B0CD41 (B0CD41_ACAM1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL ABW25632.1

Gene names

Name:	lpxB EMBL ABW25632.1
Ordered Locus Names:	AM1_0581

Organism

Acaryochloris marina (strain MBIC 11017) [Complete proteome] [HAMAP]

Taxonomic identifier

329726 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Acaryochloris

Protein attributes

Sequence length	391 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0CD41 [UniParc]. Last modified February 26, 2008. Version 1. Checksum: 89BB2C94054EFD9A	FASTA	391	43,305
	10 20 30 40 50 60 MDRPYRIFIS TGEVSGDLQG SLLIPALMAE AQSRGYALEI WALGGPRMAA VGARLLGDTS 70 80 90 100 110 120 QIGAIGPVNA LPFVWPTLKL HKQVMDQFKQ VPPDLTVLID YIGPNLRLGQ HLKQACPNPV 130 140 150 160 170 180 VYYIAPSEWV WSQGLGVTRQ VVDLSDKMLA IFPQEATYYQ EMGADINWVG HPLVDHIHQF 190 200 210 220 230 240 PPREQARQQL GLHPHQPMMA LMPASRHQEL AHLLPVMLTA AQQICRQVPD IQFWIPLALP 250 260 270 280 290 300 AYRGEVTQAL QRTGLPISLF PDSQTVVAAA DVVITKSGTA NLEAALLNVP QVVVYRVGAI 310 320 330 340 350 360 SAWLYQHLLH FEVEFISPVN LVVGREIVPE LLQQEVTPEK IAELAYSLLE KGEARHTMMA 370 380 390 GYQELRSHLG LPGVLQRAAE AILNVLEQSL R

References

[1]

"Niche adaptation and genome expansion in the chlorophyll d-producing cyanobacterium Acaryochloris marina." Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J., Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y., Taylor H.L. , Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M., Blankenship R.E., Touchman J.W. Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008) [PubMed: 18252824] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000828 Genomic DNA. Translation: ABW25632.1.
RefSeq	YP_001514946.1. NC_009925.1.
3D structure databases
ProteinModelPortal	B0CD41.
ModBase	Search...
Protein-protein interaction databases
STRING	B0CD41.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5679410.
GenomeReviews	Gene locus AM1_0581 in contig CP000828_GR.
KEGG	amr:AM1_0581.
PATRIC	20615692. VBIAcaMar40141_0498.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG584837.
OMA	PDFNLGL.
ProtClustDB	PRK00025.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B0CD41_ACAM1

Accession

Primary (citable) accession number: B0CD41

Entry history

Integrated into UniProtKB/TrEMBL:	February 26, 2008
Last sequence update:	February 26, 2008
Last modified:	December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)