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B0CKC7 (PSD_BRUSI) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:BSUIS_A0469
OrganismBrucella suis (strain ATCC 23445 / NCTC 10510) [Complete proteome] [HAMAP]
Taxonomic identifier470137 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length232 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00664

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphatidylethanolamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functioncofactor binding

Inferred from electronic annotation. Source: InterPro

phosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 189189Phosphatidylserine decarboxylase beta chain By similarity
PRO_1000082918
Chain190 – 23243Phosphatidylserine decarboxylase alpha chain By similarity
PRO_1000082919

Sites

Site189 – 1902Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue1901Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
B0CKC7 [UniParc].

Last modified February 26, 2008. Version 1.
Checksum: 34915E274891E149

FASTA23225,794
        10         20         30         40         50         60 
MSLTDTIRNT FVPIHREGYP FIAGFFVVSL ILGWLWDPLF WIGMVLTVWC IYFYRDPERV 

        70         80         90        100        110        120 
TPMDDDLVIS PADGKVSFVG LAVPPAELDL GYEPMTRVSV FMNVFSVHIN RSPVRGKIDK 

       130        140        150        160        170        180 
VVHRPGKFLN AELDKASTEN ERNSVLIESP HGKVGVVQIA GLVARRIVCW SNQDDELSVG 

       190        200        210        220        230 
ERFGLIRFGS RVDVYLPSDA TVRVAVGQTA IAGETVLADY GTERGEPVVR IA

« Hide

References

[1]"Brucella suis ATCC 23445 whole genome shotgun sequencing project."
Setubal J.C., Bowns C., Boyle S., Crasta O.R., Czar M.J., Dharmanolla C., Gillespie J.J., Kenyon R.W., Lu J., Mane S., Mohapatra S., Nagrani S., Purkayastha A., Rajasimha H.K., Shallom J.M., Shallom S., Shukla M., Snyder E.E. expand/collapse author list , Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H., Bruce D., Detter C., Munk C., Brettin T.S.
Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 23445 / NCTC 10510.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000911 Genomic DNA. Translation: ABY37557.1.
RefSeqYP_001627127.1. NC_010169.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB0CKC7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5838929.
GenomeReviewsGene locus BSUIS_A0469 in contig CP000911_GR.
KEGGbmt:BSUIS_A0469.
PATRIC17868452. VBIBruSui83806_2027.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG541103.
OMAIFMSVFN.
ProtClustDBPRK05305.

Enzyme and pathway databases

BioCycBSUI470137:BSUIS_A0469-MONOMER.

Family and domain databases

HAMAPMF_00664. PS_decarb_type3.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR004428. PtdSer_deCO2ase-related.
[Graphical view]
KOK01613.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00164. PS_decarb_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_BRUSI
AccessionPrimary (citable) accession number: B0CKC7
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 26, 2008
Last modified: January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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