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B0E6R0

- B0E6R0_ENTDS

UniProt

B0E6R0 - B0E6R0_ENTDS

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Protein
Histone deacetylase
Gene
EDI_183810
Organism
Entamoeba dispar (strain ATCC PRA-260 / SAW760)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotation

GO - Molecular functioni

  1. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: UniProtKB-EC
  2. NAD-dependent histone deacetylase activity (H3-K18 specific) Source: UniProtKB-EC
  3. NAD-dependent histone deacetylase activity (H3-K9 specific) Source: UniProtKB-EC
  4. NAD-dependent histone deacetylase activity (H4-K16 specific) Source: UniProtKB-EC

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulatorUniRule annotation, HydrolaseUniRule annotationSAAS annotations

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseUniRule annotation (EC:3.5.1.98UniRule annotation)
Gene namesi
ORF Names:EDI_183810Imported
OrganismiEntamoeba dispar (strain ATCC PRA-260 / SAW760)
Taxonomic identifieri370354 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaArchamoebaeEntamoebidaeEntamoeba
ProteomesiUP000008076: Unassembled WGS sequence

Organism-specific databases

EuPathDBiAmoebaDB:EDI_183810.

Subcellular locationi

Nucleus By similarity UniRule annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB0E6R0.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK06067.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiIPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
PRINTSiPR01270. HDASUPER.
PR01271. HISDACETLASE.

Sequencei

Sequence statusi: Complete.

B0E6R0-1 [UniParc]FASTAAdd to Basket

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MSRVCYFYDQ NVGEFDYGFG HPMKPLRNKL VHHLIMEYGI YKRLNIYKPW    50
RATNEQMEMF HSKEYIDFLQ RVTPEMALQP HFKKSLEEFN FTDDCPVFEG 100
LYPFVQTVVG SSLGCAMKIN ERAADICVNW SGGLHHAKKS QASGFCYIND 150
IVCAILELLK VHSRVLYIDI DHHHGDGVEE AFKATNRVMT FSLHKYGDNY 200
FPGTGDVDEI GIDEGKNYSI NVPLKDGIND EGYHRLFYPI IDRIMEVFQP 250
SVVVMQCGAD SLNGDRLGFF NLSIQGHCDC MKYVKKFGLP MILVGGGGYT 300
VSNTARCWCY ETAAACDLNI PDQIPINDYL EYYVPDMKIT ISTNPQMKNC 350
NSRNYIEDIL NKVMIILEDV GNSNLPIVQF TNPPRIDEHT IEMQIDEDQQ 400
DFNDVSNGFI RDIPLNIDSD EVIKMYTEPL PIYPKSKLFC TQNLKEFE 448
Length:448
Mass (Da):51,446
Last modified:February 26, 2008 - v1
Checksum:iD27A53FED078C439
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS547926 Genomic DNA. Translation: EDR29792.1.
RefSeqiXP_001734073.1. XM_001734021.1.

Genome annotation databases

GeneIDi5878967.
KEGGiedi:EDI_183810.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS547926 Genomic DNA. Translation: EDR29792.1 .
RefSeqi XP_001734073.1. XM_001734021.1.

3D structure databases

ProteinModelPortali B0E6R0.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 5878967.
KEGGi edi:EDI_183810.

Organism-specific databases

EuPathDBi AmoebaDB:EDI_183810.

Phylogenomic databases

KOi K06067.

Family and domain databases

Gene3Di 3.40.800.20. 1 hit.
InterProi IPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
[Graphical view ]
PANTHERi PTHR10625. PTHR10625. 1 hit.
Pfami PF00850. Hist_deacetyl. 1 hit.
[Graphical view ]
PIRSFi PIRSF037913. His_deacetylse_1. 1 hit.
PRINTSi PR01270. HDASUPER.
PR01271. HISDACETLASE.
ProtoNeti Search...

Publicationsi

  1. "Annotation of Entamoeba dispar SAW760."
    Lorenzi H., Inman J., Schobel S., Amedeo P., Caler E.
    Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC PRA-260 / SAW760.

Entry informationi

Entry nameiB0E6R0_ENTDS
AccessioniPrimary (citable) accession number: B0E6R0
Entry historyi
Integrated into UniProtKB/TrEMBL: February 26, 2008
Last sequence update: February 26, 2008
Last modified: May 14, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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