ID   B0CE49_ACAM1            Unreviewed;       880 AA.
AC   B0CE49;
DT   26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   26-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 84.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor, putative {ECO:0000313|EMBL:ABW30523.1};
GN   OrderedLocusNames=AM1_5569 {ECO:0000313|EMBL:ABW30523.1};
OS   Acaryochloris marina (strain MBIC 11017).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Acaryochloridales;
OC   Acaryochloridaceae; Acaryochloris.
OX   NCBI_TaxID=329726 {ECO:0000313|EMBL:ABW30523.1, ECO:0000313|Proteomes:UP000000268};
RN   [1] {ECO:0000313|EMBL:ABW30523.1, ECO:0000313|Proteomes:UP000000268}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MBIC 11017 {ECO:0000313|Proteomes:UP000000268};
RX   PubMed=18252824; DOI=10.1073/pnas.0709772105;
RA   Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J.,
RA   Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D.,
RA   Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y.,
RA   Taylor H.L., Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M.,
RA   Blankenship R.E., Touchman J.W.;
RT   "Niche adaptation and genome expansion in the chlorophyll d-producing
RT   cyanobacterium Acaryochloris marina.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008).
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DR   EMBL; CP000828; ABW30523.1; -; Genomic_DNA.
DR   RefSeq; WP_012165743.1; NC_009925.1.
DR   AlphaFoldDB; B0CE49; -.
DR   STRING; 329726.AM1_5569; -.
DR   KEGG; amr:AM1_5569; -.
DR   eggNOG; COG1716; Bacteria.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_20_3; -.
DR   OrthoDB; 442691at2; -.
DR   Proteomes; UP000000268; Chromosome.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 2.60.200.20; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00498; FHA; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00240; FHA; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 1.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000268}.
FT   DOMAIN          62..122
FT                   /note="FHA"
FT                   /evidence="ECO:0000259|PROSITE:PS50006"
FT   DOMAIN          310..382
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          386..438
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          471..604
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          613..868
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   880 AA;  99742 MW;  4591D32A4C0230E4 CRC64;
     MLHSPNSPEE EYTIAFSRKD KKAASTARNV EALIHPNRQT YHILAIEIDQ KKQLISLEDA
     TYTIGRHQAN AIVLDDQTVS RNHAFLLRIC DVNTKQHSFR IIDGDLNGKR SQNGLWVNGK
     RCFIHDLQDH DVISFGERIH ATYVSTSNLN DPRIGIGKNH VQSLPIPLPK PNLTLGSTLF
     HKATVGNPQG IQDSLVPQQS GDAAFVRLSS FPELTPLPII ETDLDGNITY INPAASNKFP
     ELRTIKRHPL TDGLYEKLVQ EQSEYVVREM EIGSSIYEQA IYCILQNGLI RSYLIEITQH
     RRTEQQLRLS EARYAAAAKG ANDGLWDWDL HGNTIYFSDR WKAMLGFSEE EIGASPDEWF
     NRIHPQDQDR VTEDLSAHLR GDTPQFECEY RILHSNGEYL WFKGRGLALR NDQNQAFRIA
     GSQTDVTAYY STRAQLEFKA QHDEMTQLPN RVLFMERLTH AFRMAKHQQS RLFAVLFLDL
     DRFKIINDSL GHRVGDQLLI EVSKRLQQCL RKQDTIARFG GDEFAILLDT VEDADEAIHV
     AQRILQALKA KISLEEHEVY TSASIGITVS SPDYQAPEEL LQDSDTAMYR AKKQGKNCFE
     VFSSGMRAQV NSQLQLETDL QRAISNNELH LVYQPIVDLN TENIVGFEAL LRWNHPERGL
     VPPSEFIPVA EDAGLMVSID WWVLTEACQQ MAHWLNIYPG STELTINVNI SAHQFLQSTF
     CEKVNAIIQE TGMKPHHLKL EITEGVILSN APNISEQLNN LKKLGIHLAI DDFGTGYSSL
     SYLYAFPLDV LKVDYSFVSR MDQDNGLAIV RTIVNLGQNL NMKVVAEGVE TKIQQEYLQE
     MGCEFAQGYL FSRPLKKESV ESILTNKNLP HIPAIPVTTA
//