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Protein

Uroplakin-3b-like protein 1

Gene

UPK3BL1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uroplakin-3b-like protein 1Imported
Gene namesi
Name:UPK3BL1Imported
Synonyms:UPLP
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

HGNCiHGNC:37278. UPK3BL1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini34 – 204ExtracellularSequence analysisAdd BLAST171
Transmembranei205 – 225HelicalSequence analysisAdd BLAST21
Topological domaini226 – 263CytoplasmicSequence analysisAdd BLAST38

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000267368.
PharmGKBiPA165618441.

Polymorphism and mutation databases

BioMutaiUPK3BL.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 33Sequence analysisAdd BLAST33
ChainiPRO_000037508734 – 263Uroplakin-3b-like protein 1Add BLAST230

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi51N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi76N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi91N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiB0FP48.
PRIDEiB0FP48.

PTM databases

iPTMnetiB0FP48.
PhosphoSitePlusiB0FP48.

Expressioni

Gene expression databases

BgeeiENSG00000267368.
ExpressionAtlasiB0FP48. baseline and differential.

Organism-specific databases

HPAiHPA011403.

Interactioni

Protein-protein interaction databases

BioGridi756078. 33 interactors.
STRINGi9606.ENSP00000342938.

Structurei

3D structure databases

ProteinModelPortaliB0FP48.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uroplakin-3 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IW5D. Eukaryota.
ENOG41123W4. LUCA.
GeneTreeiENSGT00510000048314.
HOGENOMiHOG000293265.
InParanoidiB0FP48.
OMAiVLIYTCF.
OrthoDBiEOG091G0HB1.
PhylomeDBiB0FP48.
TreeFamiTF336628.

Family and domain databases

InterProiView protein in InterPro
IPR024831. Uroplakin-3.
IPR024827. Uroplakin-3b-like.
PANTHERiPTHR15446. PTHR15446. 1 hit.
PTHR15446:SF19. PTHR15446:SF19. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

B0FP48-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNSWRLGPA IGLSAGQSQL LVSLLLLLTR VQPGTDVAAP EHISYVPQLS
60 70 80 90 100
NDTLAGRLTL STFTLEQPLG QFSSHNISDL DTIWLVVALS NATQSFTAPR
110 120 130 140 150
TNQDIPAPAN FSQRGYYLTL RANRVLYQTR GQLHVLRVGN DTHCQPTKIG
160 170 180 190 200
CNHPLPGPGP YRVKFLVMND EGPVAETKWS SDTRLQQAQA LRAVPGPQSP
210 220 230 240 250
GTVVIIAILS ILLAVLLTVL LAVLIYTCFN SCRSTSLSGP EEAGSVRRYT
260
THLAFSTPAE GAS
Length:263
Mass (Da):28,385
Last modified:February 26, 2008 - v1
Checksum:iCBA7419B03F7A57E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU341824 mRNA. Translation: ABY56115.1.
CCDSiCCDS47675.1.
RefSeqiNP_001107875.1. NM_001114403.2.
XP_016868385.1. XM_017012896.1.
UniGeneiHs.610255.

Genome annotation databases

EnsembliENST00000340457; ENSP00000342938; ENSG00000267368.
GeneIDi100134938.
107983993.
KEGGihsa:100134938.
hsa:107983993.

Similar proteinsi

Entry informationi

Entry nameiUPK3L_HUMAN
AccessioniPrimary (citable) accession number: B0FP48
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 26, 2009
Last sequence update: February 26, 2008
Last modified: August 30, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families