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Protein

Uroplakin-3b-like protein

Gene

UPK3BL

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uroplakin-3b-like protein
Gene namesi
Name:UPK3BL
Synonyms:UPLP
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 7

Organism-specific databases

HGNCiHGNC:37278. UPK3BL.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini34 – 204171ExtracellularSequence AnalysisAdd
BLAST
Transmembranei205 – 22521HelicalSequence AnalysisAdd
BLAST
Topological domaini226 – 26338CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA165618441.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3333Sequence AnalysisAdd
BLAST
Chaini34 – 263230Uroplakin-3b-like proteinPRO_0000375087Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi51 – 511N-linked (GlcNAc...)Sequence Analysis
Glycosylationi76 – 761N-linked (GlcNAc...)Sequence Analysis
Glycosylationi91 – 911N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiB0FP48.
PRIDEiB0FP48.

PTM databases

PhosphoSiteiB0FP48.

Expressioni

Gene expression databases

BgeeiB0FP48.
ExpressionAtlasiB0FP48. baseline.
GenevestigatoriB0FP48.

Organism-specific databases

HPAiHPA011403.

Interactioni

Protein-protein interaction databases

BioGridi756078. 14 interactions.

Structurei

3D structure databases

ProteinModelPortaliB0FP48.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uroplakin-3 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG26593.
HOGENOMiHOG000293265.
InParanoidiB0FP48.
OMAiETEWSSE.
PhylomeDBiB0FP48.
TreeFamiTF336628.

Family and domain databases

InterProiIPR024831. Uroplakin-3.
IPR024827. Uroplakin-3b-like.
[Graphical view]
PANTHERiPTHR15446. PTHR15446. 1 hit.
PTHR15446:SF2. PTHR15446:SF2. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

B0FP48-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDNSWRLGPA IGLSAGQSQL LVSLLLLLTR VQPGTDVAAP EHISYVPQLS
60 70 80 90 100
NDTLAGRLTL STFTLEQPLG QFSSHNISDL DTIWLVVALS NATQSFTAPR
110 120 130 140 150
TNQDIPAPAN FSQRGYYLTL RANRVLYQTR GQLHVLRVGN DTHCQPTKIG
160 170 180 190 200
CNHPLPGPGP YRVKFLVMND EGPVAETKWS SDTRLQQAQA LRAVPGPQSP
210 220 230 240 250
GTVVIIAILS ILLAVLLTVL LAVLIYTCFN SCRSTSLSGP EEAGSVRRYT
260
THLAFSTPAE GAS
Length:263
Mass (Da):28,385
Last modified:February 26, 2008 - v1
Checksum:iCBA7419B03F7A57E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU341824 mRNA. Translation: ABY56115.1.
CCDSiCCDS47675.1.
RefSeqiNP_001107875.1. NM_001114403.2.
XP_006716284.1. XM_006716221.1.
UniGeneiHs.610255.

Genome annotation databases

EnsembliENST00000340457; ENSP00000342938; ENSG00000267368.
GeneIDi100134938.
102724187.
KEGGihsa:100134938.
hsa:102724187.
UCSCiuc003uzw.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU341824 mRNA. Translation: ABY56115.1.
CCDSiCCDS47675.1.
RefSeqiNP_001107875.1. NM_001114403.2.
XP_006716284.1. XM_006716221.1.
UniGeneiHs.610255.

3D structure databases

ProteinModelPortaliB0FP48.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi756078. 14 interactions.

PTM databases

PhosphoSiteiB0FP48.

Proteomic databases

PaxDbiB0FP48.
PRIDEiB0FP48.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000340457; ENSP00000342938; ENSG00000267368.
GeneIDi100134938.
102724187.
KEGGihsa:100134938.
hsa:102724187.
UCSCiuc003uzw.2. human.

Organism-specific databases

CTDi100134938.
GeneCardsiGC07M102283.
HGNCiHGNC:37278. UPK3BL.
HPAiHPA011403.
neXtProtiNX_B0FP48.
PharmGKBiPA165618441.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG26593.
HOGENOMiHOG000293265.
InParanoidiB0FP48.
OMAiETEWSSE.
PhylomeDBiB0FP48.
TreeFamiTF336628.

Miscellaneous databases

NextBioi20774768.
PROiB0FP48.

Gene expression databases

BgeeiB0FP48.
ExpressionAtlasiB0FP48. baseline.
GenevestigatoriB0FP48.

Family and domain databases

InterProiIPR024831. Uroplakin-3.
IPR024827. Uroplakin-3b-like.
[Graphical view]
PANTHERiPTHR15446. PTHR15446. 1 hit.
PTHR15446:SF2. PTHR15446:SF2. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Human uroplakin-like protein."
    Wistow G.
    Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Eye.

Entry informationi

Entry nameiUPK3L_HUMAN
AccessioniPrimary (citable) accession number: B0FP48
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 26, 2009
Last sequence update: February 26, 2008
Last modified: January 7, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.