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B0CF69 (B0CF69_ACAM1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
GTP cyclohydrolase 1 2 HAMAP MF_00223
EC=3.5.4.16 HAMAP MF_00223
Alternative name(s):
GTP cyclohydrolase I 2 HAMAP MF_00223
Gene names
Name:folE EMBL ABW30585.1
Synonyms:folE2 HAMAP MF_00223
Ordered Locus Names:AM1_5635
OrganismAcaryochloris marina (strain MBIC 11017) [Complete proteome] [HAMAP]
Taxonomic identifier329726 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Acaryochloris

Protein attributes

Sequence length232 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate. HAMAP MF_00223 SAAS SAAS001474

Pathway

Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1. HAMAP MF_00223 SAAS SAAS001474

Subunit structure

Homopolymer By similarity. HAMAP MF_00223

Sequence similarities

Belongs to the GTP cyclohydrolase I family. HAMAP MF_00223

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1191Zinc By similarity HAMAP MF_00223
Metal binding1221Zinc By similarity HAMAP MF_00223
Metal binding1901Zinc By similarity HAMAP MF_00223

Sequences

Sequence LengthMass (Da)Tools
B0CF69 [UniParc].

Last modified February 26, 2008. Version 1.
Checksum: 1ED83ABD007708AF

FASTA23226,209
        10         20         30         40         50         60 
MTTFSPKPSD QANSSMNSTS NNAQLRPDRS LSQRAKEKET HRQASKEEMM GAVETMLLGV 

        70         80         90        100        110        120 
GEDPEREGLL KTPKRVAEAM RFLTSGYQQS LEDLVNNAIF DEGHDEMVLV RDIDAFSLCE 

       130        140        150        160        170        180 
HHMLPFIGKA HVAYIPNQKV IGLSKLARIV EMYSRRLQVQ ERLTRQIAEA VQTALEPKGV 

       190        200        210        220        230 
AVVMEASHMC MVMRGVQKPG SWTVTSSMIG VFQDDHKTRE EFLNLIRHPH NF

« Hide

References

[1]"Niche adaptation and genome expansion in the chlorophyll d-producing cyanobacterium Acaryochloris marina."
Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J., Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y., Taylor H.L. expand/collapse author list , Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M., Blankenship R.E., Touchman J.W.
Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008) [PubMed: 18252824] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000828 Genomic DNA. Translation: ABW30585.1.
RefSeqYP_001519904.1. NC_009925.1.

3D structure databases

ProteinModelPortalB0CF69.
SMRB0CF69. Positions 49-227.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0CF69.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5684425.
GenomeReviewsGene locus AM1_5635 in contig CP000828_GR.
KEGGamr:AM1_5635.
PATRIC20625252. VBIAcaMar40141_5231.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG370191.
OMAKQIATAM.
PhylomeDBB0CF69.

Family and domain databases

HAMAPMF_00223. FolE.
[Tree]
InterProIPR001474. GTP_CycHdrlase_I.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
IPR018234. GTP_CycHdrlase_I_CS.
[Graphical view]
KOK01495.
PANTHERPTHR11109. GTP_cyclohydro_I. 1 hit.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
TIGRFAMsTIGR00063. FolE. 1 hit.
PROSITEPS00859. GTP_CYCLOHYDROL_1_1. 1 hit.
PS00860. GTP_CYCLOHYDROL_1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB0CF69_ACAM1
AccessionPrimary (citable) accession number: B0CF69
Entry history
Integrated into UniProtKB/TrEMBL: February 26, 2008
Last sequence update: February 26, 2008
Last modified: December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info