B0CD42 (B0CD42_ACAM1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase EMBL ABW25633.1

Gene names

Name:	lpxA EMBL ABW25633.1
Ordered Locus Names:	AM1_0583

Organism

Acaryochloris marina (strain MBIC 11017) [Complete proteome] [HAMAP]

Taxonomic identifier

329726 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Acaryochloris

Protein attributes

Sequence length	271 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS010137
Catalytic activity	(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetylglucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine. SAAS SAAS010137
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6. SAAS SAAS010137
Subunit structure	Homotrimer By similarity. SAAS SAAS010137
Subcellular location	Cytoplasm By similarity SAAS SAAS010137.

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS010137 Lipid synthesis
Cellular component	Cytoplasm SAAS SAAS010137
Domain	Repeat SAAS SAAS010137
Molecular function	Acyltransferase SAAS SAAS010137 EMBL ABW25633.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0CD42 [UniParc]. Last modified February 26, 2008. Version 1. Checksum: 16AE32D2BA2CBD8D	FASTA	271	29,852
	10 20 30 40 50 60 MTDLIHPTAV IHPQATLHQT VQIGAYAVIG KQVKLGPGTQ VGHHAVIEGW TEIGADNHIF 70 80 90 100 110 120 PGVVIGMEPQ DRNFRGEQSG VKICDRNQIR EYVTIHRASG DQQFTTIGSD NLLMANVHIG 130 140 150 160 170 180 HNCHIADRVV IANSVALSGH VQVESQANIS GVLGIHQFVH VGQLAMIGGM SRITRDVPPL 190 200 210 220 230 240 MLVEGNPAHV RALNQVGLQR HGVYDLLQGE MRGLLKQAFR YLYRSNLQLE VALDQVESLS 250 260 270 EHPLIQHLCQ FMRAAQTRRG LTPGRQRWAS V

References

[1]

"Niche adaptation and genome expansion in the chlorophyll d-producing cyanobacterium Acaryochloris marina." Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J., Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y., Taylor H.L. , Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M., Blankenship R.E., Touchman J.W. Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008) [PubMed: 18252824] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000828 Genomic DNA. Translation: ABW25633.1.
RefSeq	YP_001514947.1. NC_009925.1.
3D structure databases
ProteinModelPortal	B0CD42.
ModBase	Search...
Protein-protein interaction databases
STRING	B0CD42.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5679411.
GenomeReviews	Gene locus AM1_0583 in contig CP000828_GR.
KEGG	amr:AM1_0583.
PATRIC	20615694. VBIAcaMar40141_0499.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG659295.
OMA	GDKNLLM.
PhylomeDB	B0CD42.
Family and domain databases
InterPro	IPR001451. Hexapep_transf. IPR010137. Lipid_A_lpxA. IPR011004. Trimer_LpxA-like. [Graphical view]
KO	K00677.
Pfam	PF00132. Hexapep. 2 hits. [Graphical view]
PIRSF	PIRSF000456. UDP-GlcNAc_acltr. 1 hit.
SUPFAM	SSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMs	TIGR01852. Lipid_A_lpxA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B0CD42_ACAM1

Accession

Primary (citable) accession number: B0CD42

Entry history

Integrated into UniProtKB/TrEMBL:	February 26, 2008
Last sequence update:	February 26, 2008
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)