ID   B0CC32_ACAM1            Unreviewed;       886 AA.
AC   B0CC32;
DT   26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   26-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 76.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase, putative {ECO:0000313|EMBL:ABW25574.1};
GN   OrderedLocusNames=AM1_0522 {ECO:0000313|EMBL:ABW25574.1};
OS   Acaryochloris marina (strain MBIC 11017).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Acaryochloridales;
OC   Acaryochloridaceae; Acaryochloris.
OX   NCBI_TaxID=329726 {ECO:0000313|EMBL:ABW25574.1, ECO:0000313|Proteomes:UP000000268};
RN   [1] {ECO:0000313|EMBL:ABW25574.1, ECO:0000313|Proteomes:UP000000268}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MBIC 11017 {ECO:0000313|Proteomes:UP000000268};
RX   PubMed=18252824; DOI=10.1073/pnas.0709772105;
RA   Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J.,
RA   Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D.,
RA   Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y.,
RA   Taylor H.L., Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M.,
RA   Blankenship R.E., Touchman J.W.;
RT   "Niche adaptation and genome expansion in the chlorophyll d-producing
RT   cyanobacterium Acaryochloris marina.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CP000828; ABW25574.1; -; Genomic_DNA.
DR   RefSeq; WP_012161178.1; NC_009925.1.
DR   AlphaFoldDB; B0CC32; -.
DR   STRING; 329726.AM1_0522; -.
DR   KEGG; amr:AM1_0522; -.
DR   eggNOG; COG5000; Bacteria.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_78_2_3; -.
DR   OrthoDB; 543801at2; -.
DR   Proteomes; UP000000268; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd12913; PDC1_MCP_like; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000268};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        352..375
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          372..424
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          482..615
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          624..880
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
FT   COILED          416..446
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   886 AA;  100001 MW;  F29287380D315E86 CRC64;
     MEQLSRWKKI RFPLHRALPL RFTLIVLFVL QLLVSVGLVG YLSLRNGEEA IEDLANQLMS
     ETGDRISERL NIYLLTPHQV NQLNEDALDM GQLQLNDLQS MERHFWRQSQ VFKLISYIQF
     GNLQGEFVGL AVNDDGTLTY QVTEETGALQ TYSIDTKGDR KQYLKISPNF DARQRPWYIV
     PQQADKPAWT EIYPWVSPPT LAITLGQPYY DAQGKFQGIL ATDLSLAQIS DFLKELSLCD
     SSRTFILERS GDIVATSSNE LPFVWRNHKP GRLMATHSED GVVQATAAYL AKQAGGLQQI
     NARRQIQFSI KGQRYFLQVT PLQDQHGLDW LSVLVIPESS FMAQIDANTR TTLLLCFLAL
     GCAIYLGVCT ASWIARPILR FSQASQAISS GQFDQTVAVK GFKEIGVLQQ SFNRMAEKLQ
     ATFSDLEAAN LALTKEVAER QRAEEQFKHL ALHDPLTGFP NRAFFMEQLE RAVKQTQRHS
     QYLFAVLFID LDRFKIVNDS LGHEVGDQLL GAIAHQLHSL VRATDIVARL GGDEFVILLE
     PIEEVNDAVR VADRIVQELS APIDLSNRQV FISASVGIAL SSPDYSQATD ILRDADIAMY
     RAKNRGKACF EIFNERMYTQ ALDRLQLEND LRQAIANQQL QVFYQPIVNI QTGKLSGFEA
     LGRWPHPQRG FIPPTEFIPI AEETGLIIPL GEWILQSACQ QMATWLQTYP SAVKYTISVN
     MSIKQLKDPN LLTKVDRALE QSGLNRHQLS LELTESILME NVIELKVILN QLKERGIQLS
     IDDFGTGYSS LSYLHLFPFN TIKIDQSFIT RIGAQGENQE IIETIINLAS QLNMDAISEG
     VESKQQLNYL KKLLCQKAQG NYFSQPLSSD AAEVFILNNP QLIQVH
//