B0CEQ4 (SYGA_ACAM1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycine--tRNA ligase alpha subunit
EC=6.1.1.14

Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	AM1_3163

Organism

Acaryochloris marina (strain MBIC 11017) [Complete proteome] [HAMAP]

Taxonomic identifier

329726 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Acaryochloris

Protein attributes

Sequence length	293 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_00254.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glycine-tRNA ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 293	293	Glycine--tRNA ligase alpha subunit HAMAP MF_00254		PRO_1000078520

Sequences

	Sequence		Length	Mass (Da)
	B0CEQ4 [UniParc]. Last modified February 26, 2008. Version 1. Checksum: FB73B9F6083C7823	FASTA	293	33,858
	10 20 30 40 50 60 MNFQSVIAKL HEFWSDRGCL IVQPYDIEKG AGTKSPHTFL RSLGPEPWAV AYVEPCRRPA 70 80 90 100 110 120 DGRYGENPNR YQYYYQYQVL VKPSPDDIQD IYLDSLRVLG IQPEDHDIRF VEDNWEDAAV 130 140 150 160 170 180 GAWGVGWEVW LDGMEVTQFT YFQQCGGLDC RPVSIELTYG LERLTMYLQE TDAIAKIDWN 190 200 210 220 230 240 GTLTYGDVHL QGEIEQSTYN FEASNPELLF QLFSLYEQEA LQLIEKQLVL PGLDYVLKCS 250 260 270 280 290 HTFNLLDARG VISVTERTRY IGRIRQMARQ VAQLYLQQRE ELGFPLLKTQ SVS

References

[1]

"Niche adaptation and genome expansion in the chlorophyll d-producing cyanobacterium Acaryochloris marina." Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J., Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y., Taylor H.L. , Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M., Blankenship R.E., Touchman J.W. Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008) [PubMed: 18252824] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MBIC 11017.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000828 Genomic DNA. Translation: ABW28159.1.
RefSeq	YP_001517475.1. NC_009925.1.
3D structure databases
ProteinModelPortal	B0CEQ4.
SMR	B0CEQ4. Positions 1-281.
ModBase	Search...
Protein-protein interaction databases
STRING	B0CEQ4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5681971.
GenomeReviews	Gene locus AM1_3163 in contig CP000828_GR.
KEGG	amr:AM1_3163.
PATRIC	20620596. VBIAcaMar40141_2926.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG285316.
OMA	CRRPTDG.
PhylomeDB	B0CEQ4.
ProtClustDB	PRK09348.
Enzyme and pathway databases
BioCyc	AMAR329726:AM1_3163-MONOMER.
Family and domain databases
HAMAP	MF_00254. Gly_tRNA_synth_alpha. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
KO	K01878.
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
TIGRFAMs	TIGR00388. GlyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_ACAM1

Accession

Primary (citable) accession number: B0CEQ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	February 26, 2008
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program