
      Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. "The HA-2 minor histocompatibility antigen is derived from a diallelic gene encoding a novel human class I myosin protein."
      Pierce R.A., Field E.D., Mutis T., Golovina T.N., Von Kap-Herr C., Wilke M., Pool J., Shabanowitz J., Pettenati M.J., Eisenlohr L.C., Hunt D.F., Goulmy E., Engelhard V.H.
      J. Immunol. 167:3223-3230(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 33-665 (ISOFORM 4), IDENTIFICATION AS THE MINOR HISTOCOMPATIBILITY ANTIGEN HA-2, VARIANTS HA-2M MET-49 AND THR-489, CHARACTERIZATION OF VARIANT HA-2M MET-49, TISSUE SPECIFICITY.
    5. "Identification of a graft versus host disease-associated human minor histocompatibility antigen."
      den Haan J.M.M., Sherman N.E., Blokland E., Huczko E., Koning F., Drijfhout J.W., Skipper J., Shabanowitz J., Hunt D.F., Engelhard V.H., Goulmy E.
      Science 268:1476-1480(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 41-49 (ISOFORM 1).
    6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 723-1018 (ISOFORM 1), VARIANT ARG-861.
      Tissue: B-cell.
    7. "Myosin 1G is an abundant class I myosin in lymphocytes whose localization at the plasma membrane depends on its ancient divergent pleckstrin homology (PH) domain (Myo1PH)."
      Patino-Lopez G., Aravind L., Dong X., Kruhlak M.J., Ostap E.M., Shaw S.
      J. Biol. Chem. 285:8675-8686(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION, TISSUE SPECIFICITY, MUTAGENESIS OF LYS-815; ARG-826; ARG-876; ARG-880; ARG-885; LYS-898; ARG-903; ARG-906; ARG-909; ARG-934; ARG-945; ARG-947 AND ARG-953.

    Entry informationi

    Entry nameiMYO1G_HUMAN
    AccessioniPrimary (citable) accession number: B0I1T2
    Secondary accession number(s): Q8TEI9
    , Q8TES2, Q96BE2, Q96RI5, Q96RI6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 10, 2008
    Last sequence update: January 11, 2011
    Last modified: October 1, 2014
    This is version 58 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Human chromosome 7
      Human chromosome 7: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3