ID   COAA_BRUSI              Reviewed;         322 AA.
AC   B0CJI8;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 1.
DT   16-JUN-2009, entry version 9.
DE   RecName: Full=Pantothenate kinase;
DE            EC=2.7.1.33;
DE   AltName: Full=Pantothenic acid kinase;
GN   Name=coaA; OrderedLocusNames=BSUIS_A1929;
OS   Brucella suis (strain ATCC 23445 / NCTC 10510).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Brucellaceae; Brucella.
OX   NCBI_TaxID=470137;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Setubal J.C., Bowns C., Boyle S., Crasta O.R., Czar M.J.,
RA   Dharmanolla C., Gillespie J.J., Kenyon R.W., Lu J., Mane S.,
RA   Mohapatra S., Nagrani S., Purkayastha A., Rajasimha H.K.,
RA   Shallom J.M., Shallom S., Shukla M., Snyder E.E., Sobral B.W.,
RA   Wattam A.R., Will R., Williams K., Yoo H., Bruce D., Detter C.,
RA   Munk C., Brettin T.S.;
RT   "Brucella suis ATCC 23445 whole genome shotgun sequencing project.";
RL   Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: ATP + (R)-pantothenate = ADP + (R)-4'-
CC       phosphopantothenate.
CC   -!- PATHWAY: Cofactor biosynthesis; coenzyme A biosynthesis; coenzyme
CC       A from pantothenate: step 1/5.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the prokaryotic pantothenate kinase family.
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DR   EMBL; CP000911; ABY38940.1; -; Genomic_DNA.
DR   RefSeq; YP_001628510.1; -.
DR   GeneID; 5838155; -.
DR   GenomeReviews; CP000911_GR; BSUIS_A1929.
DR   KEGG; bmt:BSUIS_A1929; -.
DR   OMA; B0CJI8; PKVDLIT.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004594; F:pantothenate kinase activity; IEA:HAMAP.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00215; -; 1.
DR   InterPro; IPR004566; PanK_bact.
DR   PANTHER; PTHR10285:SF7; PanK_bact; 1.
DR   PIRSF; PIRSF000545; Pantothenate_kin; 1.
DR   TIGRFAMs; TIGR00554; panK_bact; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Coenzyme A biosynthesis; Complete proteome; Cytoplasm;
KW   Kinase; Nucleotide-binding; Transferase.
FT   CHAIN         1    322       Pantothenate kinase.
FT                                /FTId=PRO_1000078053.
FT   NP_BIND     100    107       ATP (Potential).
SQ   SEQUENCE   322 AA;  37477 MW;  D3EFE78CC7FC7D0B CRC64;
     MWEKVDQLTP SRYSPYRFFS AQEWAAFRAD TPLTLTYEEV KRLRSLGDPI DLDEVRRIYL
     SLSRLLYAHV EASQLLFRQR QQFLNMEESY KTPFIIGVAG SVAVGKSTMA RILKELLARW
     PSSPKVDLVT TDGFLYPNAV LREQNMMERK GFPESYDIGA VLRFLSAIKA GMSRVRAPLY
     SHLSYDVLPG EYQIVDKPDI LIFEGINVLQ VRDLPEDGKM VPFVSDFFDF SIYIDADPRL
     IHKWYIDRFM RLRETAFRDP QSFFHRYSQL SQEAARSIAE GLWQNINLKN LNENILPTRP
     RADLILRKGS DHLIEEVALR KI
//