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B0FP48 (UPK3L_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uroplakin-3b-like protein
Gene names
Name:UPK3BL
Synonyms:UPLP
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length263 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Single-pass type I membrane protein Potential.

Sequence similarities

Belongs to the uroplakin-3 family.

Ontologies

Keywords
   Cellular componentMembrane
   DomainSignal
Transmembrane
Transmembrane helix
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3333 Potential
Chain34 – 263230Uroplakin-3b-like protein
PRO_0000375087

Regions

Topological domain34 – 204171Extracellular Potential
Transmembrane205 – 22521Helical; Potential
Topological domain226 – 26338Cytoplasmic Potential

Amino acid modifications

Glycosylation511N-linked (GlcNAc...) Potential
Glycosylation761N-linked (GlcNAc...) Potential
Glycosylation911N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
B0FP48 [UniParc].

Last modified February 26, 2008. Version 1.
Checksum: CBA7419B03F7A57E

FASTA26328,385
        10         20         30         40         50         60 
MDNSWRLGPA IGLSAGQSQL LVSLLLLLTR VQPGTDVAAP EHISYVPQLS NDTLAGRLTL 

        70         80         90        100        110        120 
STFTLEQPLG QFSSHNISDL DTIWLVVALS NATQSFTAPR TNQDIPAPAN FSQRGYYLTL 

       130        140        150        160        170        180 
RANRVLYQTR GQLHVLRVGN DTHCQPTKIG CNHPLPGPGP YRVKFLVMND EGPVAETKWS 

       190        200        210        220        230        240 
SDTRLQQAQA LRAVPGPQSP GTVVIIAILS ILLAVLLTVL LAVLIYTCFN SCRSTSLSGP 

       250        260 
EEAGSVRRYT THLAFSTPAE GAS 

« Hide

References

[1]"Human uroplakin-like protein."
Wistow G.
Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Eye.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
EU341824 mRNA. Translation: ABY56115.1.
CCDSCCDS47675.1.
RefSeqNP_001107875.1. NM_001114403.2.
XP_006716284.1. XM_006716221.1.
UniGeneHs.610255.

3D structure databases

ProteinModelPortalB0FP48.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid756078. 1 interaction.

PTM databases

PhosphoSiteB0FP48.

Proteomic databases

PaxDbB0FP48.
PRIDEB0FP48.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000340457; ENSP00000342938; ENSG00000267368.
GeneID100134938.
102724187.
KEGGhsa:100134938.
hsa:548644.
UCSCuc003uzw.2. human.

Organism-specific databases

CTD100134938.
GeneCardsGC07M102283.
HGNCHGNC:37278. UPK3BL.
HPAHPA011403.
neXtProtNX_B0FP48.
PharmGKBPA165618441.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG26593.
HOGENOMHOG000293265.
OMAETEWSSE.
PhylomeDBB0FP48.
TreeFamTF336628.

Gene expression databases

BgeeB0FP48.
GenevestigatorB0FP48.

Family and domain databases

InterProIPR024831. Uroplakin-3.
IPR024827. Uroplakin-3b-like.
[Graphical view]
PANTHERPTHR15446. PTHR15446. 1 hit.
PTHR15446:SF2. PTHR15446:SF2. 1 hit.
ProtoNetSearch...

Other

NextBio20774768.
PROB0FP48.

Entry information

Entry nameUPK3L_HUMAN
AccessionPrimary (citable) accession number: B0FP48
Entry history
Integrated into UniProtKB/Swiss-Prot: May 26, 2009
Last sequence update: February 26, 2008
Last modified: July 9, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 7

Human chromosome 7: entries, gene names and cross-references to MIM