ID   B0CBA7_ACAM1            Unreviewed;       705 AA.
AC   B0CBA7;
DT   26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   26-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 87.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor {ECO:0000313|EMBL:ABW26746.1};
GN   OrderedLocusNames=AM1_1725 {ECO:0000313|EMBL:ABW26746.1};
OS   Acaryochloris marina (strain MBIC 11017).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Acaryochloridales;
OC   Acaryochloridaceae; Acaryochloris.
OX   NCBI_TaxID=329726 {ECO:0000313|EMBL:ABW26746.1, ECO:0000313|Proteomes:UP000000268};
RN   [1] {ECO:0000313|EMBL:ABW26746.1, ECO:0000313|Proteomes:UP000000268}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MBIC 11017 {ECO:0000313|Proteomes:UP000000268};
RX   PubMed=18252824; DOI=10.1073/pnas.0709772105;
RA   Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J.,
RA   Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D.,
RA   Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y.,
RA   Taylor H.L., Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M.,
RA   Blankenship R.E., Touchman J.W.;
RT   "Niche adaptation and genome expansion in the chlorophyll d-producing
RT   cyanobacterium Acaryochloris marina.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008).
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DR   EMBL; CP000828; ABW26746.1; -; Genomic_DNA.
DR   RefSeq; WP_012162263.1; NC_009925.1.
DR   AlphaFoldDB; B0CBA7; -.
DR   STRING; 329726.AM1_1725; -.
DR   KEGG; amr:AM1_1725; -.
DR   eggNOG; COG0745; Bacteria.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_50_3; -.
DR   OrthoDB; 543801at2; -.
DR   Proteomes; UP000000268; Chromosome.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   CDD; cd00156; REC; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 1.
DR   SMART; SM00091; PAS; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000268}.
FT   DOMAIN          10..127
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   DOMAIN          216..268
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          292..425
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          434..690
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
FT   MOD_RES         62
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   705 AA;  80560 MW;  E3322BA72DAB3D3D CRC64;
     MRHLDPLHIK LLLVEDDEDD YFFFEDLLDD FQSIQFDLDW ADTYDKGLEA VQRHQHDIYV
     FDFRLGSRTG LDLLEEVVAL GHRIPIILLT GQEDREIDLA AMTAGATDYL VKGMITSALL
     ERSIRYAINH TRTLVALQER EEQYNLVAQA SNDGLWDWNL QTHQVYYSPR WAAIIGQAEV
     TLQPSIQEWF DRIHPEDKER FRIDLRRHLR RETTAFECQY RMLHRDQSYR WVSSRGMAVF
     GPKNRVVRMA GSHTDLTNHV ALYDHLTGLP SRALFLDQLH RTLTRVNRQT NYLFAVLFLD
     CDRFKVINDS LGHAIGDQLL IEVAQRLTTA LRPGDVIARL GGDEFAILLE NIAGQDQAEQ
     VASRLNRELE KAFELQGHTV YISASIGIAL NSDHSPQAEN LLRDADNAMY RAKALGKSRY
     VVFEAAMRDR VQALLRVETD LRAAIANQEF QLYYQPIISL KTHEIVSLEA LIRWQHPQRG
     LISPQEFIPV AEETGLILAI GQWVLEESCQ QLWQWHQTLT EIPPLSISVN LSRKQFSQAS
     LGKQIQSILS ETGVSARHLK LEITETMIME NEVMVSELIS QLRALGLQLQ IDDFGTGYSS
     LSFLHNFPLD TLKIDRSFIE GLVTDTEKSE IVRTMITLAH NLGMTAIAEG VETQAQLQWL
     QQHHCDCVQG YLLSKPLSAA QMQKALMQSH RVFVQPLETS TVVSA
//