Reviewed, UniProtKB/Swiss-Prot B0CCT9 (G6PI_ACAM1)

Names and origin

Protein names

Recommended name:
    Glucose-6-phosphate isomerase
      Short name=GPI
    EC=5.3.1.9
Alternative name(s):
    Phosphoglucose isomerase
      Short name=PGI
    Phosphohexose isomerase
      Short name=PHI

Gene names

Name:	pgi
Ordered Locus Names:	AM1_4272

Organism

Acaryochloris marina (strain MBIC 11017) [Complete proteome] [HAMAP]

Taxonomic identifier

329726 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Acaryochloris

Protein attributes

Sequence length	529 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473
Pathway	Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_00473 Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: HAMAP glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 529	529	Glucose-6-phosphate isomerase HAMAP MF_00473		PRO_1000081228
Sites
	Active site	322	1	Proton donor By similarity
	Active site	351	1	By similarity
	Active site	455	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	B0CCT9-1 [UniParc]. Last modified February 26, 2008. Version 1. Checksum: 148311009FE8D76C	FASTA	529	58,213
	10 20 30 40 50 60 MDAAALWQRY QDWLYYHEQL GIYVDISRMS FDDAFVERLE PKFVKAFKEM DALEAGAIAN 70 80 90 100 110 120 PDENRMVGHY WLRDSNLAPT PELKKEIITT LEKIEAFAAD VHAGRIKPAT APRFTDVISI 130 140 150 160 170 180 GIGGSSLGPQ FVSQALAVLH PALELHFIDN TDPAGIDYIL DRVQDRLDTT LVVTISKSGG 190 200 210 220 230 240 TPETRNGMLE AKNRFKNLGL DFPKHAVAVT GYGSKLAQIA EEEGWLAMLP MHDWVGGRTS 250 260 270 280 290 300 ELSAVGLVPA SLQGIAIREM LAGAKAMDEA TRVHDLKTNP AALLALSWYF AGEGAGKKDM 310 320 330 340 350 360 VILPYKDSLM LFSRYLQQLV MESLGKEKDL DDKIVHQGIA VYGNKGSTDQ HAYVQELREG 370 380 390 400 410 420 IPNFFLTFIE VLKDRDGTRF EVEPGVTSGD YLSGFLLGTR EALYEKRRDS ITVTLPEVTS 430 440 450 460 470 480 KQVGALIALY ERAVGLYASL INVNAYHQPG VEAGKKAATD TIALQNKIVQ ILRNTLTPLP 490 500 510 520 ITSLADKAEA PDKIETVYKI VRHLAANKRG VELYGNPAEP GSLQVTLKG

References

[1]

"Niche adaptation and genome expansion in the chlorophyll d-producing cyanobacterium Acaryochloris marina." Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J., Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y., Taylor H.L. , Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M., Blankenship R.E., Touchman J.W. Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008) [PubMed: 18252824] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000828 Genomic DNA. Translation: ABW29251.1.
RefSeq	YP_001518568.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5683075.
GenomeReviews	Gene locus AM1_4272 in contig CP000828_GR.
KEGG	amr:AM1_4272.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	B0CCT9. PYSNDLA.
Family and domain databases
HAMAP	MF_00473. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. False negative. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI_ACAM1

Accession

Primary (citable) accession number: B0CCT9

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	February 26, 2008
Last modified:	June 16, 2009
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)