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Protein
Submitted name:

Suppressor of cytokine signaling 8

Gene

SOCS8

Organism
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Biological processi

Enzyme and pathway databases

UniPathwayiUPA00143

Names & Taxonomyi

Protein namesi
Submitted name:
Suppressor of cytokine signaling 8Imported
Gene namesi
Name:SOCS8Imported
OrganismiTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)Imported
Taxonomic identifieri31033 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaTetraodontiformesTetradontoideaTetraodontidaeTakifugu

Subcellular locationi

Structurei

3D structure databases

ProteinModelPortaliB0EVN5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 129SH2InterPro annotationAdd BLAST82
Domaini165 – 213SOCS boxInterPro annotationAdd BLAST49

Keywords - Domaini

SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4566 Eukaryota
ENOG4111V4J LUCA
KOiK04701
OrthoDBiEOG091G0J75

Family and domain databases

CDDicd10718 SH2_CIS, 1 hit
Gene3Di3.30.505.10, 1 hit
InterProiView protein in InterPro
IPR028425 CIS
IPR035887 CIS_SH2
IPR000980 SH2
IPR036860 SH2_dom_sf
IPR001496 SOCS_box
IPR036036 SOCS_box-like_dom_sf
PANTHERiPTHR44649 PTHR44649, 1 hit
PfamiView protein in Pfam
PF00017 SH2, 1 hit
PF07525 SOCS_box, 1 hit
PRINTSiPR00401 SH2DOMAIN
SMARTiView protein in SMART
SM00252 SH2, 1 hit
SM00253 SOCS, 1 hit
SM00969 SOCS_box, 1 hit
SUPFAMiSSF158235 SSF158235, 1 hit
SSF55550 SSF55550, 1 hit
PROSITEiView protein in PROSITE
PS50001 SH2, 1 hit
PS50225 SOCS, 1 hit

Sequencei

Sequence statusi: Complete.

B0EVN5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVARAMSLFR QEKDKGSCCP PAPPAAWGPS EDYRSITATF RYLETSGWYW
60 70 80 90 100
GPTSVSDAQE ALLRKSEGTF LMRDSNHPKH MLTLSVKTCC GPTSVRIEYS
110 120 130 140 150
RGSFWLDSIA AGQLRTQTFP DVVSLVQHYM TLGHVPQSHT HSDMYQRAKP
160 170 180 190 200
DPSGDAARGC DVPLKLMFPL HKPGGFPSLR HLTRLAINRH ASCPDQLPLP
210
KLLLRYLQDY PFHI
Length:214
Mass (Da):24,055
Last modified:February 26, 2008 - v1
Checksum:iC44460B633F6BB15
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF195751 mRNA Translation: ABM68024.1
RefSeqiNP_001107630.1, NM_001114158.1
UniGeneiTru.4027

Genome annotation databases

GeneIDi100135423
KEGGitru:100135423

Similar proteinsi

Entry informationi

Entry nameiB0EVN5_TAKRU
AccessioniPrimary (citable) accession number: B0EVN5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 26, 2008
Last sequence update: February 26, 2008
Last modified: February 28, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health