B0CB11 (ACKA_ACAM1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetate kinase
EC=2.7.2.1

Alternative name(s):
Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	AM1_0445

Organism

Acaryochloris marina (strain MBIC 11017) [Complete proteome] [HAMAP]

Taxonomic identifier

329726 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Acaryochloris

Protein attributes

Sequence length	398 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 398	398	Acetate kinase HAMAP MF_00020		PRO_1000089955

Sequences

	Sequence		Length	Mass (Da)
	B0CB11 [UniParc]. Last modified February 26, 2008. Version 1. Checksum: AF3C9FEBE6DCDB4B	FASTA	398	43,410
	10 20 30 40 50 60 MKILVLNAGS SSHKCCLYAI EGPLPDHPAP PLWEAQLDWH DPNHASLKVK TKRENLEEDL 70 80 90 100 110 120 SDVSRADALS HLLTTLWHGP TQVIQMAQEI NVVGHRVVHG GQDYQSSVVV TSEVKTAIAD 130 140 150 160 170 180 LIPLAPNHNP ANLEGIKLIE QLLGNVRQVA VFDTAFHSHL PEVAAIYPGP YDWQQQGIRR 190 200 210 220 230 240 YGFHGISHQY CTQRTAEILG RGVDRLIICH LGNGASLTAV KQGQSIDTSM GFTPLEGLMM 250 260 270 280 290 300 GTRSGSIDPG ILIHLMRQGY DADQLDHMLN KASGLKGISG VSHDLREIEQ AIAQDNAQAK 310 320 330 340 350 360 LARDLYLHRL KACLGSMLMS LGGVDVLVFT GGIGEHSASV RAETCEALAF LGLKLDPILN 370 380 390 RKSPVDQDIA AVDSKVRVLV IKTQEDWAIA QSCYEQCC

References

[1]

"Niche adaptation and genome expansion in the chlorophyll d-producing cyanobacterium Acaryochloris marina." Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J., Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y., Taylor H.L. , Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M., Blankenship R.E., Touchman J.W. Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008) [PubMed: 18252824] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MBIC 11017.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000828 Genomic DNA. Translation: ABW25501.1.
RefSeq	YP_001514815.1. NC_009925.1.
3D structure databases
ProteinModelPortal	B0CB11.
ModBase	Search...
Protein-protein interaction databases
STRING	B0CB11.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5679276.
GenomeReviews	Gene locus AM1_0445 in contig CP000828_GR.
KEGG	amr:AM1_0445.
PATRIC	20615436. VBIAcaMar40141_0370.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG285863.
OMA	IGEHQPE.
PhylomeDB	B0CB11.
ProtClustDB	PRK00180.
Enzyme and pathway databases
BioCyc	AMAR329726:AM1_0445-MONOMER.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR004372. Ac/Proprionate_kinase. IPR000890. Aliphatic_acid_kin_short-chain. IPR023865. Aliphatic_acid_kinase_CS. [Graphical view]
KO	K00925.
PANTHER	PTHR21060. Acetate_kin. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. AckA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_ACAM1

Accession

Primary (citable) accession number: B0CB11

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	February 26, 2008
Last modified:	January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program