Skip Header

Contribute Send feedback
Read comments (?) or add your own

B0CBS9 (AROB_ACAM1) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:AM1_5373
OrganismAcaryochloris marina (strain MBIC 11017) [Complete proteome] [HAMAP]
Taxonomic identifier329726 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Acaryochloris

Protein attributes

Sequence length372 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm By similarity HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3723723-dehydroquinate synthase HAMAP MF_00110
PRO_1000202904

Sequences

Sequence LengthMass (Da)Tools
B0CBS9 [UniParc].

Last modified February 26, 2008. Version 1.
Checksum: 630275E7B4568EA3

FASTA37240,821
        10         20         30         40         50         60 
MQQTFIPVPL PQQPYQIAIA SGGLTQLGSW LQDRSLQSVK LGQKVLVVSN PQIWKHYGEI 

        70         80         90        100        110        120 
VQDSLAQAGF QVEHFLLPAG ERYKTPRSIQ KIYDYALDLK LERSSTLVAL GGGVIGDMTG 

       130        140        150        160        170        180 
FAAATWLRGI NFVQVPTSLL AMVDASIGGK TGVNHPKGKN LIGAFYQPRL VLIDPDTLKT 

       190        200        210        220        230        240 
LASREFRAGM AEVIKYGVIW DLELFEVLEG CDRTNQYRYM PPHILTEILT RSAQAKADVV 

       250        260        270        280        290        300 
TQDEKEAGLR AILNYGHTIG HAIESLTGYR LFNHGEAVAL GMVAAADIAV QLDWWSVEDA 

       310        320        330        340        350        360 
QRQHQLIQKT GLPTELPADF AIEAVADVLL TDKKVKDGKV RFILPTQLGK IDITDQVPGQ 

       370 
VIVSALKGMI GQ

« Hide

References

[1]"Niche adaptation and genome expansion in the chlorophyll d-producing cyanobacterium Acaryochloris marina."
Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J., Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y., Taylor H.L. expand/collapse author list , Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M., Blankenship R.E., Touchman J.W.
Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008) [PubMed: 18252824] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MBIC 11017.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000828 Genomic DNA. Translation: ABW30329.1.
RefSeqYP_001519648.1. NC_009925.1.

3D structure databases

ProteinModelPortalB0CBS9.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0CBS9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5684165.
GenomeReviewsGene locus AM1_5373 in contig CP000828_GR.
KEGGamr:AM1_5373.
PATRIC20624764. VBIAcaMar40141_4993.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG632303.
OMAVMALEMS.
PhylomeDBB0CBS9.

Enzyme and pathway databases

BioCycAMAR329726:AM1_5373-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_ACAM1
AccessionPrimary (citable) accession number: B0CBS9
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: February 26, 2008
Last modified: January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents