ID   B0CD40_ACAM1            Unreviewed;      1197 AA.
AC   B0CD40;
DT   26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   26-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 81.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor {ECO:0000313|EMBL:ABW25631.1};
GN   OrderedLocusNames=AM1_0582 {ECO:0000313|EMBL:ABW25631.1};
OS   Acaryochloris marina (strain MBIC 11017).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Acaryochloridales;
OC   Acaryochloridaceae; Acaryochloris.
OX   NCBI_TaxID=329726 {ECO:0000313|EMBL:ABW25631.1, ECO:0000313|Proteomes:UP000000268};
RN   [1] {ECO:0000313|EMBL:ABW25631.1, ECO:0000313|Proteomes:UP000000268}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MBIC 11017 {ECO:0000313|Proteomes:UP000000268};
RX   PubMed=18252824; DOI=10.1073/pnas.0709772105;
RA   Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J.,
RA   Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D.,
RA   Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y.,
RA   Taylor H.L., Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M.,
RA   Blankenship R.E., Touchman J.W.;
RT   "Niche adaptation and genome expansion in the chlorophyll d-producing
RT   cyanobacterium Acaryochloris marina.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008).
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DR   EMBL; CP000828; ABW25631.1; -; Genomic_DNA.
DR   RefSeq; WP_012161230.1; NC_009925.1.
DR   AlphaFoldDB; B0CD40; -.
DR   STRING; 329726.AM1_0582; -.
DR   KEGG; amr:AM1_0582; -.
DR   eggNOG; COG1716; Bacteria.
DR   eggNOG; COG3829; Bacteria.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_271123_0_0_3; -.
DR   OrthoDB; 9759607at2; -.
DR   Proteomes; UP000000268; Chromosome.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd00060; FHA; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 2.
DR   Gene3D; 2.60.200.20; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00498; FHA; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08447; PAS_3; 2.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00240; FHA; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00091; PAS; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000268}.
FT   DOMAIN          343..413
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          417..469
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          502..635
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          644..898
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
FT   DOMAIN          933..983
FT                   /note="FHA"
FT                   /evidence="ECO:0000259|PROSITE:PS50006"
SQ   SEQUENCE   1197 AA;  134320 MW;  A98F875DEC391AAA CRC64;
     MSVIQQFWNQ LTIVPRQLSL GLKTLLDQLE SPTLALPEVA QSQATGNHFL LAYQKLADLD
     SQHLSLSERL QKSVEILSET LGFAIVVLDF YDPSQQTLQF QAGTITHLNH EDEGTLQRLN
     HQASQVLGAS RPLVLVDDQG VTNQTHLASY LPPSALLKTV LQLPLATNHT VLGMLTLGSP
     ELLPDANMLC LWGKQVASFL AWLIQAERAN TCFNNVQERF SLVASSFRGC FYDWDIAIDS
     ILQFTKTNEE QAAKPHAPRQ FSVPEWLDQI HPEDRHLLET LIDQDFQGED QFELEYRWQS
     DGQPFMCDRG VIQRDAQGVP IRVVGVLTNI ADFKRLEENA QQQIDHYQTL LADISIVIFK
     TDLAGHWTYL NPAWSKLTGI SLEDSLGKPI WDFVHPDDRP GLQEAFHNLV EQTSESYNHE
     LRFFCQQGGC AWVVVHNHVI RAEDGTCIGT AGTLEDASER KQTEQALLHD ALHDGLTQLP
     NRVLFMDRLE QACRSFQRHP DEIFAVLFLD LDRFKIINDT LGHMVGDQLL VAVAHRLQTC
     LRPEDTVARL GGDEFTLLLP NIDQAEDAMH ISDRILQSLK EPFTLDHTEV FITVSIGIAM
     SGNPEQKPDD LLRHADIALY RAKANGKGCY AVFSPEMPLQ PLAQVQIETE VRQALDDEEF
     RLYCQPVHSL ENNEVWGFTL QMYWQHPHKG VLPSFEFLPS VTDTGLQRSL GWWVLRKACA
     QLHQWQRMPT EQPLSIWVAV SEAQLTSSNF LSKFERLLEK HDINPQHLVL ELPPSLWPRP
     SKKVLAHLQD VHSRGVQLAR VQDNQDFDWL SGEESLPVDW VKLSSTLLGN LDQQGYLESI
     HSLFILAASA EIKMLADGIQ TPKQRLLMSA LKCDYGQGHN FTDPIPAHAA DPWLEPSYSQ
     PLDSMNPSSS MSLLIIYSPI GQSQVPLVGK QSWTIGRSPD NSIVLPDRWA SRNHAQLRAT
     DAGEFFLIDL GSGNGSVVNG ERVTMPVALK DGDLITIGHS QLEFHHRTRE SALSAIETAP
     KNVLMMQASH MQGQVWKEAL SSQGISLTWL NENIDLAQYL TQSIKSGQGV PDLLLLDMTI
     LKPNPYSFCR WCHNLHPTLK IILTSGTRTF VPASERKWAT HQGASELIAA FDEGSIFSNL
     IDVMAKVRVV LATINWRPIE QGSLSSALLA IKPSLTTSTF NSRQTIIGEL PADLEST
//