Reviewed, UniProtKB/Swiss-Prot B0CD95 (PGK_ACAM1)

Names and origin

Protein names

Recommended name:
    Phosphoglycerate kinase
    EC=2.7.2.3

Gene names

Name:	pgk
Ordered Locus Names:	AM1_0637

Organism

Acaryochloris marina (strain MBIC 11017) [Complete proteome] [HAMAP]

Taxonomic identifier

329726 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Acaryochloris

Protein attributes

Sequence length	401 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP MF_00145
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP MF_00145
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglycerate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 401	401	Phosphoglycerate kinase HAMAP MF_00145		PRO_1000076577
Regions
	Nucleotide binding	357 – 360	4	ATP By similarity
	Region	24 – 26	3	Substrate binding By similarity
	Region	63 – 66	4	Substrate binding By similarity
Sites
	Binding site	40	1	Substrate By similarity
	Binding site	122	1	Substrate By similarity
	Binding site	155	1	Substrate By similarity
	Binding site	206	1	ATP By similarity
	Binding site	297	1	ATP; via carbonyl oxygen By similarity
	Binding site	328	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	B0CD95-1 [UniParc]. Last modified February 26, 2008. Version 1. Checksum: 7D414EB97EC3D54D	FASTA	401	41,862
	10 20 30 40 50 60 MSKKTIANLT SADLSGKRVL VRADFNVPLD GDGKITDDTR IRAALPTIQD LTSKGAKVIL 70 80 90 100 110 120 ASHFGRPKGQ VNESMRLTPV AARLSELLGQ AVTKCDDCIG DEVAAKVGAL QNGQVALLEN 130 140 150 160 170 180 VRFHSGEEAN DPEFARQLAS VADLYVNDAF GTAHRAHAST EGVTHHLSPS VAGYLIEKEL 190 200 210 220 230 240 KYLQAAIEGP QRPLAAIVGG SKVSSKIGVI ETLLDKVDKL LIGGGMIFTF YKARGLAVGK 250 260 270 280 290 300 SLVEEDKLDL ARTLEAKAKE KGVALLLPSD VVVADNFAAD ANAQTVSINN IPDGWMGLDI 310 320 330 340 350 360 GPNSVKEFQA ALSDCKTVIW NGPMGVFEFD KFAAGTDAVA HSLAAITETG ADTIIGGGDS 370 380 390 400 VAAVEKVGVA EKMSHISTGG GASLELLEGK VLPGIAALDE A

References

[1]

"Niche adaptation and genome expansion in the chlorophyll d-producing cyanobacterium Acaryochloris marina." Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J., Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y., Taylor H.L. , Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M., Blankenship R.E., Touchman J.W. Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008) [PubMed: 18252824] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000828 Genomic DNA. Translation: ABW25686.1.
RefSeq	YP_001515000.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5679465.
GenomeReviews	Gene locus AM1_0637 in contig CP000828_GR.
KEGG	amr:AM1_0637.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	CLENTRF.
Family and domain databases
HAMAP	MF_00145. [Tree]
InterPro	IPR001576. Phosphoglycerate_kinase. IPR015901. Phosphoglycerate_kinase_C. IPR015911. Phosphoglycerate_kinase_CS. IPR015824. Phosphoglycerate_kinase_N. [Graphical view]
Gene3D	G3DSA:3.40.50.1270. Phosphoglycerate_kinase_C. 1 hit. G3DSA:3.40.50.1260. Phosphoglycerate_kinase_N. 1 hit.
PANTHER	PTHR11406. PGK. 1 hit.
Pfam	PF00162. PGK. 1 hit. [Graphical view]
PRINTS	PR00477. PHGLYCKINASE.
PROSITE	PS00111. PGLYCERATE_KINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PGK_ACAM1

Accession

Primary (citable) accession number: B0CD95

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	February 26, 2008
Last modified:	November 3, 2009
This is version 11 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)