B0CJU9 (B0CJU9_BRUSI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
5-aminolevulinic acid synthase EMBL ABY37440.1

Gene names

Name:	hemA EMBL ABY37440.1
Ordered Locus Names:	BSUIS_A0348

Organism

Brucella suis (strain ATCC 23445 / NCTC 10510) [Complete proteome] [HAMAP]

Taxonomic identifier

470137 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	425 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU003693
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. RuleBase RU003693

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU003693
Molecular function	Transferase RuleBase RU003693
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrapyrrole biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	5-aminolevulinate synthase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring nitrogenous groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0CJU9 [UniParc]. Last modified February 26, 2008. Version 1. Checksum: D2D0C6CACEBA8A81	FASTA	425	46,156
	10 20 30 40 50 60 MDYRRFFEEA IDQLHAEKRY RVFADLERIV GRFPQAIWRN NGTAREITVW CSNDYLGMGH 70 80 90 100 110 120 HPDVIKAMCE TAGSAGSGAG GTRNISGNNH PLVELESELA DLHGKEAGLV FTSGFVSNEA 130 140 150 160 170 180 SISTIARLLP NCLILSDELN HASMIEGVRR SGAEKKIFRH NDVEHLEQLL KAADRSRAKL 190 200 210 220 230 240 IVFESVYSMD GDIAPIEKIA DLADKYNAMT YIDEVHAVGM YGAHGGGITE RDGLAHRIDI 250 260 270 280 290 300 IEGTLAKAFG ALGGYITGSR AIIDAVRSYA PGFIFTTSLP PAVAAAATAA IRHLKSSQAE 310 320 330 340 350 360 RDGQQRQAQR AKDVLSAAGL PVMPSQTHIV PILVGDPELC KKASDRLLEV HGIYIQPINY 370 380 390 400 410 420 PTVPRGTERL RITPSPLHDD KLIDGLKDAL LEVWNELGIP FAEPSAPQAA NSDRIIPLMV SKAGG

References

[1]

"Brucella suis ATCC 23445 whole genome shotgun sequencing project." Setubal J.C., Bowns C., Boyle S., Crasta O.R., Czar M.J., Dharmanolla C., Gillespie J.J., Kenyon R.W., Lu J., Mane S., Mohapatra S., Nagrani S., Purkayastha A., Rajasimha H.K., Shallom J.M., Shallom S., Shukla M., Snyder E.E. , Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H., Bruce D., Detter C., Munk C., Brettin T.S. Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000911 Genomic DNA. Translation: ABY37440.1.
RefSeq	YP_001627010.1. NC_010169.1.
3D structure databases
ProteinModelPortal	B0CJU9.
SMR	B0CJU9. Positions 2-394.
ModBase	Search...
Protein-protein interaction databases
STRING	B0CJU9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5838869.
GenomeReviews	Gene locus BSUIS_A0348 in contig CP000911_GR.
KEGG	bmt:BSUIS_A0348.
PATRIC	17868185. VBIBruSui83806_1893.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG649839.
OMA	HLKESNE.
ProtClustDB	PRK09064.
Family and domain databases
InterPro	IPR010961. 4pyrrol_synth_NH2levulA_synth. IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00643.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01821. 5aminolev_synth. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B0CJU9_BRUSI

Accession

Primary (citable) accession number: B0CJU9

Entry history

Integrated into UniProtKB/TrEMBL:	February 26, 2008
Last sequence update:	February 26, 2008
Last modified:	December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)